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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 18 of 18. This is the beginning of the thread.
Posted by rubenstein on April 9, 2006, at 20:46:52
I am on two heavy doses of antibiotics. Can this at all affect my depression. I cry for no reason, feel anxiety in my chest, afraid to go to sleep....anybody else had a similiar experience?
rachel
Posted by SLS on April 9, 2006, at 21:05:22
In reply to antibiotics and depression, posted by rubenstein on April 9, 2006, at 20:46:52
> I am on two heavy doses of antibiotics. Can this at all affect my depression. I cry for no reason, feel anxiety in my chest, afraid to go to sleep....anybody else had a similiar experience?
> rachelI found erythromycin to be somewhat depressing.
- Scott
Posted by Phillipa on April 9, 2006, at 23:54:56
In reply to Re: antibiotics and depression, posted by SLS on April 9, 2006, at 21:05:22
Funny after 24 hours I used to feel wonderful on all antibiotics strange. Love Phillipa
Posted by Caedmon on April 10, 2006, at 0:49:46
In reply to Re: antibiotics and depression, posted by Phillipa on April 9, 2006, at 23:54:56
Maybe, I'm not sure. I'm on minocycline. I was on a lot of other things before that, Septra and doxycycline, erythromycin, I think that's it. For acne. Yes, I've been very depressed on them but I never figured there was a causal relationship (I've always been depressed).
- C
Posted by yxibow on April 10, 2006, at 4:58:03
In reply to antibiotics and depression, posted by rubenstein on April 9, 2006, at 20:46:52
> I am on two heavy doses of antibiotics. Can this at all affect my depression. I cry for no reason, feel anxiety in my chest, afraid to go to sleep....anybody else had a similiar experience?
> rachelDepends on the antibiotic... Biaxin (clarithromycin), and some related antibiotics can cause psychiatric problems. I didn't react very well to it. Of course, if its life threatening, if one can bear through it, the antibiotic is obviously best. But there are choices in less severe instances that your doctor could make.
Posted by valene on April 10, 2006, at 9:01:30
In reply to antibiotics and depression, posted by rubenstein on April 9, 2006, at 20:46:52
Yes antibiotics can cross the blood-brain-barrier and cause anxiety, depression, etc. I know that the quinolones are some of the worst culprits. I will not touch them. Also I was on Z-pak (azythromycin) for 2 courses due to an infected root canal and I suffered increased anxiety, depression insomnia.
The prescribing information for azythromycin confirms that it can cause anxiety, insomnia, etc.
The safest A/B's are probably some of the older ones such as amoxicillin, pen vee K, etc. in my opinion only.
Val
Posted by ed_uk on April 10, 2006, at 16:36:33
In reply to antibiotics and depression, posted by rubenstein on April 9, 2006, at 20:46:52
The quinolones are the most notorious. Ciprofloxacin, levofloxacin etc.
Ed
Posted by mgm on April 11, 2006, at 20:14:50
In reply to Re: antibiotics and depression » rubenstein, posted by ed_uk on April 10, 2006, at 16:36:33
> The quinolones are the most notorious. Ciprofloxacin, levofloxacin etc.
>
> EdI second that witht the quinolones. I suffer from depression and my husband doesn't. My husband took a course of levofloxacin and thought he was losing his mind. The pharmacist told him that it was a side affect of the medicine.
MGM
Posted by Phillipa on April 11, 2006, at 20:30:38
In reply to Re: antibiotics and depression, posted by mgm on April 11, 2006, at 20:14:50
Levoquin made me really crazy. I didn't even know an antibiotic could. Love Phillipa
Posted by rubenstein on April 11, 2006, at 20:43:54
In reply to Re: antibiotics and depression » mgm, posted by Phillipa on April 11, 2006, at 20:30:38
> That is what I am taking
Thanks for the input everyone
I knew it wasn't just chance that I was feeling so wack
rachelLevoquin made me really crazy. I didn't even know an antibiotic could. Love Phillipa
Posted by ed_uk on April 12, 2006, at 10:33:33
In reply to Re: antibiotics and depression, posted by rubenstein on April 11, 2006, at 20:43:54
Is levofloxacin (Levaquin) used a lot in the US? In the UK it's only popular in hospitalised patients with serious/resistant infections. It's rarely used outside hospital. GPs prefer older antibiotics like amoxicillin.
