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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 24 of 24. This is the beginning of the thread.
Posted by Dinah on January 24, 2005, at 22:35:22
I hate SSRI's.
I hate SSRI's.
I hate SSRI's.
Only a few weeks on Luvox and here it is time to take it and my ears are ringing. If I forget for a few more hours (which is admittedly hard to do with the blasted ringing ears) I won't be able to sleep for the head buzzing.
I'm going to quit taking the blasted stuff. I swear. It just doesn't do enough for me to justify the withdrawal. And ear ringing and head buzzing. Oh, and the increased IBS.
It's a wonder drug all right.
Posted by mike13 on January 24, 2005, at 22:57:34
In reply to I hate SSRI's. I hate SSRI's., posted by Dinah on January 24, 2005, at 22:35:22
> I hate SSRI's.
>
> I hate SSRI's.
>
> I hate SSRI's.
>Yup me to.
Posted by Michael Bell on January 24, 2005, at 23:10:54
In reply to I hate SSRI's. I hate SSRI's., posted by Dinah on January 24, 2005, at 22:35:22
>What are you taking Luvox for? By the way, I tried Prozac and Paxil for social phobia (both sucked), and my IBS also increased.
I hate SSRI's.
>
> I hate SSRI's.
>
> I hate SSRI's.
>
> Only a few weeks on Luvox and here it is time to take it and my ears are ringing. If I forget for a few more hours (which is admittedly hard to do with the blasted ringing ears) I won't be able to sleep for the head buzzing.
>
> I'm going to quit taking the blasted stuff. I swear. It just doesn't do enough for me to justify the withdrawal. And ear ringing and head buzzing. Oh, and the increased IBS.
>
> It's a wonder drug all right.
Posted by Dinah on January 24, 2005, at 23:19:09
In reply to Re: I hate SSRI's. I hate SSRI's. » Dinah, posted by Michael Bell on January 24, 2005, at 23:10:54
I originally took it for OCD for four years, then went off. It's been four years off and I was pressured to start taking it again, this time for depression.
As AD's go, Luvox was the only one I could tolerate without getting too agitated. But I hate it. I really really do.
And I'm on the lowest possible dose without breaking up the tablets.
Posted by Ritch on January 25, 2005, at 0:27:47
In reply to I hate SSRI's. I hate SSRI's., posted by Dinah on January 24, 2005, at 22:35:22
> I hate SSRI's.
>
> I hate SSRI's.
>
> I hate SSRI's.
>
> Only a few weeks on Luvox and here it is time to take it and my ears are ringing. If I forget for a few more hours (which is admittedly hard to do with the blasted ringing ears) I won't be able to sleep for the head buzzing.
>
> I'm going to quit taking the blasted stuff. I swear. It just doesn't do enough for me to justify the withdrawal. And ear ringing and head buzzing. Oh, and the increased IBS.
>
> It's a wonder drug all right.Hi Dinah!,
Most antidepressants that I've ever taken seem to cause tinnitus (ear-ringing). I'm not sure why (can someone explain the mechanism?). I don't think the SSRI's have a monopoly on that side effect cause I got it from doxepin and WB. I never got "head-buzzing" from *withdrawing* doxepin or WB though... Mitch
Posted by Bill LL on January 25, 2005, at 7:51:56
In reply to I hate SSRI's. I hate SSRI's., posted by Dinah on January 24, 2005, at 22:35:22
Have you tried duloxetine (cymbalta)? I have not but I think that it causes less agitation for most people.
Posted by Dinah on January 25, 2005, at 9:31:49
In reply to Re: I hate SSRI's. I hate SSRI's., posted by Bill LL on January 25, 2005, at 7:51:56
Hmmm. Does it affect norepinephrine? I'm pretty sure I'm going to have to call my pdoc today because I feel itchy, crawly, jumpy which is always a very very bad sign for me with AD's. I don't understand why it's doing this at 50 mg when I used to be able to tolerate 300 mg.
If there is a good nonagitating alternative, I'm game to try it.
Posted by Dinah on January 25, 2005, at 9:35:35
In reply to Re: I hate SSRI's. I hate SSRI's. » Dinah, posted by Ritch on January 25, 2005, at 0:27:47
Hey Mitch!
How are you doing? Have you found a combination that works for you? I haven't read the meds board for a donkey's age, and have fallen behind on everyone's life.
I hate med trials. Each one seems to open whole new doors of experience. That's why I went back to an old tried and true only to find some new surprises along with the same old annoyances.
