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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 12 to 36 of 36. Go back in thread:
Posted by aaaaalex on May 8, 2008, at 2:02:41
In reply to Re: Is amineptine (survector) totally extinct?, posted by Ezekiel on May 5, 2008, at 15:55:50
Most of the amineptine available is in "research chemical" form, which is not something I personally would care to ingest. It's not impossible that someone horded large amounts of Survector, but since the availability is so low and only from dubious sources, it doesn't seem like a good idea. Even if it worked wonders, there's no guarantee that you'd be able to obtain it in the future.
Also, while Pearce's info can be very useful, his views are fairly extreme, and his information often disagrees with my personal experience - for example, SSRIs work fairly well for me, and I disagree with his blanket categorization of some drugs as "pro-sexual". Take it with a grain of salt.
Posted by undopaminergic on May 8, 2008, at 6:52:20
In reply to Re: Is amineptine (survector) totally extinct?, posted by Ezekiel on May 8, 2008, at 0:01:45
> Undopaminergic - true it's not very cost-effective, but perhaps if one looks at it from a different vantage point, then from there maybe it would not be perceived as such a great financial sacrifice.
>
> Well, what if someone chose to view their AD regimen in that light, i.e., as something indispensable to the quality of their life? TO ME, paying $285 to liberate myself from intractable & relentless depression is very much worth it, but this assumes the medication(s) proved effective.
>I agree that an effective antidepressant - or anything else that drastically enhances one's health or capabilites - is well worth paying for. My point was that there are almost certainly more cost-effective alternatives to amineptine at the price quoted.
Posted by Phaedrus D on May 8, 2008, at 9:50:58
In reply to Re: Is amineptine (survector) totally extinct?, posted by Ezekiel on May 5, 2008, at 15:55:50
I just put in an order for a full months supply from the only source available. He plainly states that it is a research chemical and is custom synthesized by a chemical supply company to greater than 97% purity. Well, since no pharma company produces Survector anymore, this is what were left with. Im willing to roll the dice and try some because, simply put, I cant live like this anymore. I can get decent symptomatic improvement of my Sluggish Cognitive Tempo with poly-drug therapy (parnate, adderall, provigil, etc) but I have horrible insomnia and these meds cut my sleep time down to a few hors a night. Im hoping that the survector will confer an efficacious treatment modality for my SCT.
Posted by okydoky on May 8, 2008, at 13:05:55
In reply to Re: Is amineptine (survector) totally extinct?, posted by Ezekiel on May 8, 2008, at 0:01:45
> Undopaminergic - true it's not very cost-effective, but perhaps if one looks at it from a different vantage point, then from there maybe it would not be perceived as such a great financial sacrifice.
>
> What I mean is this, what if one opted to cut back on watching movies, buying CD's, habitually eating out (expensive garbage food), eliminating expensive caffeine consumption (triple starbuck's mochas) etc., then $285 per month may become a more reasonable consideration - what is a life free from the despair of depression worth? Can that be quantified? Most of us choose a car payment that is somewhere in the vicinity of $300 a month, we choose this because we perceive a car to be an indispensable part of how we want to live our lives.
>
> Well, what if someone chose to view their AD regimen in that light, i.e., as something indispensable to the quality of their life? TO ME, paying $285 to liberate myself from intractable & relentless depression is very much worth it, but this assumes the medication(s) proved effective.
>
> I think it really reduces to what we as individuals value in this brief span of time we call life, e.g., if one highly values impressing other people, then spending $285 on medication will be seen as excessive, and perhaps even WASTEFUL, since one could have spent that money on expensive clothes or a nicer car to fulfill this personal need - our value judgments largely determine our thoughts & behavior I believe . . . Zeke
I find it astonishing that people I know will spend large amounts of money on items like clothing or expensive cars or simply being part of the disposable society. For example, throwing away perfectly good furniture to replace it with a newer version. One person I know needed a new washer and disposed of her dryer because she insisted they had to match. The same person fights with her insurance company for trivial medications sometimes other times expensive ones but suffers without these that could possibly have a tremendous effect on her quality of life. People don't seem to understand that things do not improve the quality of ones life most especially if depressed when you cannot enjoy or appreciate them. Quality or quantity. Most in this country no matter what the content will opt for quantity. They are used to things being disposable so buy cheap and often. Unfortunately life is not a disposable commodity!
