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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Teknohead on July 11, 2004, at 19:33:18
Hi all!
I've been on Nardil (phenelzine) now for 7 months and all of the side effects have faded away except for one - the inability to ejaculate!
What's most frustrating is that after many years of not having a girlfriend, as a result of many years of excruciating Social Phobia, I'm now in a relationship which is inevitably suffering from this damn side effect.
So, my question is, does anyone know of a med that can at least help against the inability to ejaculate whilst on Nardil?
I've already tried Viagra which had absolutely NO positive inpact on this particular problem. Although it keeps bloodflow to the penis, it hasn't helped at all with ejaculation.
And bear in mind that I live in the U.K.
Please, any ideas are welcome.
kev
Posted by Questionmark on July 12, 2004, at 1:12:53
In reply to Nardil sexual side effect, posted by Teknohead on July 11, 2004, at 19:33:18
> Hi all!
>
> I've been on Nardil (phenelzine) now for 7 months and all of the side effects have faded away except for one - the inability to ejaculate!
>
> What's most frustrating is that after many years of not having a girlfriend, as a result of many years of excruciating Social Phobia, I'm now in a relationship which is inevitably suffering from this damn side effect.
>
> So, my question is, does anyone know of a med that can at least help against the inability to ejaculate whilst on Nardil?
>
> I've already tried Viagra which had absolutely NO positive inpact on this particular problem. Although it keeps bloodflow to the penis, it hasn't helped at all with ejaculation.
>
> And bear in mind that I live in the U.K.
>
> Please, any ideas are welcome.
>
> kev
i'm sorry to hear about your difficulties. If you ever happen to find anything that helps you to have an orgasm on Nardil, please let me know because i have the same problem (Nardil, 60mg, ten months). i'll be sure to do the same if i find anything that is helpful at all. So far i've tried cyproheptadine (antihistamine and serotonin 2 antagonist- did not really help and left me horribly tired and feeling cruddy the whole next day), amantadine (a dopaminergic and NMDA antagonist- had a significantly negative effect on my mood, increased my anxiety, and did not really help all that much), and occasional low doses of methylphenidate (Ritalin) (psychostimulant- helped with libido, desire, and psychological reward, but did not seem to directly help my difficulty in obtaining an orgasm). These are options you probably want to consider, however, because they may work better for you and the side effects may not be as severe or bothersome for you. Also, Wellbutrin and Remeron, used cautiously, may offer some benefit (although for me these were also worthless-- only tried them on Paxil but still-- Remeron made me far too zombified & exhausted, and did not help; Wellbutrin made me far too anxious and nervous, and did not help).
Good luck with this. i know how freaking frusterating it can be. (What a catch 22 it is, huh?)
My next trial will be with the dopamine agonist bromocriptine. i'm trying to stay open-minded, but i don't think this will be successful, especially judging from my trial with amantadine. i'm worried, too, since my pdoc seemed to suggest that this is the last thing i would be able to try ("there is one more thing we can try...").
Ah the cost of happiness and peace.
Posted by Teknohead on July 12, 2004, at 5:43:10
In reply to Re: Nardil sexual side effect, posted by Questionmark on July 12, 2004, at 1:12:53
> > Hi all!
> >
> > I've been on Nardil (phenelzine) now for 7 months and all of the side effects have faded away except for one - the inability to ejaculate!
> >
> > What's most frustrating is that after many years of not having a girlfriend, as a result of many years of excruciating Social Phobia, I'm now in a relationship which is inevitably suffering from this damn side effect.
> >
> > So, my question is, does anyone know of a med that can at least help against the inability to ejaculate whilst on Nardil?
> >
> > I've already tried Viagra which had absolutely NO positive inpact on this particular problem. Although it keeps bloodflow to the penis, it hasn't helped at all with ejaculation.
> >
> > And bear in mind that I live in the U.K.
> >
> > Please, any ideas are welcome.
> >
> > kev
>
>
> i'm sorry to hear about your difficulties. If you ever happen to find anything that helps you to have an orgasm on Nardil, please let me know because i have the same problem (Nardil, 60mg, ten months). i'll be sure to do the same if i find anything that is helpful at all. So far i've tried cyproheptadine (antihistamine and serotonin 2 antagonist- did not really help and left me horribly tired and feeling cruddy the whole next day), amantadine (a dopaminergic and NMDA antagonist- had a significantly negative effect on my mood, increased my anxiety, and did not really help all that much), and occasional low doses of methylphenidate (Ritalin) (psychostimulant- helped with libido, desire, and psychological reward, but did not seem to directly help my difficulty in obtaining an orgasm). These are options you probably want to consider, however, because they may work better for you and the side effects may not be as severe or bothersome for you. Also, Wellbutrin and Remeron, used cautiously, may offer some benefit (although for me these were also worthless-- only tried them on Paxil but still-- Remeron made me far too zombified & exhausted, and did not help; Wellbutrin made me far too anxious and nervous, and did not help).
> Good luck with this. i know how freaking frusterating it can be. (What a catch 22 it is, huh?)
> My next trial will be with the dopamine agonist bromocriptine. i'm trying to stay open-minded, but i don't think this will be successful, especially judging from my trial with amantadine. i'm worried, too, since my pdoc seemed to suggest that this is the last thing i would be able to try ("there is one more thing we can try...").
> Ah the cost of happiness and peace.
Thanks for your input, Questionmark. A real bugger, isn't it?I'd be interested to know what the "one more thing we can try" is! Although, if you 'smoke it', then I'm affraid I gave THAT up. Wasn't good for my Social Phobia.
I'm going to try an antihistamine next. I think it will be the cyproheptadine that you've already tried. Fingers crossed!
