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Dr. Bob is Robert Hsiung, MD,
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Posted by KennyBingo on May 24, 2004, at 20:11:57
In reply to Re: STOPPING Effexor made easy - Everyone!, posted by Vittoria on May 21, 2004, at 12:30:25
> Well, I'll give it a try ;-)
> I do not think I'll be taking another antidepressant medication to counteract Effexor's side effect: I had enough! I was already worried about it: there are so any controversial opinions! I even read some doctors calling antidrepressant a "chemical lobotomy"!
> I sure do not feel like I've been lobotomized, but I certainly wonder about the above mentioned side effects: brain shivers....? Dizzy spells? Nausea? Paranoia!
> Why? What is the scientifical explanation for it?
> It is sure intriguing....If this medication is supposed to be therapeutic and harmless, how can it have such extreme withdrawal effect?
> I do not have those answers and I think I do not want to be the guinea pig for some drug related trial!
> Thank you all, good luck and good health!
> :-)
>
>
>
>Vittoria--
I've been on Effexor at the level of 75mg-150mg for a year and a half now. I must say it has made a tremendous difference in giving me a certain emotional clarity and confidence that had always eluded me before. I do not feel lobotomized or fogged or otherwised mentally compromised in any way.
Granted, it IS powerful stuff. You'll notice that, if you miss a dose, you'll start feeling the dizzies and perhaps even the dreaded brain freezes about 30 hours after the previous dose. That's why I always carry an extra capsule in my backback.
And that's ABSOLUTELY preferable to carrying a cyanide pill in my backpack, which is what I likely would've been doing at this time were it not for a capable therapist and the good folks at Wyeth labs. Yeah, a lot of contrasting opinions. Just keep in mind that's what they are. I think much of the advice (e.g., get off Effexor and on to Prozac)needs to be recognized as a personal testimonial, rather than gospel truth. I gather you know this already. Anyway, hang in there. Best of luck to you!
ken
Posted by Tony P on May 25, 2004, at 6:07:46
In reply to Re: STOPPING Effexor made easy, posted by Spinxxie on May 21, 2004, at 13:24:08
Re other A/Ds to try, ask your pdoc about Lamictal (lamotrigine). It is only recently becoming known as an effective anti-depressant. My pdoc uses it quite a lot, and his patients report mood-stabilizing, anti-depressant AND anti-anxiety effects. I have dysthymia on top of occasional major depression (also GAD), and I am finding it mild but quite helpful at 300 mg/day for last few months. Unless you get the dreaded rash :-(, usually avoided by s-l-o-w dose escalation, it has very few side effects. Lamictal plus a small dose of Effexor might be even more effective.
I am likely also BP3 - the new suggested diagnostic category for those who have had (hypo-)manic episodes only when on regular antidepressants. Wellbutrin alone at common doses (300 mg/day) made me literally crazy, according to my family, not to speak of anxious and insomniac, so it may not be the best choice by itself for dysthymic people like us. It made my natural highs into hypo-manic episodes or anxiety attacks. I had to take substantial amounts of clonazepam (Klonopin) and zopiclone (Imovane - related to Ambien & Sonata) to deal with the side-effects.
I am still on too many benzos as well as the Lamictal, but my MD wants to go slow on reducing them. I really want to know what I feel like on just the Lamictal, but am following doctor's advice!
Tony P
-----------------------
> I am having to go off effexor because I started getting excrutiating headaches [...] The only prob is, which drug is next? I have been on luvox, wellbutrin, zoloft - sinequan - disipramine - and lithium.. all the ssris pooped out.. and.. lithium made me a zombie.. sinequan the same [...] I have had dysthemia with major depression on top of it.. and now I guess I am classified as resistant depression.. what to do? > S
Posted by ku4ns on May 25, 2004, at 14:55:35
In reply to STARTING Effexor BEFORE you stop it » Vittoria, posted by KennyBingo on May 24, 2004, at 20:11:57
My personal testimony related to stopping effexor, not as using prozac as an alternative. I used effexor for about a 1.5 years also and had very good use of the drug except for an increased heart rate. I had a terrible time trying to stop the effexor so my doc prescribed prozac to help with the side effects. The prozac removed all side effects after stopping effexor which also reduced my anxiety, which was the reason I started effexor. Effexor is a good drug, but I don't believe that all physicians that prescribe the medication know of its need for tapering as all of us do. John
> > Well, I'll give it a try ;-)
> > I do not think I'll be taking another antidepressant medication to counteract Effexor's side effect: I had enough! I was already worried about it: there are so any controversial opinions! I even read some doctors calling antidrepressant a "chemical lobotomy"!