Posted by okydoky on May 8, 2008, at 13:07:41
In reply to Re: Is amineptine (survector) totally extinct?, posted by Phaedrus D on May 8, 2008, at 9:50:58
> I just put in an order for a full months supply from the only source available. He plainly states that it is a research chemical and is custom synthesized by a chemical supply company to greater than 97% purity. Well, since no pharma company produces Survector anymore, this is what were left with. Im willing to roll the dice and try some because, simply put, I cant live like this anymore. I can get decent symptomatic improvement of my Sluggish Cognitive Tempo with poly-drug therapy (parnate, adderall, provigil, etc) but I have horrible insomnia and these meds cut my sleep time down to a few hors a night. Im hoping that the survector will confer an efficacious treatment modality for my SCT.
I am also currently trying amineptine again. Could you keep me or us informed as to how you do on it?Thanks,
okydoky
Posted by undopaminergic on May 8, 2008, at 13:17:44
In reply to Re: Is amineptine (survector) totally extinct?, posted by okydoky on May 8, 2008, at 13:07:41
>
> I am also currently trying amineptine again. Could you keep me or us informed as to how you do on it?
>It would be interesting if you could elaborate on your experience with amineptine - especially (but not limited to) how it compares to closely related drugs such as tianeptine (structurally similar), methylphenidate and amphetamine (pharmacodynamically related).
Posted by eric wagner on May 9, 2008, at 11:09:55
In reply to Re: Is amineptine (survector) totally extinct?, posted by Phaedrus D on May 8, 2008, at 9:50:58
Phaedrus D,
please post how much you paid, your payment method, when you recieve it & how it feelsi am seriously considering the same option
thanks
eric m. wagner
Posted by Quintal on May 9, 2008, at 16:36:12
In reply to Re: Is amineptine (survector) totally extinct?, posted by Phaedrus D on May 8, 2008, at 9:50:58
> I just put in an order for a full months supply from the only source available. He plainly states that it is a research chemical and is custom synthesized by a chemical supply company to greater than 97% purity. Well, since no pharma company produces Survector anymore, this is what were left with.
I get pure GHB powder direct from a pharmaceutical company in Ireland. Beats the crap out of Xyrem price-wise. I can't believe how much that drug costs on precription.
The amineptine is probably still good quality stuff even though it's produced as a research chemical. Afterall it wouldn't be used for research unless it was reliable.
Q
Posted by okydoky on May 9, 2008, at 16:52:09
In reply to Re: Is amineptine (survector) totally extinct?, posted by Quintal on May 9, 2008, at 16:36:12
"The amineptine is probably still good quality stuff even though it's produced as a research chemical. Afterall it wouldn't be used for research unless it was reliable."
Seriously!!!
Not denying the quality in any way but the stuff is off the market. There is no research!
Posted by okydoky on May 9, 2008, at 17:32:59
In reply to Re: Is amineptine (survector) totally extinct?, posted by Phaedrus D on May 8, 2008, at 9:50:58
To Phaedrus D
I believe I reived a post form you and somehow lost it? I did not reply as I had to think about what you had inquired about.
Sorry
Posted by Quintal on May 9, 2008, at 17:39:19
In reply to Re: Is amineptine (survector) totally extinct?, posted by okydoky on May 9, 2008, at 16:52:09
>Not denying the quality in any way but the stuff is off the market. There is no research!
Loads of psychoactive drugs are used in research labs that never will/never did see the light of day on the commercial market.
Q
Posted by undopaminergic on May 9, 2008, at 19:07:52
In reply to Re: Is amineptine (survector) totally extinct?, posted by Quintal on May 9, 2008, at 16:36:12
> > I just put in an order for a full months supply from the only source available. He plainly states that it is a research chemical and is custom synthesized by a chemical supply company to greater than 97% purity. Well, since no pharma company produces Survector anymore, this is what were left with.
>
> I get pure GHB powder direct from a pharmaceutical company in Ireland. Beats the crap out of Xyrem price-wise. I can't believe how much that drug costs on precription.
>
> The amineptine is probably still good quality stuff even though it's produced as a research chemical. Afterall it wouldn't be used for research unless it was reliable.
>Indeed, ordering pure chemicals can be even more reliable than finished pills or capsules. Many chemical products are certified 99%+ pure, whereas tablets and capsules are virtually always diluted with excipients such as talc and lactose.