Posted by Dinah on January 25, 2005, at 9:37:34
In reply to I hate SSRI's. I hate SSRI's., posted by Dinah on January 24, 2005, at 22:35:22
Could this be behind my recent muscle spasms and jaw clenching as well? I wonder if the generic isn't equivilant to my good old Luvox.
Posted by Dinah on January 25, 2005, at 10:06:02
In reply to Cymbalta » Bill LL, posted by Dinah on January 25, 2005, at 9:31:49
I can't take norepinephrine. :( It induces hypomania. And not the good sort.
Posted by Kenny Koala on January 25, 2005, at 10:58:48
In reply to Re: I hate SSRI's. I hate SSRI's., posted by Bill LL on January 25, 2005, at 7:51:56
Posted by Dinah on January 25, 2005, at 11:28:15
In reply to Tried Clomipramine or Amitriptyline? (nm), posted by Kenny Koala on January 25, 2005, at 10:58:48
Carbon copy of Effexor in my reaction. :(
Are the others any different?
Posted by Kenny Koala on January 25, 2005, at 11:49:53
In reply to Re: Tried Nortryptaline. » Kenny Koala, posted by Dinah on January 25, 2005, at 11:28:15
> Carbon copy of Effexor in my reaction. :(
>
> Are the others any different?
>TCA's differ greatly from each other except they are nearly all moderate to good norepinephrine reuptake inhibitors which appears to be a bad thing for you after reading your other posts.
Posted by ed_uk on January 25, 2005, at 11:51:38
In reply to Re: Tried Nortryptaline. » Dinah, posted by Kenny Koala on January 25, 2005, at 11:49:53
Hi,
Dinah, what dose of fluvoxamine do you take?
Do you take it once daily or twice daily?
Do your ears ring all day long or just sometimes?Ed.
Posted by Ritch on January 25, 2005, at 12:31:36
In reply to Re: I hate SSRI's. I hate SSRI's. » Ritch, posted by Dinah on January 25, 2005, at 9:35:35
> Hey Mitch!
>
> How are you doing? Have you found a combination that works for you? I haven't read the meds board for a donkey's age, and have fallen behind on everyone's life.
>
> I hate med trials. Each one seems to open whole new doors of experience. That's why I went back to an old tried and true only to find some new surprises along with the same old annoyances.
Hi Dinah,Actually I'm doing rather well. I had been experiencing some racing thoughts and unusual hyperactivity recently and I checked my mood charting from last year, and it looks like my Nov/Dec seasonal depression has ended-yay! Wow, it ended just three-four days different from last years', what a pattern huh? But, I had to boost my Depakote up a tad and hold it there at the higher dose and everything is settling down and my head is getting quieter (whew!). So, my current combo is Depakote 375mg + Clonazepam .5-1.0 (occasional) + Neurontin 100hs + teeny tiny bit of Celexa every other day or so .3mg + 5mg of Stratterra when my cycle hits the low spot (couple of days in a row). Also supplement wise I'm on 1.5G fishoil + Folic Acid. Bottom line: Very little use of AD whatsoever and I feel more stable than ever.
"Tried and True". Yes, I had a dissapointing experience with a retrial of Prozac after having been on it for seven years, it just didn't "feel" the same at all! Interesting that you are talking about Luvox. I was thinking about asking my pdoc for a few fluvoxamine tablets to whittle on and use instead of Celexa.. hoping I could sleep better on it instead. But strong serotonergic AD's trigger this yin/yang thing with me that must have to do with my bipolar: They settle down one aspect of anxiety, but they turn around and add an agitating aspect back in. I suppose one could argue that my "serotonin receptors aren't desensitized enough because I don't take a high enough dose for a long enough time", BUT if I attempt that strategy I start cycling like a mad dog.
Is the Luvox induced tinnnitus a continuous thing, or is it only occasional? I never got a continuous ringing on AD's, just an occasional, "WHOAH, can't hear crap!" thing. If it is only occasional it might be worth it if the Luvox is helping otherwise. Does it seem to be helping the target symptoms?
good luck with retrial-- Mitch
Posted by SLS on January 25, 2005, at 13:30:24
In reply to I hate SSRI's. I hate SSRI's., posted by Dinah on January 24, 2005, at 22:35:22
> I hate SSRI's.
>
> I hate SSRI's.
>
> I hate SSRI's.
>
> Only a few weeks on Luvox...
Why was Luvox chosen?- Scott
Posted by Dinah on January 25, 2005, at 16:51:02
In reply to Re: Luvox, posted by ed_uk on January 25, 2005, at 11:51:38
I'm only at 50 mg, at bedtime. I thought it was just as it approached doseage time that my ears rang, but they did it a few minutes ago, so maybe not. I'm going to stop the darn stuff. I don't notice any benefit.
