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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by Diego55 on November 2, 2009, at 19:21:31
Hello, I want to ask a few questions about phenylethylamine (PEA) + Selegiline + Carvedilol/NRI combo :
Could you please write me the exact procedure, how to use selegiline with PEA ?
Which PEA dose would be perfect to get a prosocial + AD effect ? Is there inderal or extra Carvedilol necessary? Is there a really big difference on dopamine activity between 5mg Selegiline daily or 10 mg daily?
Do you think it can be a long term solution or just be used recreationally because of short duration of action ?How long is the duration of action or how often do I have to redose in your opinion(including doses please) ? Could you also write me please, how to extend the duration of combo effect ?
What are the side effects of PEA + Selegiline? What could I take to taper off the comedown?
Sorry for all the questions, but I want to know all about this combo and you are quite knowledgeable about it.I want to try this for my social phobia.
Many Thanks
Posted by Rosy Crucifiction on November 3, 2009, at 11:32:41
In reply to Phenylethylamine(PEA) + selegiline - questions, posted by Diego55 on November 2, 2009, at 19:21:31
I've tried the dosages on the trial below for depression and had the positive effects fade in a few days. However, that was with the liquid Ceprenyl version. In spite of opinion to the contrary, I think prescribed tablets are the best bet. I have found them more like Emsam in later trials. 10- to 20 mg. a day for depression. Keep a BP cuff around and check your BP using PEA. There is some danger of a hypertensive spike from the cascade effect of PEA induced increase of dopamine on norepinephrine. An Ace inhibitor or Beta blocker should take care of any issues.
"Sustained antidepressant effect of PEA replacement
by
Sabelli H, Fink P, Fawcett J, Tom C
Rush University and the
Center for Creative Development,
Chicago, Illinois, USA.
J Neuropsychiatry Clin Neurosci 1996 Spring; 8(2):168-71ABSTRACT
Phenylethylamine (PEA), an endogenous neuroamine, increases attention and activity in animals and has been shown to relieve depression in 60% of depressed patients. It has been proposed that PEA deficit may be the cause of a common form of depressive illness. Fourteen patients with major depressive episodes that responded to PEA treatment (10-60 mg orally per day, with 10 mg/day selegiline to prevent rapid PEA destruction) were reexamined 20 to 50 weeks later. The antidepressant response had been maintained in 12 patients. Effective dosage did not change with time. There were no apparent side effects. PEA produces sustained relief of depression in a significant number of patients, including some unresponsive to the standard treatments. PEA improves mood as rapidly as amphetamine but does not produce tolerance."
Posted by Diego55 on November 8, 2009, at 14:11:32
In reply to Re: Phenylethylamine(PEA) + selegiline - questions, posted by Rosy Crucifiction on November 3, 2009, at 11:32:41
thanks for answer, do you knows how to extend the duration of combo effect ?
This is the end of the thread.
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