Posted by okydoky on May 9, 2008, at 19:10:58
In reply to Re: Is amineptine (survector) totally extinct? » okydoky, posted by Quintal on May 9, 2008, at 17:39:19
Posted by okydoky on May 10, 2008, at 13:09:17
In reply to Re: Is amineptine (survector) totally extinct?, posted by undopaminergic on May 9, 2008, at 19:07:52
I am reminded that I have heavily relied upon this site to gain insight, knowledge and perhaps hope from both other peoples experiences and their willingness both to share in them and to interact with others, like myself, who perhaps have more questions than answers. People have been kind and patient here in interacting with me so that I may be able to make more informed decisions with regard to medications for my depression.
I am not so eloquent a writer nor do I have the depth of knowledge that many on this site seem to have. With all this in mind I thought it requisite to post some about my experience with amineptine.
I have had several trials on it. Starting I believe in 2005. Each time seems to be different. If you want to look up what I have previously posted the name is iris2. Recently in February I did a week trial and within two days felt more energized. I stopped taking my usual Ritalin 20mg in the morning. I felt significantly less depressed in that weeks time and noticed less sensation of pain from other ailments.
I ordered a months worth based on this and prior experience with the hope that I would get the same response and perhaps more improvement as I would have a longer trial. I was unable to take it the second time. There were so many variables but I thought perhaps the second time I received something different.
I can now say 5 days into this trial with certainty that the problems I had were not due to the medication itself but to my preexisting illness.
This time I felt some improvement the first two days and on the third day felt more lethargic and had to start taking the Ritalin again. I can only report that this time I see no improvement. I have increased the dose to 200mg a day starting yesterday. Strangely I am feeling more lethargic and tired as I did the second time when I had to stop because of other problems but I thought it was due to pain then.
If anyone has specific questions post them here or babble me. Else I will be needlesly wordy! I plan on continuing this trial for another week or more. I do not want to stop short and always have a nagging question in the back of my head that I never gave it a chance.
I would appreciate it very much if others would post their experiences with amineptine. It will help me and others assess their response to the medication and help others decide if this is a course of treatment for them.
Thanks
Oky
Posted by undopaminergic on May 11, 2008, at 12:18:28
In reply to amineptine (survector) experience, posted by okydoky on May 10, 2008, at 13:09:17
Thanks for sharing your amineptnie experience.
One possible explanation for the diminished quality of later experiences in comparison with the first may be that the supplier has resorted to deluting ("cutting") the amineptine with cheaper filler ingredients. This might be noticeable as subtle changes in taste, texture or solubility. However, this is just speculation.
At the usual doses, amineptine is a dopamine reuptake inhibitor, much like methylphenidate, which is a dopamine and noradrenaline reuptake inhbitor. At high doses, ampineptine may also elicit enhanced release of dopamine, much like amphetamines (and phenylethylamine, PEA).
I suspect that amineptine may also have additional properties, some of which may possibly be shared by tianeptine (Stablon, Coaxil), a stucturally similar antidepressant from the same company and that is not a dopamine reuptake inhibitor.
It may be interesting to compare the effects of amineptine with those of tianeptine, and perhaps more pertinently, the combination of tianeptine with methylphenidate, modafinil or both.
Posted by okydoky on May 11, 2008, at 13:29:26
In reply to Re: Is amineptine (survector) totally extinct?, posted by Phaedrus D on May 8, 2008, at 9:50:58
I started taking the 20mg of Ritalin I usually take. With that addition I am very stimulated. I was having more difficulty motivating myself to get out of bed again and needed to add it back. As of yet I see no improvement in my depressive symptoms. Perhaps that is still to come.
I connot take tianeptine. Modafranil agitated me too much although my old pdoc suggested that it would have probably stopped having that effect had I stuck with it longer.
Another poster suggested augmenting the Amineptine with Abilify, Lamictal or nortriptyline.I have Lamictal, Cymbalta, Ritalin and Elavil at hand now.
By the way I am getting acne already. I had my liver enzymes checked before starting this because of what I read.