> > I sure do not feel like I've been lobotomized, but I certainly wonder about the above mentioned side effects: brain shivers....? Dizzy spells? Nausea? Paranoia!
> > Why? What is the scientifical explanation for it?
> > It is sure intriguing....If this medication is supposed to be therapeutic and harmless, how can it have such extreme withdrawal effect?
> > I do not have those answers and I think I do not want to be the guinea pig for some drug related trial!
> > Thank you all, good luck and good health!
> > :-)
> >
> >
> >
> >
>
> Vittoria--
>
> I've been on Effexor at the level of 75mg-150mg for a year and a half now. I must say it has made a tremendous difference in giving me a certain emotional clarity and confidence that had always eluded me before. I do not feel lobotomized or fogged or otherwised mentally compromised in any way.
>
> Granted, it IS powerful stuff. You'll notice that, if you miss a dose, you'll start feeling the dizzies and perhaps even the dreaded brain freezes about 30 hours after the previous dose. That's why I always carry an extra capsule in my backback.
>
> And that's ABSOLUTELY preferable to carrying a cyanide pill in my backpack, which is what I likely would've been doing at this time were it not for a capable therapist and the good folks at Wyeth labs. Yeah, a lot of contrasting opinions. Just keep in mind that's what they are. I think much of the advice (e.g., get off Effexor and on to Prozac)needs to be recognized as a personal testimonial, rather than gospel truth. I gather you know this already. Anyway, hang in there. Best of luck to you!
>
> ken
Posted by Beta on May 25, 2004, at 19:09:28
In reply to Re: STARTING Effexor BEFORE you stop it, posted by ku4ns on May 25, 2004, at 14:55:35
I am currently prescribed 150mg Effexor XR and 0.5mg Risperdal to combat my PTSD symptoms; predominantly extreme anxiety. The Risperdal is someewhat new to me, I have been on the Effexor XR for 3 months.
I have read about, and recently began to experience the nighttime sweats daily. This is not at all fun.
Can anyone tell me if this stops, or if it's a long term side effect. The dry mouth has been bearable, but this sweating isn't.
Thanks for any insight you can provide. =)
Posted by ku4ns on May 26, 2004, at 9:31:12
In reply to Do the Effexor XR night sweats ever stop?!, posted by Beta on May 25, 2004, at 19:09:28
I experienced the night sweats a few times and that was during a dose change, after that things settled down. I was taking effexor only at the time. John
Posted by NatureGirl on May 27, 2004, at 3:14:38
In reply to Re: STOPPING Effexor made easy - alternatives » Spinxxie, posted by Tony P on May 25, 2004, at 6:07:46
I've been on Paxil about a year, and I saw my psych doc today asking to try something new. He recommended Effexor XR. I am suppose to start weaning off the Paxil tomorrow and start on the Effexor XR in about a week. What can I expect for symptoms upon starting (starter kit)? And for how long will it last? I've got some important things to do in the next 2.5 weeks...and I'm wondering if I should hold off on starting the Effexor XR until things are a little quieter in my life.
Posted by Johnpaul Q on May 27, 2004, at 8:42:22
In reply to Tell me about starting on Effexor XR, posted by NatureGirl on May 27, 2004, at 3:14:38
Hi naturegirl,
I've been on Effexor 75mg for 6 days, so am fresh with the start up symptoms.
I am having the following (from day one)
Disrupted sleep (but it wasn't great before), can't seem to sleep past four/five hours regardless of how tired i go to bed.
Dry mouth and thirsty with related needing to pee (from all the water) sometimes once an hour.
Constipation I haven't been since I started..
Sexual insensitivity, but I'm going to see that as a glass half full. I haven't lost any sex drive.
Low level tiredness through the day, probably related to the lack of sleep.
Involuntary swallowing occassionally. This is the least pleasant side affect.
Some muscle restriction in my arms
Night sweats
But to the good news, I'm not anxious anymore, the general depression appears to be lifting, tho that maybe a placebo thing.
I'm less bothered by peoples opinions than I used to be, and I'm feeling less self-critical. I changed from berating myself loudly for my clumsiness and errors in judgement, to just thinking, "Oh, Johnpaul."
Funny thing, I also don't get the energy crash after lunch that I used to.
I hope that helps.
