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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by hok on June 4, 2004, at 13:11:25
did anybody have problems with word retrieval on selegiline? For some reason, I had a horrible time coming up with the names of common words.
Anyone else have this experience?
Posted by LastDyingWish on June 4, 2004, at 15:37:41
In reply to selegiline and word retrieval, posted by hok on June 4, 2004, at 13:11:25
I have no experience with this. But Iam curious as to what dose you are taking ? Selegiline is supposed to be a cognitive enhancer.
Posted by hok on June 4, 2004, at 16:16:25
In reply to Re: selegiline and word retrieval, posted by LastDyingWish on June 4, 2004, at 15:37:41
> I have no experience with this. But Iam curious as to what dose you are taking ? Selegiline is supposed to be a cognitive enhancer.
yes, it surprised me to when I experienced this effect since I know that it is commonly used for dementia. I have been experimenting with 2-10 mg daily. The higher I go on it, the more it seems to be a problem. I see the source of my lack of word retrieval as a problem with the ability to free associate and not actual memory dysfunction. it's very frustrating though!
Posted by Vanillintabaktöne on June 4, 2004, at 16:57:12
In reply to Re: selegiline and word retrieval, posted by hok on June 4, 2004, at 16:16:25
Same happened to me on Sinemet and Modopar. Although they had a definite acute effect on mood, my memory was horrible [short term]. I wonder if the dopaminergic agent have an indirect or secondary anticholinergic mechanism, and if this is what causes the memory and retrieval effects; hence cholinergic agents being used in memory problems and sometimes to balance the effects of TCA's.
For me they have a definite quieting and calming effect [the dopaminergics that is] and attention is better too. Maybe those who are experimenting with these agents should consider adding something like Aricept or Reminyl in small doses and see what happens.
I came across a very interesting article that suggests that cholinergic as well as noradrenergic and dopaminergic systems are defected in ADHD/ADD individuals and that drugs that target these systems simultaneously will have a definite impact. Quite often Methylphenidate and d-amphetamine help acutely with attentional and behavioural problems but affect somewhat negatively on short term memory and other cognitive functioning.
Be very interested to hear about anyone who is on the psychostimulants and a central cholinergic agent..........
Posted by linkadge on June 5, 2004, at 9:27:58
In reply to Re: selegiline and word retrieval » hok, posted by Vanillintabaktöne on June 4, 2004, at 16:57:12
If you look on the alternatives board, there is a dude saying that phenylalanine causes memory loss in him. Selegeling boosts PEA activity. Perhaps there is a common link.
Linkadge
This is the end of the thread.
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