Let us know about your experience Phaedrus D.I had great symptom improvement on Parnate also for several years. I never could sleep on the stuff no matter what I tried. Had Parnte poop out or whatever the correct term is. I might try it again if this does not pan out.
oky
Posted by elanor roosevelt on May 11, 2008, at 14:21:43
In reply to Re: Is amineptine (survector) totally extinct?, posted by Ezekiel on May 5, 2008, at 15:55:50
> Thnanks for the replys everyone - I located a survector supplier in the US who is loosely associated with David Pearce at this site: http://www.hedweb.com/hedethic/tabconhi.htm It is expensive, $285 for a 1 month supply.
>
> where at the site did you find it?
Posted by undopaminergic on May 11, 2008, at 15:49:52
In reply to Re: Is amineptine (survector) totally extinct?, posted by okydoky on May 11, 2008, at 13:29:26
>
> I connot take tianeptine.
>Why not?
>
> Another poster suggested augmenting the Amineptine with Abilify, Lamictal or nortriptyline.
>Abilify may augment, or it may antagonise. Amisulpride or sulpiride, at low doses, would presumably augment or do nothing, so I would try those first (they may augment Ritalin too). Selegiline and rasagiline may also be of interest as additions. Last, but not least, memantine has in several cases been effective in preventing tolerance to stimulants, but in my experience it's more useful than that, and it's certainly worthy of consideration for almost anyone who responds well to stimulants - or amineptine.
>
> By the way I am getting acne already. I had my liver enzymes checked before starting this because of what I read.
>I can't recall hearing of an issue with liver enzymes resulting from amineptine, but I imagine it can happen in rare cases with almost anything.
>
> I had great symptom improvement on Parnate also for several years. I never could sleep on the stuff no matter what I tried.
>Did you try anything with serotonin 5-HT2A-receptor antagonism? Cyproheptadine (Periactin) has that property in addition to being a sedating antihistamine. If required, combining such an agent with a benzodiazepine or Z-drug would be possible.
Posted by garylee on May 11, 2008, at 22:07:33
In reply to amineptine (survector) experience, posted by okydoky on May 10, 2008, at 13:09:17
> I am reminded that I have heavily relied upon this site to gain insight, knowledge and perhaps hope from both other peoples experiences and their willingness both to share in them and to interact with others, like myself, who perhaps have more questions than answers. People have been kind and patient here in interacting with me so that I may be able to make more informed decisions with regard to medications for my depression.
>
> I am not so eloquent a writer nor do I have the depth of knowledge that many on this site seem to have. With all this in mind I thought it requisite to post some about my experience with amineptine.
>
> I have had several trials on it. Starting I believe in 2005. Each time seems to be different. If you want to look up what I have previously posted the name is iris2. Recently in February I did a week trial and within two days felt more energized. I stopped taking my usual Ritalin 20mg in the morning. I felt significantly less depressed in that weeks time and noticed less sensation of pain from other ailments.
>
> I ordered a months worth based on this and prior experience with the hope that I would get the same response and perhaps more improvement as I would have a longer trial. I was unable to take it the second time. There were so many variables but I thought perhaps the second time I received something different.
>
> I can now say 5 days into this trial with certainty that the problems I had were not due to the medication itself but to my preexisting illness.
>
> This time I felt some improvement the first two days and on the third day felt more lethargic and had to start taking the Ritalin again. I can only report that this time I see no improvement. I have increased the dose to 200mg a day starting yesterday. Strangely I am feeling more lethargic and tired as I did the second time when I had to stop because of other problems but I thought it was due to pain then.
>
> If anyone has specific questions post them here or babble me. Else I will be needlesly wordy! I plan on continuing this trial for another week or more. I do not want to stop short and always have a nagging question in the back of my head that I never gave it a chance.
>
> I would appreciate it very much if others would post their experiences with amineptine. It will help me and others assess their response to the medication and help others decide if this is a course of treatment for them.
>
> Thanks
>
> Oky
>
Just a thought... Could the lethargy you experienced a few days in to the trial be a withrawal symptom from the Ritalin? Perhaps you should stay on your current reigeim and just add the Amineptine to the mix? I take Lamictal 200mg, Sulpiride 100mg and Seroquel 50mg and Clonazepam 2mg for sleep for my Bipolar (NOS). I too am ordering Amineptine to try. I would say you can't put a price on happiness after feeeling depresed and suicidal for the last 10 or so years...Some of you may, some of you may not agree with my other next med choice. Hydrocodone. I have found a source for this also and will be experimenting after the Amineptine if it isn't 'the one'.