Posted by Zarry on May 27, 2004, at 8:42:32
In reply to Tell me about starting on Effexor XR, posted by NatureGirl on May 27, 2004, at 3:14:38
well, for one thing you'll have some fun getting off Paxil - as far as starting on Effexor, it's hard to say - some ppl have no probs, some don't
Good Luck
Posted by husschick on May 27, 2004, at 12:28:32
In reply to Re: Tell me about starting on Effexor XR, posted by Zarry on May 27, 2004, at 8:42:32
For me the biggest side effects I have had is dry mouth, nausea, and loss of appetite. But for me the good out weighs the bad
good luck
Posted by PoohBear on May 27, 2004, at 13:48:01
In reply to Tell me about starting on Effexor XR, posted by NatureGirl on May 27, 2004, at 3:14:38
I've been on Effexor XR for 8 months now...eventually settling down to 150mg once a day.
As noted above, I had most of the common SE's: dry mouth, sleep disruption, constipation, sexual anorgasmia, etc. BUT, it WORKED for my depression and got rid of the continual rumminating thought processes I was putting up with.
The SE's moderate with time. I have been through several adjunct medications for sleep. Seroquel 100mg at night is what works for me. For constipation eat lots of high fiber foods and drink LOTS of water.
Suck on mints (Altoids) for dry-mouth.
Wellbutrin works for anorgasmia, but I don't need it now. Orgasms are intense and better than I've had in a long time.
The "brain zaps" and "wooshing" feeling you get when you turn your head quickly go away eventually. It's VERY important to ramp-up SLOWLY. Spend a week or two at each doseage level. Expect from the outset that while you should get SOME relief right away, the most benefit will be felt 3-6 weeks after starting treatment.
If you find that you need to get OFF, don't do it without your doctor's supervision. Go slowly and augment with Prozac.
Hope this helps. Effexor XR has been wonderful for me and for many others.
Tony
> I've been on Paxil about a year, and I saw my psych doc today asking to try something new. He recommended Effexor XR. I am suppose to start weaning off the Paxil tomorrow and start on the Effexor XR in about a week. What can I expect for symptoms upon starting (starter kit)? And for how long will it last? I've got some important things to do in the next 2.5 weeks...and I'm wondering if I should hold off on starting the Effexor XR until things are a little quieter in my life.
Posted by beatrix34 on May 27, 2004, at 19:51:26
In reply to Re: Tell me about starting on Effexor XR, posted by PoohBear on May 27, 2004, at 13:48:01
I was on 75mgs Effexor for just over a month. The SE for me were initially dry mouth, chills, racing thoughts, clouded thinking, anorgasma and insomnia. It was great in that it immediately reduced my anxiety, and I felt good for a change. All of the SE went away for me in this time except for the anorgasma coupled with total lack of sex drive, and insomnia.
I also was on Paxil years ago and went off cold turkey...not recommended. If you taper slowly you should be fine. Also, I noticed with the Effexor that I felt the most SE during the initial 37.5mg and hence stayed on that dose for another week before increasing my dose, which worked well for me. When I increased to 75mg I experienced no additional SE.
For me the lack of sleep and sex drive has proven to be a pain as I am very active and a newly-wed...yike.. so my dr suggested I taper off the Effexor and try Lexapro. I am not experiencing any issues in tapering off Effexor either maybe because I was on a low dose for a short time, thank god...
Good luck!
Posted by NatureGirl on May 27, 2004, at 23:47:44
In reply to Re: Tell me about starting on Effexor XR, posted by Johnpaul Q on May 27, 2004, at 8:42:22
> Hi naturegirl,
>
> I've been on Effexor 75mg for 6 days, so am fresh with the start up symptoms.
>
> I am having the following (from day one)
>
> Disrupted sleep (but it wasn't great before), can't seem to sleep past four/five hours regardless of how tired i go to bed.
>
> Dry mouth and thirsty with related needing to pee (from all the water) sometimes once an hour.
>
> Constipation I haven't been since I started..
>
> Sexual insensitivity, but I'm going to see that as a glass half full. I haven't lost any sex drive.
>
> Low level tiredness through the day, probably related to the lack of sleep.
>
> Involuntary swallowing occassionally. This is the least pleasant side affect.
>
> Some muscle restriction in my arms
>
> Night sweats
>
> But to the good news, I'm not anxious anymore, the general depression appears to be lifting, tho that maybe a placebo thing.
>
> I'm less bothered by peoples opinions than I used to be, and I'm feeling less self-critical. I changed from berating myself loudly for my clumsiness and errors in judgement, to just thinking, "Oh, Johnpaul."
>
> Funny thing, I also don't get the energy crash after lunch that I used to.
>
> I hope that helps.========
Hi JohnPaul...
