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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by blanding on December 22, 2004, at 19:48:38
I've tried reboxetine, desipramine, modafinil (noradrenergics) and mirtazapine (has noradrenergic and specific serotonergic effects).
With desipramine I came close to experiencing some form of psychosis after only 5 days, then discontinued the drug. Reboxetine at 2 mg/d produced less problematic side effects, with no benefits, so I ceased taking it also.
Right now I am taking 100 mg modafinil every other day, feeling less uncomfortable 'arousal' than with reboxetine and having an inhibition to use it daily perhaps because I would then continuously experience a similar 'noradrenergic arousal' as with reboxetine.
Mirtazapine produced mixed results: On the one hand sedation, on the other hand unable to sleep well and long enough to wake up fresh. Once again I noticed the typical (for me) sensation of an uneasy noradrenergic arousal.
Posted by sabre on December 23, 2004, at 0:21:21
In reply to My Noradrenergic Experiences, posted by blanding on December 22, 2004, at 19:48:38
Hello Blanding
Why have you only used noradrenergic medications?
Is it because of your symptoms or have you already explored other options eg SSRIs?sabre
Posted by blanding on December 23, 2004, at 8:33:50
In reply to Re: My Noradrenergic Experiences, posted by sabre on December 23, 2004, at 0:21:21
Hi Sabre,
I've been on both trimipramine (atypical TCA) and sertraline (SSRI) concurrently for about 1&1/2 years now and have been adding reboxetine, mirtazapine and modafinil on the lookout for an effective augmentation (because of lack of drive/motivation to clean my apartment, groom myself etc.).
Desipramine was the only med I tried solely and that was about five years ago.
Posted by linkadge on December 23, 2004, at 10:43:12
In reply to My Noradrenergic Experiences, posted by blanding on December 23, 2004, at 8:33:50
Noradrenic meds help the depression some, but they seem to put me on another planet, one I don't recognize. I also feel very guilty on them. They seem to magnify guilt and all the things I've done wrong.
Linkadge
This is the end of the thread.
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