Shown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by DavidLA on February 13, 2006, at 20:48:36
When do you take Nardil?
I take it all (45 mg) in the morning and I still often have insomnia at night. I've tried to switch to taking it in the evenings, but it was very difficult and I went back to taking it the morning. I'm wondering if anyone has figured out a dosing regiment that reduces their insomnia.
Thanks,
DLA
Posted by SLS on February 13, 2006, at 23:16:05
In reply to Nardil dosing times to reduce insomnia?, posted by DavidLA on February 13, 2006, at 20:48:36
> When do you take Nardil?
>
> I take it all (45 mg) in the morning and I still often have insomnia at night. I've tried to switch to taking it in the evenings, but it was very difficult and I went back to taking it the morning. I'm wondering if anyone has figured out a dosing regiment that reduces their insomnia.
>
> Thanks,
> DLA
I doubt the insomnia is dependent upon dosing schedule. Unlike Parnate, which has a short half-life and amphetamine-like properties, Nardil produces a more consistent blood level. It hangs around all day long. The insomnia is probably due to the inhibition of MAO rather than a direct stimulant effect of the Nardil or its metabolites. For this reason, it really wouldn't matter what time you took it once monoamine oxidase inhibition is established.You may have little choice but to add a hypnotic drug to help you sleep.
Nardil + sleep deprivation makes a powerful combination for someone who is bipolar. It very often induces mania.
- Scott
Posted by tepiaca on February 14, 2006, at 14:57:06
In reply to Nardil dosing times to reduce insomnia?, posted by DavidLA on February 13, 2006, at 20:48:36
Hi David I agree with Scott . I was on Nardil
for 2 years and it seems that the best way to
combat Nardil insomnia is to take it together
with an hypnotic.
I got bad insomnia at 60mg , which the only
thing that could help sleep was Seroquel.
Ambien poop out very fast.
At 45mg I could sleep with my 0.5 ClonazepamGood luck
Posted by ed_uk on February 14, 2006, at 15:19:35
In reply to Nardil dosing times to reduce insomnia?, posted by DavidLA on February 13, 2006, at 20:48:36
Hi David
>I've tried to switch to taking it in the evenings, but it was very difficult.....
What happened?
Ed
Posted by gardenergirl on February 14, 2006, at 15:31:20
In reply to Re: Nardil dosing times to reduce insomnia? » DavidLA, posted by ed_uk on February 14, 2006, at 15:19:35
I spread my doses out during the day: One tablet in the a.m. about 8ish, one and a half (at the moment) at about 2:00, and then one last tablet at about 10:00.
I have insomnia a great deal, too--both difficulty initiating sleep, but also frequent waking if I do manage to get to sleep. I am using Ambien with great success to counter this.
About the only thing I've noticed related to whenI take it is that I seem to start eating sweets about an hour after I take a dose. I never noticed this before, as far as the timing, but I wonder if there is a connection. I'm going to try to monitor this and to have a plan for a substitute/healthier sweet available to see if that helps.
Good luck with figuring out how to combat the insomnia. It's such a strain.
gg
Posted by DavidLA on February 14, 2006, at 20:57:39
In reply to Re: Nardil dosing times-- new? related to cravings, posted by gardenergirl on February 14, 2006, at 15:31:20
Yeah, I have the same cravings for sweets. I think that compulsion is a big part of the reason why weight gain is so common with Nardil. I binge nightly on "low-fat" chocolate chip cookies. I've been on/off Nardil for years and I've never found a way to minimize the compulsion to eat large amounts of carbs/sweets.
> About the only thing I've noticed related to whenI take it is that I seem to start eating sweets about an hour after I take a dose. I never noticed this before, as far as the timing, but I wonder if there is a connection. I'm going to try to monitor this and to have a plan for a substitute/healthier sweet available to see if that helps.
Posted by DavidLA on February 14, 2006, at 21:16:10
In reply to Re: Nardil dosing times to reduce insomnia? » DavidLA, posted by ed_uk on February 14, 2006, at 15:19:35
My body is so used to taking my whole dose in morning, that when I tried to switch to later in the evening I quickly became depressed and my body clock got all out of wack. I know I can make the switch, but I was curious to see what other people's experiences were. The feedback I'm getting is that changing my dosing schedule probably won't minimize my insomnia.
On related topic, do any Nardil users not feel like going to sleep at a "normal" time at night? I take 75 mg Trazadone at bedtime to sleep, which works fairly well. However, Nardil makes me *not* want to even try to go to sleep until 2 AM on most nights. It really destroys my natural circadian rhythm. I often only get 5 hours sleep -- yet I can function the next day. I know I should get more sleep, but Nardil seems to make want *less* sleep. Anyone have this experience? Any ways to moderate this compulsion to stay up too late?
DLA
> Hi David
>
> >I've tried to switch to taking it in the evenings, but it was very difficult.....
>
> What happened?
