![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by alienatari on February 7, 2005, at 1:47:01
Hey all. I am also on Zyprexa and Depakote but neither make me tired. Since starting parnate i always get this afternoon tiredness. My doctor has increased my Parnate to 30mgs now, which is still a low dose, and I am even more tired.
Today I woke up at about 8:30 am after having around 10 1/2 hours sleep. I felt good. Took my parnate, by 12pm I had to go lay down and have a rest. Its now 6:30pm and I am ready for another rest. I cant function like this! Ive tried 17 antidepressants and I dont know whether I should stay on Parnate and put up with this and the other side effects im getting (anxiety, nausea, dizzyness, sexual dysfunction .etc) or try a new one or maybe just stick to Depakote and Zyprexa on its own. I was fine before taking Seroquel and Depakote with no antidepressant, i am Bipolar and was in remission from mania and from depression for quite a while but that ended when I stopped taking seroquel (had to stop it because it was making my throat close up and made it hard to breathe).
I am unsure if the antidepressant effects ive experienced from Parnate were from Parnate itself or from Zyprexa because I started them both around the same period of time.
Also, im considering trying Stablon (im in Australia and the Drug is made in France, but can be legally imported by an MD to Australia). It works on seratonin but is not an SSRI. It does not have sexual dysfunction as a listed side effect and Is apparently great for anxiety and OCD (i also have anxiety and OCD). I should also mention that I have paranoia, but I believe my paranoia is linked to my OCD rather than it being psychotic as SSRI's have helped with my paranoia and OCD but nothing except the moodstabalisers+antipsychotic combo's has given me any releif from the depression I get when I cycle.
Anyway sorry for such a long post and thank you for your time. Any information anyone has would be greatly appreciated. Any drug reccommendations too would also be greatly appreciated, even if they are not in Australia, just as long as my Pdoc can import them.
p.s. This is rather interesting, my doc phoned Alphapharm, who are the people who make Selegiline in Australia and they said that "EmSam will only be for people with Parkinsons disease and will have no use for depression" which is obviously not true. I guess because they have nothing to gain or they are not up-to-date with medications they dont make they spread information that is wrong.
Thanks again and take care.
Posted by Smeegle on February 7, 2005, at 3:22:02
In reply to So tired. So very very Tired (Parnate) and Stablon, posted by alienatari on February 7, 2005, at 1:47:01
I gained 50 lbs in two months on Depakote! (and it didn't even help...lol). I swear I ate like six pregnant women, I was ravenous all the time.
Keep and eye on that. It's well known to cause weight gain. And if you need to gain weight...more power to ya!
Smeegs
Posted by alienatari on February 7, 2005, at 3:36:15
In reply to Re: So tired. So very very Tired (Parnate) and Stablon, posted by Smeegle on February 7, 2005, at 3:22:02
Thats terrible. Ahh gosh, no i dont need weight gain!!!! lol
Thankfully Depakote has never caused weight gain in me. ive been on it for years now.
Take care.
Posted by Optimist on February 7, 2005, at 10:19:57
In reply to So tired. So very very Tired (Parnate) and Stablon, posted by alienatari on February 7, 2005, at 1:47:01
> Hey all. I am also on Zyprexa and Depakote but neither make me tired. Since starting parnate i always get this afternoon tiredness. My doctor has increased my Parnate to 30mgs now, which is still a low dose, and I am even more tired.
>
> Today I woke up at about 8:30 am after having around 10 1/2 hours sleep. I felt good. Took my parnate, by 12pm I had to go lay down and have a rest. Its now 6:30pm and I am ready for another rest. I cant function like this! Ive tried 17 antidepressants and I dont know whether I should stay on Parnate and put up with this and the other side effects im getting (anxiety, nausea, dizzyness, sexual dysfunction .etc) or try a new one or maybe just stick to Depakote and Zyprexa on its own. I was fine before taking Seroquel and Depakote with no antidepressant, i am Bipolar and was in remission from mania and from depression for quite a while but that ended when I stopped taking seroquel (had to stop it because it was making my throat close up and made it hard to breathe).
>
> I am unsure if the antidepressant effects ive experienced from Parnate were from Parnate itself or from Zyprexa because I started them both around the same period of time.
>
> Also, im considering trying Stablon (im in Australia and the Drug is made in France, but can be legally imported by an MD to Australia). It works on seratonin but is not an SSRI. It does not have sexual dysfunction as a listed side effect and Is apparently great for anxiety and OCD (i also have anxiety and OCD). I should also mention that I have paranoia, but I believe my paranoia is linked to my OCD rather than it being psychotic as SSRI's have helped with my paranoia and OCD but nothing except the moodstabalisers+antipsychotic combo's has given me any releif from the depression I get when I cycle.
>
> Anyway sorry for such a long post and thank you for your time. Any information anyone has would be greatly appreciated. Any drug reccommendations too would also be greatly appreciated, even if they are not in Australia, just as long as my Pdoc can import them.
>
> p.s. This is rather interesting, my doc phoned Alphapharm, who are the people who make Selegiline in Australia and they said that "EmSam will only be for people with Parkinsons disease and will have no use for depression" which is obviously not true. I guess because they have nothing to gain or they are not up-to-date with medications they dont make they spread information that is wrong.
>
> Thanks again and take care.Alienatari,
I've heard the afternoon tiredness thing may be related to dips in blood pressure. One way to increase your blood pressure is to increase your salt intake. I've heard that's helped with the afternoon tiredness for some. Others have used amphetamine to increase both their blood pressure and energy.
How long have you been on Parnate for? I know many say the afternoon tiredness goes away after a few months, once your body gets used to the drug. Has it been very long?
Brian
Posted by cubbybear on February 7, 2005, at 10:39:56
In reply to Re: So tired. So very very Tired (Parnate) and Sta » alienatari, posted by Optimist on February 7, 2005, at 10:19:57
I agree with Optimist. The afternoon fatigue is frequently just for a short time, and I myself have always added salt to my food to counteract the hypotensive effect of Parnate.
The only thing I must caution you about is DO NOT TAKE STABLON WITH A PARNATE. I live in Thailand and just learned about Stablon last week. Checked it out further and the contraindications clearly state, "Not to be used with MAOIs." cubbybear
Posted by alienatari on February 7, 2005, at 17:13:22
In reply to Re: So tired. So very very Tired (Parnate) and Sta, posted by cubbybear on February 7, 2005, at 10:39:56
I know not to take it with Parnate, i was thinking about stopping parnate and taking that instead but thanks for the warning. I have been on Parnate for a while now i dont think the tiredness will go :( its been about 3 months ive been on it now.
take care.
Posted by Maxime on February 7, 2005, at 18:48:49
In reply to Re: So tired. So very very Tired (Parnate) and Sta » alienatari, posted by Optimist on February 7, 2005, at 10:19:57
Parnate exhausted me BUT it still rid me of my depression. And I would try to explain to my doctor that it was not the same as sedation. I didn't feel sleepy, I felt exhausted. I felt like if I did not lie down I would probably fall down. That's why I had the Adderall added on.
So it may be the Parnate that is causing it. When I was on Zyprexa that just knocked me out ... sedation at it's worst!
Maxime
Posted by alienatari on February 8, 2005, at 6:42:07
In reply to Re: So tired. So very very Tired (Parnate) and Sta, posted by Maxime on February 7, 2005, at 18:48:49
I dont think my docs too keen on me adding stimulants :(
I seem to have an atypical response to Zyprexa. It doesnt knock me out at all.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.