Psycho-Babble Medication Thread 915556

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Does Quercetin interact with Citalopram?

Posted by Jackster on September 3, 2009, at 5:36:47

I'd like to take a supplement that contains Quercetin for interstitial cystitis, but I can't seem to find out whether it would interact with the citalopram I'm on. I read somewhere that Quercetin is metabolised through cytochrome CP450, but didn't get any more details than that. Does anyone out there know, or know where I can find more about possible interactions with this supplement?

Thanks
Jax

 

Re: Does Quercetin interact with Citalopram? » Jackster

Posted by tensor on September 3, 2009, at 8:47:20

In reply to Does Quercetin interact with Citalopram?, posted by Jackster on September 3, 2009, at 5:36:47

> I'd like to take a supplement that contains Quercetin for interstitial cystitis, but I can't seem to find out whether it would interact with the citalopram I'm on. I read somewhere that Quercetin is metabolised through cytochrome CP450, but didn't get any more details than that. Does anyone out there know, or know where I can find more about possible interactions with this supplement?
>
> Thanks
> Jax

Sure, I use these:
http://www.drugs.com/drug_interactions.html

http://www.drugdigest.org/wps/portal/!ut/p/c1/fZBdjoIwAITP4gFIy09VHgsLWBAE-ZHyYkBBSwWErIKcfvUA7szbJDOTfCADb7f5k13yX9a1-Q2kIFseZWhBaOkkhiaRIVlv3PUW79-pCA6fxvIIvwhD4G26pgQUZKuvO2sJJG03NJ-_JytHEIHUo9L005HRNJLj_aAsG6t0ifPUlR43yo1YnJ_RGNAuSgT72gtynRoqEvZl72g6qhIeOF3aV4j5W17R4Bqaoe6HBd2U8eXFd_xRF6F6iWZf5FA6O85Jyl1JtJTK0_CLpTGKBii1J2ZbpU_vA-qRbGoWtKfzzEgwuLsCwW0Qs0rCM3-EK1vItVrl1cRrMeNeD1ViTKW4m1szq3B3Mwq8WLwp0H8p3Hk7jinCf8WKpa4!/dl2/d1/L2dNQSEvUUd3QlFnISEvWUJwNDF3ISEvNl8zMEcwMEdDSVUwRkkzMEk4SE04TEFSMzBHMS83XzMwRzAwR0NJVTBGSTMwSThITThMQVIzMDgy/

http://www.medscape.com/druginfo/druginterchecker

Regards,
Mattias

 

Re: Does Quercetin interact with Citalopram?

Posted by Jackster on September 5, 2009, at 17:48:52

In reply to Re: Does Quercetin interact with Citalopram? » Jackster, posted by tensor on September 3, 2009, at 8:47:20

Thanks Mattias. Unfortunately Quercetin doesn't seem to be on the lists for any of those.

Jax

 

Re: Does Quercetin interact with Citalopram? » Jackster

Posted by Larry Hoover on September 5, 2009, at 22:15:43

In reply to Does Quercetin interact with Citalopram?, posted by Jackster on September 3, 2009, at 5:36:47

> I'd like to take a supplement that contains Quercetin for interstitial cystitis, but I can't seem to find out whether it would interact with the citalopram I'm on. I read somewhere that Quercetin is metabolised through cytochrome CP450, but didn't get any more details than that. Does anyone out there know, or know where I can find more about possible interactions with this supplement?
>
> Thanks
> Jax

Although both substances have substantial involvement with the CYP450 liver enzymes, they appear to have no overlap in those effects. Quercetin involves 1A1/1A2, 2A6, and 2C8.
Citalopram involves 2C19, and 3A4.

I anticipate no significant interaction between quercetin and citalopram.

Lar

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