And seeing as we're are on the subject of Dopaminergics, I would recommend to anyone to try Pramipexole. I responed extremely well a few years back, I'd say almost 'cured' at the maximim dose but stopped it to try another DA, Trivistal. When I went back to the Pramipexole it didn't seem to work as well... Not sure why.
Just my two pence... :O)
Posted by cumulative on May 12, 2008, at 1:43:27
In reply to Re: Is amineptine (survector) totally extinct?, posted by undopaminergic on May 11, 2008, at 15:49:52
Mild mood enhancement over time, and, I think, more ease with socializing. Again, very mild -- I think I found Tianeptine stronger, even at the 12.5mg dose. No significant increase in ability to focus, unfortunately.
A low dose (around 30mg) helped my sleep considerably and I was waking up refreshed for the first time in a long while.
Decent stuff for me -- I would probably be happy to keep it around if it wasn't now so ridiculously expensive.
I was taking 150mg daily (costing over $300 monthly). I think a higher dose might have been more effective.
Posted by okydoky on May 12, 2008, at 9:31:12
In reply to Re: Is amineptine (survector) totally extinct?, posted by undopaminergic on May 11, 2008, at 15:49:52
> > I connot take tianeptine.
> Why not?
> Abilify may augment, or it may antagonise. Amisulpride or sulpiride, at low doses, would presumably augment or do nothing, so I would try those first (they may augment Ritalin too). Selegiline and rasagiline may also be of interest as additions. Last, but not least, memantine has in several cases been effective in preventing tolerance to stimulants, but in my experience it's more useful than that, and it's certainly worthy of consideration for almost anyone who responds well to stimulants - or amineptine.
>
> Did you try anything with serotonin 5-HT2A-receptor antagonism? Cyproheptadine (Periactin) has that property in addition to being a sedating antihistamine. If required, combining such an agent with a benzodiazepine or Z-drug would be possible.
> > I connot take tianeptine.
> Why not?
> Abilify may augment, or it may antagonise. Amisulpride or sulpiride, at low doses, would presumably augment or do nothing, so I would try those first (they may augment Ritalin too). Selegiline and rasagiline may also be of interest as additions. Last, but not least, memantine has in several cases been effective in preventing tolerance to stimulants, but in my experience it's more useful than that, and it's certainly worthy of consideration for almost anyone who responds well to stimulants - or amineptine.
>
> Did you try anything with serotonin 5-HT2A-receptor antagonism? Cyproheptadine (Periactin) has that property in addition to being a sedating antihistamine. If required, combining such an agent with a benzodiazepine or Z-drug would be possible.Firstly I cannot take a lot of drugs because of a preexisting bladder disease called Interstitial Cystitis.
I do not quite understand "antagonise" could you explain simply?
Amisulpride caused prolactin problems in the past. I had to discontinue.Not sure about Selegiline or rasagiline but someone else said they had taken it with amineptine. Will consider. With consideration to my cognitive impairment this looks attractive. Which one? Need to check out memantine.
Barring the drugs you mentioned 5-HT2A-receptor antagonism I am not familiar enough to say either way if I have tried one. Certainly not the two you mentioned. IF I end up tryng Parnate again which is likely I want to revisit this.Thanks ro the advise,
oky
Posted by okydoky on May 13, 2008, at 13:29:15
In reply to amineptine (survector) experience, posted by okydoky on May 10, 2008, at 13:09:17
This is the 8th day on amineptine. (I had miss counted.) Started adding Lamictal yesterday at 25mg. Definitely agitated but not much else.
I think I might stop taking it as I cannot afford more right now and am not sure what to augment it with. I would have about two weeks medication left to try again. I have gotten suggestions but decisions are difficult for me in depression. I needed to go online and find Abilify and Selegiline which I now have but it would still take some time before I have them. I have Lamical on hand.(Elavil also)
Suggestions have been nortriptyline, Lamictal, Abilify and Selegiline. Not sure on the doses.
I just do not get why amineptine works one time and not another. In February for the week I tried it I felt measurably better in mood, motivation, energy and pain sensation. Yet now I feel none of this. What could have changed in two or three months?
