![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by qbsbrown on January 14, 2006, at 3:24:04
I have reminents of panic disorder, GAD, OCD, depression, and minor BPII.
ONE BEER, and this all goes away, like a new person,a human and myself again.
I've tried paxil, lexapro, celexa, AEDs, benzos (xanax works well)(klono depresses).
Am i bound to try an SSNRI? What neurotransmitters are being effected from one drink of alcohol, aside from GABA and CNS depression? Benzos do that, and they don't make me feel well.
Thanks for advice, guesses.
Posted by blueberry on January 14, 2006, at 6:19:55
In reply to What med will work for me, given this note????????, posted by qbsbrown on January 14, 2006, at 3:24:04
All of the neurotransmitters are intricately linked in ways that no one can really explain with current science. But, from what you describe, it sounds like dopamine might be a major player, with norepinephrine, serotonin, and gaba as secondary players.
The beer causes a rush of dopamine. Xanax is a unique benzo in that at low doses it also stimulates dopamine, whereas the others or higher doses squash out the dopamine. The SSRIs and AEDs are probably squashing out the dopamine and that could be why they didn't help you much.
Med choices are endless, and predictions don't often work. Some medications that work primarily on serotonin also have significant dopamine enhancing effects, such as prozac or cymbalta or zyprexa or a combination. Zyprexa also has some affinity for gaba.
On the natural side, St Johns Wort fits...reuptake inhibition of serotonin, dopamine, norepinephrine, and GABA...anti-anxiety and antidepressant. Amino acids tyrosine, dl-phenylalanine, and calming ones like gaba+glycine+taurine combos at the health food store. Easy to experiment with and only a few days trial is needed with each to see.
But in the end, all medications are much more complex than anyone knows, so it is very hard to make any predictions. I saw a science show on TV a while ago that showed how beer works on the brain, and the primary thing that first happens with it is a flood of dopamine, which is later negated by the sedation.
> I have reminents of panic disorder, GAD, OCD, depression, and minor BPII.
>
> ONE BEER, and this all goes away, like a new person,a human and myself again.
>
> I've tried paxil, lexapro, celexa, AEDs, benzos (xanax works well)(klono depresses).
>
> Am i bound to try an SSNRI? What neurotransmitters are being effected from one drink of alcohol, aside from GABA and CNS depression? Benzos do that, and they don't make me feel well.
>
> Thanks for advice, guesses.
Posted by qbsbrown on January 14, 2006, at 17:54:32
In reply to Re: What med will work for me, given this note????????, posted by blueberry on January 14, 2006, at 6:19:55
Wouldn't that mean that Wellbutrin would work well? Albeit it would be horrible for my anxiety, OCD, and panic attacks.
I'm gonna give Cymbalta a go. I'd rather skip the sexual side-effects from prozac.
Seemed to be the choice of my doc, and i never told him about the beer making me feel absolutely normal (but knows about serious past alcohol abuse).
Now my biggest challenge is weaning off of Klonopin, i dispise it.
Posted by Phillipa on January 14, 2006, at 20:57:07
In reply to Re: What med will work for me, given this note????????, posted by qbsbrown on January 14, 2006, at 17:54:32
Wow beer always made me feel normal too. Only needed .5 of xanax and always felt great! Wellbutrin on the other hand made me hypomanic in a week. And I couldn't handle cymbalta due to anxiety issues. I take valium l5-20mg at night to sleep but lately it seems to be backfiring on me and causing me to wake up with rapid pulse sweating , anxiety. I long for the days of drinking beer. Fondly, Phillipa
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.