Thanks for responding...definitely nice to get someone's recent perspective. My sleep has been horrible with Paxil for almost 6 months, so I don't know that I'll notice a difference on Effexor. Fingers crossed I don't get the sexual side effects, that's never fun :-( Most of the other symptoms sound tolerable, I've also been supplementing the Paxil with Xanax for my Anxiety attacks and it helps me a lot...so I do have that to fall back on until the Effexor kicks in - glad to hear Effexor works for your Anxiety, I'd rather take 1 drug than 2 - Paxil never helped with my anxiety. I'm also looking forward to being less critical of myself.Thanks again for your input. Keep posting and let me know how you're doing.
- NatureGirl
Posted by NatureGirl on May 27, 2004, at 23:55:26
In reply to Re: Tell me about starting on Effexor XR, posted by Zarry on May 27, 2004, at 8:42:32
> well, for one thing you'll have some fun getting off Paxil - as far as starting on Effexor, it's hard to say - some ppl have no probs, some don't
>
> Good Luck============
I've been more worried about getting off the Paxil than starting the Effexor. I've heard bad stories. I will definitely wean myself off of it slowly. Cold Turkey is about the worst thing you can do on any AD drug. About a month ago I missed taking my Paxil for 3 days and I got that real scary 'I think I'm losing my mind' feeling. I absolutely hate that. At least I understand it enough to know why it happens and that I can take the medicine and feel better soon.Thanks for the luck...can always use a little bit of that.
- NatureGirl
Posted by NatureGirl on May 28, 2004, at 0:11:27
In reply to Re: Tell me about starting on Effexor XR, posted by PoohBear on May 27, 2004, at 13:48:01
> I've been on Effexor XR for 8 months now...eventually settling down to 150mg once a day.
>
> As noted above, I had most of the common SE's: dry mouth, sleep disruption, constipation, sexual anorgasmia, etc. BUT, it WORKED for my depression and got rid of the continual rumminating thought processes I was putting up with.
>
> The SE's moderate with time. I have been through several adjunct medications for sleep. Seroquel 100mg at night is what works for me. For constipation eat lots of high fiber foods and drink LOTS of water.
>
===============
** My doc has been giving me Ambien for sleep meds, and they don't work that great. I have to take 2 to really get to sleep 'Eventually'...and I try not to take them regularly because I'd rather not get hooked on them. The lack of sleep problem seems to be an issue with Effexor, as I've been hearing. I hate to hear that because that's one of the things I've been hating and was crossing my fingers that would go away with Effexor. Why can't any of these drugs treat all the issues? Is that really too much to ask with all that man has accomplished?
===============> Suck on mints (Altoids) for dry-mouth.
**** Already hooked on Altoids...not a problem.> Wellbutrin works for anorgasmia, but I don't need it now. Orgasms are intense and better than I've had in a long time.
***** Good for you! Those of us that suffer these symptoms on a daily basis deserve something enjoyable.> The "brain zaps" and "wooshing" feeling you get when you turn your head quickly go away eventually. It's VERY important to ramp-up SLOWLY. Spend a week or two at each doseage level. Expect from the outset that while you should get SOME relief right away, the most benefit will be felt 3-6 weeks after starting treatment.
*** Really hate that waiting period...but it's to be expected.
> If you find that you need to get OFF, don't do it without your doctor's supervision. Go slowly and augment with Prozac.
>
> Hope this helps. Effexor XR has been wonderful for me and for many others.
***** So glad to hear some assurance. Thanks Tony... --- NatureGirl> Tony
Posted by johnstn on June 1, 2004, at 3:57:13
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
Has anyone found Effexor to be be more effective than Prozac for depression/anxiety? I have been on Prozac for 5 years 40mg/day and it seems to be less effective now than it used to be. What about taking Effexor as an augment to Prozac? (I don't want to take Wellbutrin.)
Posted by Johnpaul Q on June 1, 2004, at 12:39:31
In reply to Re: Tell me about starting on Effexor XR, posted by beatrix34 on May 27, 2004, at 19:51:26
Well,
11 days now. The constipation, ahem, cleared up. I get the muscle freezing (i think that was the swallowing - though maybe they are 'brain zaps?? after yawning mostly, or just when very tired. Sleep slightly improving. Night sweats still constant, as is anorgasma, which is beginning to be a pain. Dry mouth not so bad, certainly not as bad as when I was on the Atkins diet.
Still worth it tho. My friends think I'm happier and more placid, though I'm not sure placid is what I want to be!