I know I have been posting here constantly. I am feeling desperate and trying to get help and based on it make decisions. Decisions are impossible for me in this state. Perhaps at this
juncture it would be best for me to stop and retry Parnate again. Since it pooped out for me I have tried it numerous times with no result but not in several years.Please know I appreciate both the help and the tolerance.
oky
Posted by undopaminergic on May 15, 2008, at 15:54:38
In reply to Re: Is amineptine (survector) totally extinct?, posted by okydoky on May 12, 2008, at 9:31:12
>
>
> > > I connot take tianeptine.
>
> > Why not?
>
>
> > Abilify may augment, or it may antagonise. Amisulpride or sulpiride, at low doses, would presumably augment or do nothing, so I would try those first (they may augment Ritalin too). Selegiline and rasagiline may also be of interest as additions. Last, but not least, memantine has in several cases been effective in preventing tolerance to stimulants, but in my experience it's more useful than that, and it's certainly worthy of consideration for almost anyone who responds well to stimulants - or amineptine.
> >
>
>
> > Did you try anything with serotonin 5-HT2A-receptor antagonism? Cyproheptadine (Periactin) has that property in addition to being a sedating antihistamine. If required, combining such an agent with a benzodiazepine or Z-drug would be possible.
>
>
>
> Firstly I cannot take a lot of drugs because of a preexisting bladder disease called Interstitial Cystitis.
>
> I do not quite understand "antagonise" could you explain simply?
>I meant that aripiprazole (Abilify) may reduce the effectiveness of the amineptine - this is a definite risk, but some people find Abilify energising, and it's also possible that it would work well in combination with amineptine. Only by testing it in the individual case can the outcome be determined.
> Amisulpride caused prolactin problems in the past. I had to discontinue.
>Prolactin problems? Like sexual dysfunction and galactorrhoea?
> Not sure about Selegiline or rasagiline but someone else said they had taken it with amineptine. Will consider. With consideration to my cognitive impairment this looks attractive. Which one?
>Selegiline is cheaper; it also differs from rasagiline in that its extensively metabolised into several pharmacologally active substances, including amphetamines; also in contrast to rasagiline, selegiline has affinity to the alpha2B-adrenergic receptor. You'll have to decide for yourself whether any of that is of significance.
Posted by okydoky on May 15, 2008, at 20:10:52
In reply to Re: Is amineptine (survector) totally extinct?, posted by undopaminergic on May 15, 2008, at 15:54:38
> Amisulpride caused prolactin problems in the past. I had to discontinue.
> >
>
> Prolactin problems? Like sexual dysfunction and galactorrhoea?
>
>
> Selegiline is cheaper; it also differs from rasagiline in that its extensively metabolised into several pharmacologally active substances, including amphetamines; also in contrast to rasagiline, selegiline has affinity to the alpha2B-adrenergic receptor. You'll have to decide for yourself whether any of that is of significanceThe Prolactin elevation was called Hyperprolactinaemia. My doc said it was if I was pregnant and lactating. I did not get my period for months ,my entire body shape changed and I had some leakage from my breasts.
"You'll have to decide for yourself whether any of that is of significance"
Me make a decision about something I barely understand! and if I eventualy with study could it would be too late for this trial!
THanks
oky
Posted by okydoky on May 17, 2008, at 17:34:00
In reply to Re: amineptine (survector) experience, posted by okydoky on May 13, 2008, at 13:29:15
I was so suicidal for the last few months from Lyrica and having depression to begin with and increased pain I have gotten very impatient or perhaps desperate.
I went off the added Lamictal because I got a rash and was very afraid.
Started taking Tianeptine to augment the Amineptine two days ago and am quite surprised I have been able to tolerate it.
I went off the Amineptine as I was getting no where with it this time and to see if Tianeptine by itself did anything. Hopefully I will be able to take it long enough to tell. At the very least this could inform me further as to a good direction pharmaceutically. I have been very aggressive in my treatment for Interstitial Cystitis lately, and for now somewhat successful, which has been a limiting factor in taking most of these medications in the past.
I checked everything out before I started the Amineptine but disorganized and forgetful am looking for some reassurance that the headache I am feeling today is just one of my migraines and not Amineptine withdrawal?
I said I would post progress with the Amineptine. For now I stopped taking it. I am particularly interested in agents involved in neuroplasticity. So Tianeptine and Selegiline seemed intriguing.
Anyone taking Amineptine please post your experience.
oky
This is the end of the thread.
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