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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by jerrympls on January 24, 2005, at 17:53:10
Hi all-
Just thought you might like an update on my trial of oxycodone to help my TRD.
I've been on Oxycontin 10mg (along with my other meds) for about 2 weeks now. It certainly helps tremendously. I don't feel high nor do I feel a hunger for it everyday,etc. In fact, I barely notice when I take it - it's very smooth acting and "in the background."
PROS
Decreased apathy
Increased motivation
Decreased fatigue
Increase in mood/general feelings of well being
No suicidal thoughts, fantasies in 2 weeks
Decreased negative repsonse to critizism
Increase in social behaviors
Sleep seems better
Decrease in appetite (good for me)CONS
Problems with concentration & focus - thoughts muddled
Sometimes feel sleepy
Not sure it's as effective as hydrocodone
A little worried about eventually becoming tolerant - although no signs of thatAs you can see the pros outweigh the cons - but it's not a miracle treatment because I still have bad days and still have a chronic low-grade depression (that my therapist thinks can be delt with through therapy). I'd still like more motivation to get up and do stuff - maybe that's being effected by the sleepiness I get from the oxycodone? Hydrocodone give me much more of a stimulant effect. All in all I'd rather be on the Oxycodone than off. It certainly has made me the most stable mood-wise in a LONG TIME.
My doc did say we could always switch to hydrocodone - however, it would be the difference between taking one long-release tab and multiple short acting tabs/day.....I dunno..I'm still at odds about switching...
I see my doc tomorrow so we'll see what happens. Another thing: I thank the maker that I am fortunate enough to have a doctor who is willing to try opiates and only wish they'd do more studies with them for depression.
I'll keep you all updated....
Thanks
Jerry
Posted by jujube on January 24, 2005, at 21:39:05
In reply to Opiate Trials-Update 1, posted by jerrympls on January 24, 2005, at 17:53:10
Jerry,
I'm happy for you that you are noticing some improvement and positive benefits from your new med combo, and, particularly that the pros outweigh the cons. I hope that things continue to get better for you as the days go by. And, how fortunate for you to have found a pdoc who is willing to be progressive and creative in his treatment approaches. I think the fact that you are being heard and can be a more active participant in your treatment must also be a relief and must have lifted some of the burden.
Wishing you all the best. Take care of yourself.
Tamara
Posted by ed_uk on January 25, 2005, at 10:45:41
In reply to Re: Opiate Trials-Update 1 » jerrympls, posted by jujube on January 24, 2005, at 21:39:05
Hi Jerry,
It sounds like the oxycodone is really helping :-) If the sleepiness persists it might be worth trying controlled release hydromorphone (Palladone). It has a reputation for causing less drowsiness that other opioids.
Ed.
Posted by jerrympls on January 25, 2005, at 20:36:10
In reply to Re: Opiate Trials-Update 1, posted by ed_uk on January 25, 2005, at 10:45:41
> Hi Jerry,
>
> It sounds like the oxycodone is really helping :-) If the sleepiness persists it might be worth trying controlled release hydromorphone (Palladone). It has a reputation for causing less drowsiness that other opioids.
>
> Ed.Hi Ed-
I taked to my doc today and we're gonna see how things go for another week. Then if I want, we're going to try hydrocodone for a month. THEN, after trying both for a month I can either stay on the hydrocodone or go back to the Oxycontin. So I think he wants to keep it between those two opiates for now - which is fine with me.He wants to try HYCODAN which is hydrocodone and an atropine-like med combo. I guess the aptropine-like med is supposed to protect against overdose but I'm not sure if it also inhibits the "good" feelings from the opiate? I'm trying to do some research but have come up dry so far.
Jerry
Posted by ed_uk on January 26, 2005, at 14:36:13
In reply to Re: Opiate Trials-Update 1 » ed_uk, posted by jerrympls on January 25, 2005, at 20:36:10
Hi Jerry,
>He wants to try HYCODAN which is hydrocodone and an atropine-like med combo.
I think it would make more sense to use one of the combination preparations containing a very low dose of acetaminophen. Low doses of acetaminophen are very safe and rarely cause side effects. I expect you might get some anticholinergic side effects from the homatropine in the Hycodan.
Good Luck,
Ed.
This is the end of the thread.
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