I have read about yohimbine from the herb Yohimbe. It's not available here in the UK, but I might order some from the US, once I've checked out the compatibility with Nardil, of course. I think that herbal remedies may well be worth a try if nothing else works. Ginseng and Damiana come to mind.
Posted by jrbecker on July 12, 2004, at 10:47:45
In reply to Re: Nardil sexual side effect » Questionmark, posted by Teknohead on July 12, 2004, at 5:43:10
How high of a dose did you try with the Viagra? Supposedly, a dose at the upper range of 100-200 mg is recommended for anorgasmia.
Posted by cosis on July 12, 2004, at 21:06:37
In reply to Nardil sexual side effect, posted by Teknohead on July 11, 2004, at 19:33:18
> Hi all!
>
> I've been on Nardil (phenelzine) now for 7 months and all of the side effects have faded away except for one - the inability to ejaculate!
>
> What's most frustrating is that after many years of not having a girlfriend, as a result of many years of excruciating Social Phobia, I'm now in a relationship which is inevitably suffering from this damn side effect.
>
> So, my question is, does anyone know of a med that can at least help against the inability to ejaculate whilst on Nardil?
>
> I've already tried Viagra which had absolutely NO positive inpact on this particular problem. Although it keeps bloodflow to the penis, it hasn't helped at all with ejaculation.
>
> And bear in mind that I live in the U.K.
>
> Please, any ideas are welcome.
>
> kevHow long has the anorgasmia effected you? Mine lasted 4 months and then I could ejaculate again. Although it's not as quick as it use to be I can still do it most of the time
nick
Posted by Teknohead on July 12, 2004, at 23:57:19
In reply to Re: Nardil sexual side effect, posted by cosis on July 12, 2004, at 21:06:37
Thankyou to Questionmark, jrbecker and cosis for your input and questions. However before I go further, I must mention something about the so-called viagra I took.
It turns out they were duds! You see, I bought them from a friend, who buys them from his friend. Now he says his source gave him good ones before, but this time he agreed that they did jack shit for him too, and he doesn't take ADs. So sorry about that. At least that means it might still be worth a try! I'm ordering some off the net when I'm done here! lol
So, in answer to jrbecker, all I can say is I'll let you all know a bit more once I've tried the 'real' ones.
In answer to cosis' question, the ejaculation/orgasm problem has been there since the start, although it did get better for a while, as in your case, but it soon came back actually worse than before so that I also lose the erection within a few minutes.
By the way, I'm on 75mg of Nardil which is the dose I need to be on.
Take care all.
Posted by cosis on July 13, 2004, at 0:35:57
In reply to Re: Nardil sexual side effect, posted by Teknohead on July 12, 2004, at 23:57:19
> Thankyou to Questionmark, jrbecker and cosis for your input and questions. However before I go further, I must mention something about the so-called viagra I took.
> It turns out they were duds! You see, I bought them from a friend, who buys them from his friend. Now he says his source gave him good ones before, but this time he agreed that they did jack shit for him too, and he doesn't take ADs. So sorry about that. At least that means it might still be worth a try! I'm ordering some off the net when I'm done here! lol
> So, in answer to jrbecker, all I can say is I'll let you all know a bit more once I've tried the 'real' ones.
> In answer to cosis' question, the ejaculation/orgasm problem has been there since the start, although it did get better for a while, as in your case, but it soon came back actually worse than before so that I also lose the erection within a few minutes.
> By the way, I'm on 75mg of Nardil which is the dose I need to be on.
> Take care all.cool, i am on 75mg too, when I go up to 90mg the anorgamsia tends to come back, but i have been on nardil over 2 years now and on 75mg i am doing well
good luck
Posted by Teknohead on July 13, 2004, at 17:11:06
In reply to Re: Nardil sexual side effect, posted by cosis on July 13, 2004, at 0:35:57
Hi all.
I would like to try bethenachol but my doc wont prescribe it.
I'm not sure if I'm allowed to ask this on here so I apologise in advance. Does anyone know where I can order it off the net? It needs to be shipped to UK and bought without a prescription. I cann't find a source anywhere.
I'd be very gratefull for even the smallest hint!
Cheers.
Kev
Posted by Teknohead on July 26, 2004, at 4:20:22
In reply to Re: Nardil sexual side effect, posted by cosis on July 13, 2004, at 0:35:57
Hey everyone!
Since I last posted, I've tried two meds to try and overcome my Nardil-induced inability to ejaculate.
And did they work? Did they hell as like!
First off I ordered some rather expensive Cialis (tadalafil) 20mg tablets off the net. I tried 10mg first. Nothing except a slightly hightened sex drive. It certainly got the old boy to 'stand to attention', but any movement faster than 'really slow', and it would start to lose sensation until any possibilty of orgasm simply vanished. 20mg was no different. Bastard! What a waste of money too!
Next my doctor let me try Periactin (cyproheptadine). 4mg. Then 8mg. Absolutely nothing! Anyone know what dose it's supposed to work? My P.doc certainly doesn't! lol And I also hate that groggy feeling it gave me the next day. I ended up hitting the caffein, which I very rarely do (the withdrawals make my Social Phobia kick off again - dopamine depletion perhaps?).
Finally I tried combining 20mg Cialis with 8mg Periactin out of despiration. No added benifits at all. Disappointment is a BIG understatement.
So what now? This time I'm quite confident that Bethanechol may well be THE ONE! After some thought it seems likely that my inability to orgasm must be related to my mild urine retention. In fact, earlier on in treatment, urine retention was so bad I was wearing a catheter for nearly a month! And of course, Bethanechols main usage is for urine retention. Fingers crossed anyway!
I'll let you all know how I do.
I'll leave it there. Anyone with any more comments / sugestions, please post them.
Bye for now.
Kev.
This is the end of the thread.
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