Psycho-Babble Medication Thread 684524

Shown: posts 1 to 10 of 10. This is the beginning of the thread.

 

Different SSRI's - sideeffects anyway?

Posted by sdb on September 9, 2006, at 16:06:42

A p-doc once told me if people have a sideeffect because of a ssri they will have the same sideffect on all other ssri's too. Above all he mentioned the sexual sideeffects. My limited short horrible experience of Celexa/Lexapro confirmed this although
it is not convincing because there's only the enantiomer difference.

Any other experiences or denials/consents?

 

Re: Different SSRI's - sideeffects anyway? » sdb

Posted by Racer on September 9, 2006, at 17:02:14

In reply to Different SSRI's - sideeffects anyway?, posted by sdb on September 9, 2006, at 16:06:42

I've had different s/e to different SSRIs. The sexual s/e have ranged from severe to virtually non-existent, too. In fact, about the only thing I can say has been pretty consistent for me is constipation. I've had that on every A/D except Wellbutrin and Cymbalta.

So, n of one, but I don't believe your doctor on that one. I'll look forward to seeing what others have to say...

 

Re: Different SSRI's - sideeffects anyway?

Posted by Phillipa on September 9, 2006, at 17:09:32

In reply to Re: Different SSRI's - sideeffects anyway? » sdb, posted by Racer on September 9, 2006, at 17:02:14

They were different for me. Lexapro wired me. Celexa and yes I know they're supposed to be the same med made me tired. Prozac I took three time wasn't even depressed it sent me through the roof with anxiety. Luvox I can tolerate. No side effects but no improvement either. Love phillipa

 

Re: Different SSRI's - sideeffects anyway? » sdb

Posted by yxibow on September 9, 2006, at 17:51:54

In reply to Different SSRI's - sideeffects anyway?, posted by sdb on September 9, 2006, at 16:06:42

> A p-doc once told me if people have a sideeffect because of a ssri they will have the same sideffect on all other ssri's too. Above all he mentioned the sexual sideeffects. My limited short horrible experience of Celexa/Lexapro confirmed this although
> it is not convincing because there's only the enantiomer difference.
>
> Any other experiences or denials/consents?

No, not all SSRIs are made from the same box. They hit serotonin subtransmitters with different intensity. Zoloft has a very minor dopaminergic action. If they were, they wouldn't be marketed (with the exception of Celexa/Lexapro which are just metabolites and mostly patent extenders of each other). Yes, sexual side effects are a very common one, but particular SSRIs may not have as strong an effect in that direction -- unfortunately you had it on Celexa, which some regard as having less. They will all have some side effects, dry mouth, sexual effects, minor tremor, etc.

As with all medications, one has to say, well do I want to get better with X medication, is it helping me, and do I tolerate the main side effect. If the sexual side effects get in the way, there are a host of ways of getting around this from skipping a pill for short acting SSRIs to various anti-serotonin medications such as cyproheptadine, yohimbine [caution with this one], and the like, but of course none of those are perfect either. Better living through chemistry doesn't mean better living and no side effects, alas.

-- tidings

Jay

 

Re: Different SSRI's - sideeffects anyway?

Posted by finelinebob on September 9, 2006, at 19:58:23

In reply to Different SSRI's - sideeffects anyway?, posted by sdb on September 9, 2006, at 16:06:42

I've only really tried three SSRIs.

Zoloft? Full blown manic episode ... ah, it was nice to feel happy for once. Then crash. Dry mouth all the time. Stopped it, came back later, nothing but drymouth (no main effects either).

Prozac? YAWN! No reaction of any kind. But that was after starting Wellbutrin, getting psychotic from that, starting perphenazine (about 5-10% of a normal dose for psychotics), getting zombyfied, THEN adding Prozac. My PDoc at the time knew that perphenazine and Prozac don't mix, but he thought the extremely low level of perphenazine wouldn't make it a problem. He was slowly proven wrong. But monotherapy on Prozac after that calamity, and nothing.

Paxil. ROTFLMAO! I'm sorry, I'm sure there must be some people out there for whom this med does some good, but desert mouth, extreme agitation, agoraphobia, visual hallucinations. The withdrawal was awful, but nowhere near as bad as being on it for me.

Yeah, but the sex thing was one common denominator. One.

 

Re: Different SSRI's - sideeffects anyway?

Posted by bassman on September 9, 2006, at 20:04:17

In reply to Different SSRI's - sideeffects anyway?, posted by sdb on September 9, 2006, at 16:06:42

Completely disagree-I've been on Paxil, Zoloft, Prozac, Wellbutrin, Celexa, and Lexapro. Didn't see any difference between Celexa and Lexapro-but all the other ones were VERY distinct in terms of side effects, including sexual side effects.

 

Re: Different SSRI's - sideeffects anyway?

Posted by sdb on September 10, 2006, at 12:15:01

In reply to Re: Different SSRI's - sideeffects anyway?, posted by bassman on September 9, 2006, at 20:04:17

Celexa made me tired only on 10mg. Lexapro was horrible after taking one pill. I have to say that I've never taken a drug for thirty days constantly.
Celexa seems to cause tiredness for many people whereas Prozac is probably different. I don't know.

 

Re: Different SSRI's - sideeffects anyway?

Posted by SLS on September 11, 2006, at 6:12:58

In reply to Different SSRI's - sideeffects anyway?, posted by sdb on September 9, 2006, at 16:06:42

Each SSRI has its own individual "personality" regarding side effects and overall objective experience. There is even a substantial difference between Celexa and Lexapro.


- Scott

 

Re: Different SSRI's - sideeffects anyway?

Posted by VillageInn on January 30, 2007, at 11:07:12

In reply to Re: Different SSRI's - sideeffects anyway?, posted by SLS on September 11, 2006, at 6:12:58

I've been taking Lexapro for about 22 months now and I definitely notice the constipation, insomnia, increased anxiety. I was on Zoloft a long time ago and I'm wondering if that would be better for me than Lexapro? Somehow I only remember the loss of sexual drive as the main side effect. I kieep feeling that despite taking my meds each day as prescribed, I still feel depressed.

 

Re: Different SSRI's - sideeffects anyway?

Posted by rina on February 3, 2007, at 18:28:17

In reply to Re: Different SSRI's - sideeffects anyway?, posted by VillageInn on January 30, 2007, at 11:07:12

> I've been taking Lexapro for about 22 months now and I definitely notice the constipation, insomnia, increased anxiety. I was on Zoloft a long time ago and I'm wondering if that would be better for me than Lexapro? Somehow I only remember the loss of sexual drive as the main side effect. I kieep feeling that despite taking my meds each day as prescribed, I still feel depressed.

I was on lexapro for about three years. All of a sudden, those symtoms you mentioned started for me as well. Then it just stop working. Zoloft made me gain weight and sweat all day, with insomnia.


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