Posted by Dinah on January 25, 2005, at 16:57:47
In reply to Re: I hate SSRI's. I hate SSRI's. » Dinah, posted by Ritch on January 25, 2005, at 12:31:36
I'm so glad for you! My father's depression followed a very predictable pattern from one year to the next, but I think it was more situational than anything else. It must help to have a handle on what's going to happen.
My core meds regimen doesn't sound too different from yours. I'm up to 375 mg Depakote (as much for migraines as anything), 1 mg Klonopin, and Risperdal for those superagitated times when Klonopin isn't enough. I'm trying supplementing with calcium/magnesium and fish oil, though I'm still at the cautious easily scared stage with them.
I don't notice any difference at all on the Luvox. I think I've gotten a bit agitated the last couple of day, itchy crawly jumpy, but that may be a coincidence. I know the ear ringing isn't. Or the head buzzing. I remember those too well. The head buzzing is only if I forget a dose. The ear ringing is off and on toward the end of the day approaching doseage time. If I'm late taking my meds it gets really distracting. I could probably do away with it if I increased the dose and took it twice a day. But since I don't see any benefit, I don't think I'll ask to do that. I think I'll ask to get off the darn stuff.
Posted by Dinah on January 25, 2005, at 17:00:31
In reply to Re: I hate SSRI's. I hate SSRI's. » Dinah, posted by SLS on January 25, 2005, at 13:30:24
Hey Scott!!
Well, this time I asked for it when my therapist started pressuring me to take an AD. I do so badly on so many of them, and Luvox was the least troublesome.
When I started it eight years ago (I've been off for four after being on for four) it was probably the obvious choice for a combination of postpartum depression and mild or moderate OCD. At that time it was the only approved SSRI for OCD.
Posted by Bill LL on January 26, 2005, at 9:15:54
In reply to Cymbalta » Bill LL, posted by Dinah on January 25, 2005, at 9:31:49
Yes- it affects norepinephrine and serotonin.
> Hmmm. Does it affect norepinephrine? I'm pretty sure I'm going to have to call my pdoc today because I feel itchy, crawly, jumpy which is always a very very bad sign for me with AD's. I don't understand why it's doing this at 50 mg when I used to be able to tolerate 300 mg.
>
> If there is a good nonagitating alternative, I'm game to try it.
Posted by jay on January 26, 2005, at 12:41:17
In reply to Re: Tried Nortryptaline. » Kenny Koala, posted by Dinah on January 25, 2005, at 11:28:15
> Carbon copy of Effexor in my reaction. :(
>
> Are the others any different?Just a guess Dinah..but it seems all t.c. antidepressants are somewhat different from each other, despite common folklore. Amitriptyline is quite sedating, and 25-50 mg's at bedtime has helped me in the past. That is about the best one I can speak up for that I have tried. Just keep on trying, I know it's hard as hell. It *will* pay off...
Best,
Jay
Posted by jay on January 26, 2005, at 12:43:09
In reply to I hate SSRI's. I hate SSRI's., posted by Dinah on January 24, 2005, at 22:35:22
> I hate SSRI's.
>
> I hate SSRI's.
>
> I hate SSRI's.
>
> Only a few weeks on Luvox and here it is time to take it and my ears are ringing. If I forget for a few more hours (which is admittedly hard to do with the blasted ringing ears) I won't be able to sleep for the head buzzing.
>
> I'm going to quit taking the blasted stuff. I swear. It just doesn't do enough for me to justify the withdrawal. And ear ringing and head buzzing. Oh, and the increased IBS.
>
> It's a wonder drug all right.Dinah,
What other SSRI's have you tried? What kind of effects have you gotten?
Thanks,
Jay
Posted by ed_uk on January 26, 2005, at 14:39:54
In reply to Re: Luvox » ed_uk, posted by Dinah on January 25, 2005, at 16:51:02
Hi Dinah,
Since Luvox has a very short half-life, I think you might find it helpful to take 25mg Luvox twice daily. Will you try it?
Ed.
Posted by Dinah on January 27, 2005, at 19:43:47
In reply to Re: Luvox » Dinah, posted by ed_uk on January 26, 2005, at 14:39:54
If I see things getting worse, I'll start it again. But I just didn't see any benefits coming from taking it.
Maybe after being on 300 mg for nearly four years, 50 mg just isn't good for anything but ear ringing and IBS. I'm not going to try taking more though.
This is the end of the thread.
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