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Dr. Bob is Robert Hsiung, MD,
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Posted by linkadge on August 11, 2007, at 19:56:54
Anyone have any information of whether desvenlafaxine differs to any appreciable extent from venlafaxine in terms of ratio of affinity for monoamine uptake pumps?
Venlafaxine elevated my blood pressure but was a reasonable AD. Would desvenlafaxine be any different?
Linkadge
Posted by Larry Hoover on August 11, 2007, at 20:23:55
In reply to desvenlafaxine vs. venlafaxine + uptake ratio ?, posted by linkadge on August 11, 2007, at 19:56:54
> Anyone have any information of whether desvenlafaxine differs to any appreciable extent from venlafaxine in terms of ratio of affinity for monoamine uptake pumps?
>
> Venlafaxine elevated my blood pressure but was a reasonable AD. Would desvenlafaxine be any different?
>
> LinkadgeAccording to the data I just looked at, they have virtually identical inhibition at 5-HT, and NE, but desvenlafaxine is substantially weaker at the dopamine transporter. I found no desvenlafaxine data for adrenergic/muscarinic receptors.
Lar
Posted by linkadge on August 12, 2007, at 8:47:25
In reply to Re: desvenlafaxine vs. venlafaxine + uptake ratio ? » linkadge, posted by Larry Hoover on August 11, 2007, at 20:23:55
Thanks
Linkadge
This is the end of the thread.
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