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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Malcolm6491 on August 11, 2009, at 0:52:33
Ok, I started taking Seroquel at a much higher dose than I have been (100 mg); up to that point I had only been on 50 mgs.
For the first few days, it worked wonderfully, no probs sleeping and much reduced daytime drowsiness at work than when I had been on Xanax (which didn't work all that well for the anxiety either -- I've never had much luck with any of the benzos).
But now, it's close to 1:42 am in the morning and I can't sleep (I'm up typing the message)!! So why isn't the Seroquel working anymore? And after just one week!?! Just a few days ago, I felt the anxiety diminished greatly, and I slept like a baby for almost the entire night.
What gives? I have an appointment with my p-doc on the 25th Aug, so have to wait until then to talk with him.
I'm just wondering if diarrhea could be the cause of this reaction. Could the diarrhea I've had for the last couple of days have anything to do with it? (I'm thinking b/c it could have caused the med to be eliminated from my system).
I realize there are no easy answers, esp when trying to dispense advice to a complete stranger.
But seriously, the diarrhea is the only reason I can think of. Any ideas?
Posted by viper1431 on August 11, 2009, at 1:31:54
In reply to Question about seroquel, posted by Malcolm6491 on August 11, 2009, at 0:52:33
Alot of people get over the sleepiness effect of seroquel after being on it for a little while so it no longer puts them to sleep. You may have just become accustomed to it already.
Posted by chumbawumba on August 11, 2009, at 1:45:38
In reply to Re: Question about seroquel » Malcolm6491, posted by viper1431 on August 11, 2009, at 1:31:54
That happened to me, the initial soporific effect wore off. I had to go up to 100-200 mg a day for sleep. I tended to oversleep though.
Posted by Sunbath on August 11, 2009, at 3:38:25
In reply to Question about seroquel, posted by Malcolm6491 on August 11, 2009, at 0:52:33
Hi Malcolm!
Today was my 7th night with Seroquel 25mg and it was like you say. I too have built up tolerance to the sedative effect, but still my mind is a bit foggy during the day. Ok 25mg isn't much, but if you say this happens to you at a dose of 100mg, this isn't very encouraging..But this remembers me of trazodone: First I could sleep VERY well on 50mg, then soon I had built up some tolerance and I needed to go up to 100, then 150.. at 150 now there's some sleep promoting effect for me that doesn't fade over time it seems.. since taking trazodone (>2.5yrs) I've never had trouble falling asleep anymore (took ~1-2 hours before). Now my problem's early awakenings and anxiety...
Have you already tried trazodone or low doses of potent antihistamine drugs like amitriptyline, doxepine?
Good luck to you!!
Posted by Phillipa on August 11, 2009, at 12:24:11
In reply to Re: Question about seroquel, posted by Sunbath on August 11, 2009, at 3:38:25
Interesting as for the 40 years of low dose benzos they still put me to sleep and worn off by morning. So this means to me that the atypicals also poop out. Not trying to be negative just an observation. I was in medicine so always looking for trends. Phillipa
This is the end of the thread.
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