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Re: Phenylethylamine(PEA) + selegiline - questions

Posted by Rosy Crucifiction on November 3, 2009, at 11:32:41

In reply to Phenylethylamine(PEA) + selegiline - questions, posted by Diego55 on November 2, 2009, at 19:21:31

I've tried the dosages on the trial below for depression and had the positive effects fade in a few days. However, that was with the liquid Ceprenyl version. In spite of opinion to the contrary, I think prescribed tablets are the best bet. I have found them more like Emsam in later trials. 10- to 20 mg. a day for depression. Keep a BP cuff around and check your BP using PEA. There is some danger of a hypertensive spike from the cascade effect of PEA induced increase of dopamine on norepinephrine. An Ace inhibitor or Beta blocker should take care of any issues.

"Sustained antidepressant effect of PEA replacement
by
Sabelli H, Fink P, Fawcett J, Tom C
Rush University and the
Center for Creative Development,
Chicago, Illinois, USA.
J Neuropsychiatry Clin Neurosci 1996 Spring; 8(2):168-71

ABSTRACT

Phenylethylamine (PEA), an endogenous neuroamine, increases attention and activity in animals and has been shown to relieve depression in 60% of depressed patients. It has been proposed that PEA deficit may be the cause of a common form of depressive illness. Fourteen patients with major depressive episodes that responded to PEA treatment (10-60 mg orally per day, with 10 mg/day selegiline to prevent rapid PEA destruction) were reexamined 20 to 50 weeks later. The antidepressant response had been maintained in 12 patients. Effective dosage did not change with time. There were no apparent side effects. PEA produces sustained relief of depression in a significant number of patients, including some unresponsive to the standard treatments. PEA improves mood as rapidly as amphetamine but does not produce tolerance."


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poster:Rosy Crucifiction thread:924181
URL: http://www.dr-bob.org/babble/20091029/msgs/924286.html