Ed
Posted by Phillipa on April 12, 2006, at 11:12:11
In reply to Levaquin, posted by ed_uk on April 12, 2006, at 10:33:33
When I called and told the doctor was was happening they acted like I was crazy and it was just as a precaution for a flu like illness in an out pt facility. Love PJ O
Posted by yxibow on April 13, 2006, at 1:04:28
In reply to Re: Levaquin » ed_uk, posted by Phillipa on April 12, 2006, at 11:12:11
> When I called and told the doctor was was happening they acted like I was crazy and it was just as a precaution for a flu like illness in an out pt facility. Love PJ O
Antibiotics are overused in this country -- and some older ones are quite overused in China and other countries.
This timeline, which I posted before, gives a fascinating inlook into the history of antibiotics (not complete but fairly accurate)
http://en.wikipedia.org/wiki/Timeline_of_antibiotics
This image is not for the faint of heart, linezolid (Zyvox) (IV)
http://www.zyvox.com/index.asp?hcp=true
One of the two antibiotics of last resort. The last one was made in 2001 for the EU and 2004 for the US, Ketek.
"Since 1998, only 10 new antibiotics have been approved by FDA—two of which are truly novel (i.e., have a new target of action, with no cross-resistance with other antibiotics)."
-- Infectious Disease Society of AmericaGSK is exepected to market retapamulin this year.
Two more near last resorts also (IV):
Tygacil (tigecycline) was approved last year, another first in class
Cubicin (daptomycin)
But the pipeline is small in comparison to other drugs, and it is a growing concern at hospitals. Some estimate over a billion would have to be invested in truly novel antibiotics.
And except for HIV and other sexually/human transmitted diseases such as Hepatits, vaccine research also is in vast need of a pipeline.
Tamiflu has been approved for H5N1, bird flu, though we do not know its full effectiveness.
Of course this is the psych board, so we're getting in the health range... but its an important thing to know.
Posted by yxibow on April 13, 2006, at 13:21:13
In reply to Re: Levaquin, posted by yxibow on April 13, 2006, at 1:04:28
> And except for HIV and other sexually/human transmitted diseases such as Hepatits, vaccine research also is in vast need of a pipeline.That's Hepatitis (and Herpes too)... grr.. I always spell correct.. anyhow... you get the drift.
Posted by ed_uk on April 13, 2006, at 16:01:36
In reply to Re: Levaquin, posted by yxibow on April 13, 2006, at 1:04:28
Hi Yxi
Antibiotics are overused by GPs in the UK. Thankfully, only a small range of old antibiotics are widely prescribed, thus limiting the development of resistance to new antibiotics.
Ed
Posted by jules354 on June 2, 2006, at 15:52:04
In reply to Re: antibiotics and depression, posted by rubenstein on April 11, 2006, at 20:43:54
Does anyone know if Flagyl can trigger depression or anxiety? I've been feeling really out of it, but I dont' know if it's the Flagyl or just life.
take care,
jules
Posted by Caedmon on June 4, 2006, at 23:04:12
In reply to Re: antibiotics and depression, posted by jules354 on June 2, 2006, at 15:52:04
My Pocket PDR lists depression as a possible side effect for flagyl. Also:
http://www.rxlist.com/cgi/generic/metronidaz_ad.htm- Chris
Posted by Phillipa on June 4, 2006, at 23:51:26
In reply to Re: antibiotics and depression, posted by jules354 on June 2, 2006, at 15:52:04
I didn't take flagyl. Took Biaxin long acting and Rocephin but the one the helped the most was docycycline. Love Phillipa
This is the end of the thread.
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