>
> Ed
Posted by jedi on February 17, 2006, at 2:36:06
In reply to Re: Nardil (staying up too late/circadian rhythm), posted by DavidLA on February 14, 2006, at 21:16:10
Hi,
I'm off Nardil now thanks to (I believe) high doses of Omega-3 fatty acids (2400mg EPA & 2000mg DHA daily) I seemed to always go to bed very late when taking 90+mg of Nardil daily. A lot of times I would get four or five hours sleep per night, then crash with a nap at five in the afternoon. If you are napping (pretty common on this med), it kind of becomes a viscious cycle of two sleep periods per day. Dosage timing made no difference for me. I always slept much less while on Nardil. Atypical depression, for which Nardil is the gold standard, would sometimes have me sleeping fourteen to sixteen hours per day. Nardil fixed that problem. If it wasn't for the common side effect of extreme weight gain, Nardil would be a perfect medication for my atypical depression and social phobia.
Jedi> My body is so used to taking my whole dose in morning, that when I tried to switch to later in the evening I quickly became depressed and my body clock got all out of wack. I know I can make the switch, but I was curious to see what other people's experiences were. The feedback I'm getting is that changing my dosing schedule probably won't minimize my insomnia.
>
> On related topic, do any Nardil users not feel like going to sleep at a "normal" time at night? I take 75 mg Trazadone at bedtime to sleep, which works fairly well. However, Nardil makes me *not* want to even try to go to sleep until 2 AM on most nights. It really destroys my natural circadian rhythm. I often only get 5 hours sleep -- yet I can function the next day. I know I should get more sleep, but Nardil seems to make want *less* sleep. Anyone have this experience? Any ways to moderate this compulsion to stay up too late?
>
> DLA
>
> > Hi David
> >
> > >I've tried to switch to taking it in the evenings, but it was very difficult.....
> >
> > What happened?
> >
> > Ed
>
>
Posted by DavidLA on February 17, 2006, at 20:36:55
In reply to Re: Nardil (staying up too late/circadian rhythm) » DavidLA, posted by jedi on February 17, 2006, at 2:36:06
Interesting, can you tell me about your Omega-3 experience? Is that really working for you as an alternative to Nardil for depression/social phobia?
I recently started taking a low dose of Omega-3 (1000mg EPA/DHA) and haven't noticed anything. I'm a long-term Nardil user, but would *love* to get off of it if I could find something else that worked even half as well.
Thanks,
DLA> Hi,
> I'm off Nardil now thanks to (I believe) high doses of Omega-3 fatty acids (2400mg EPA & 2000mg DHA daily) I seemed to always go to bed very late when taking 90+mg of Nardil daily. A lot of times I would get four or five hours sleep per night, then crash with a nap at five in the afternoon. If you are napping (pretty common on this med), it kind of becomes a viscious cycle of two sleep periods per day. Dosage timing made no difference for me. I always slept much less while on Nardil. Atypical depression, for which Nardil is the gold standard, would sometimes have me sleeping fourteen to sixteen hours per day. Nardil fixed that problem. If it wasn't for the common side effect of extreme weight gain, Nardil would be a perfect medication for my atypical depression and social phobia.
> Jedi
>
> > My body is so used to taking my whole dose in morning, that when I tried to switch to later in the evening I quickly became depressed and my body clock got all out of wack. I know I can make the switch, but I was curious to see what other people's experiences were. The feedback I'm getting is that changing my dosing schedule probably won't minimize my insomnia.
> >
> > On related topic, do any Nardil users not feel like going to sleep at a "normal" time at night? I take 75 mg Trazadone at bedtime to sleep, which works fairly well. However, Nardil makes me *not* want to even try to go to sleep until 2 AM on most nights. It really destroys my natural circadian rhythm. I often only get 5 hours sleep -- yet I can function the next day. I know I should get more sleep, but Nardil seems to make want *less* sleep. Anyone have this experience? Any ways to moderate this compulsion to stay up too late?
> >
> > DLA
> >
> > > Hi David
> > >
> > > >I've tried to switch to taking it in the evenings, but it was very difficult.....
> > >
> > > What happened?
> > >
> > > Ed
> >
> >
>
>
Posted by jedi on February 17, 2006, at 21:22:14
In reply to Re: Nardil (Omega-3 as alternative), posted by DavidLA on February 17, 2006, at 20:36:55
DLA,
Since this discussion will be redirected to the Alternative board, I'll save Dr. Bob the trouble. If my experiences with Omega-3 fatty acids are any indication, there may be a day when it is not an alternative, but perhaps the medication of choice for atypical depression. Seems to take a couple of months at high dosages (at least 1000mg of EPA) for the effects on depression to kick in. As a long term Nardil user, I am becoming a believer in this particular alternative treatment. I still take 1mg clonazepam for the social anxiety.
Best of Luck,
JediLinks:
http://www.dr-bob.org/babble/alter/20051208/msgs/598560.html
http://www.dr-bob.org/babble/alter/20060130/msgs/606178.html
> Interesting, can you tell me about your Omega-3 experience? Is that really working for you as an alternative to Nardil for depression/social phobia?
>
> I recently started taking a low dose of Omega-3 (1000mg EPA/DHA) and haven't noticed anything. I'm a long-term Nardil user, but would *love* to get off of it if I could find something else that worked even half as well.
>
> Thanks,
> DLA
>
Posted by Dr. Bob on February 18, 2006, at 4:24:19
In reply to Re: Nardil (Omega-3 as alternative) » DavidLA, posted by jedi on February 17, 2006, at 21:22:14
This is the end of the thread.
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