Posted by kgirl on June 3, 2004, at 13:40:41
In reply to Re: STOPPING Effexor made easy - alternatives » Spinxxie, posted by Tony P on May 25, 2004, at 6:07:46
Hello to everyone. I'm on the final "weaning off" stage of Effexor. I am down to 37.5 every other day. Effexor was very helpful to me but now I want to try and live without it. One thing I am now finding in weaning off is that all of a sudden I am really quite angry for no apparent reason. I also have a pretty constant headache. Did anyone experience this or anything like it when they were weaning off? When you were completely off, did these symptoms go away? Any help is appreciated as I have found this site to be wonderful in my Effexor experience. Thanks.
Posted by leeeddie2 on June 4, 2004, at 0:17:49
In reply to Re: STOPPING Effexor made easy - alternatives, posted by kgirl on June 3, 2004, at 13:40:41
I am on effexor,my wife is a nurse and has told me that stopping it or suddinly stopping it can cause anger or even make you have violent outburst.as with all meds that effect brain chemistry you have to expect sideeffects even ones not noted by research everyone responds differently to differnt meds.i do feel calmer takeing it none of the others have work well as effexor but i do have feelings of sometimes my heart isnot doing right.one thing to be considered with such meds is can you cope with the sideeffects better than the way you are feeling before takeing the meds.
Posted by Joey Catch on June 8, 2004, at 20:35:03
In reply to Re: STOPPING Effexor made easy, posted by Zarry on May 21, 2004, at 10:18:36
I've been on Effexor for about five months now, and am considering getting off of it. I'm planning to study abroad in Russia in the fall, and have no idea about Effexor's availability there, and don't want to get stuck in a foreign country with no supply of medication, and be forced to go through the miserable withdrawal experience while I'm there. My current dosage is 75 mg, which is what I've been at since starting out the first two weeks at 37.5 mg. I've read here that Prozac is helpful with eliminating the withdrawal symptoms of Effexor, as are antihistamines (Benadryl, Claritin, etc.) and drugs that reduce motion sickness (Dramamine, Bonine, etc.). A few questions:
1. When switching from Effexor to Prozac, should one still taper one's dosage of Effexor, or simply quit it altogether and begin taking Prozac in its place?
2. At 75 mg of Effexor, what dosage of Prozac should I be on for it to offset the withdrawal symptoms?
3. Do these drugs (Prozac, antihistamines and motion sickness pills) effectively help avoid the "brain zaps" that comes with going off of Effexor? To be honest, this is the only side effect I really care about avoiding. Knowing how bad this SE is after missing even a single day's dose, I don't want to go through the hell of two weeks (or longer!) of brain zaps. I've gone out of town and forgotten my medicine for only a weekend, and by the end of it I was so miserable from the brain zaps, and I had light sensitivity so bad that I could hardly stand to be outdoors or even in a well-lit room. Please tell me that Prozac, Benadryl or Dramamine will do something about this.
Thanks for any assistance that you may be able to provide; I've learned a lot from reading this board and want to get off of this stuff while I can still control it, rather than wait and see what surprises the Russian medical system has in store for me regarding prescription drug availability.
- Joe
Posted by Zarry on June 9, 2004, at 9:51:12
In reply to Re: STOPPING Effexor made easy, posted by Joey Catch on June 8, 2004, at 20:35:03
Joe, all your points are valid, but as everyone has said, work with your doctor - he/she should have the answers. The biggest question you need to ask yourself, why are you on Effexor to begin with?
If you have a NEED to be on an AD, then you need to consider what to be on afterwards. Some people have been on ADs just to get them over a rough point in their life. Others HAVE to be on it to survive. I agree with you that being in a foreign country while trying to get off Effexor wouldn't be a wise thing to do.
I can't answer your questions about doseage of Prozac, whether other meds also help the SEs, etc. as I went cold turkey off Effexor and 3 wks later was on Wellbutrin, 3 wks later got hives from it and now I'm on nothing. I'm in counseling and everyone involved believes I really am not depressed. Personally I've been doing pretty good w/o any ADs. Now ask my family and they would probably disagree - you see, I actually have emotions now. They aren't used to it.
To sum things up, work with your doctor about what is best for you. Use the information you have gathered here and work with your doc. Most are open-minded and work with their patients.
Good luck and keep in touch on what you find out.
Posted by Bill LL on June 10, 2004, at 9:06:30
In reply to Re: STOPPING Effexor made easy, posted by Joey Catch on June 8, 2004, at 20:35:03
Are you using Prozac just to wean off Effexor? Or do you plan to keep taking it?
If it's just to wean off Effexor, you might try 20 mg Prozac per day for 2 weeks, then 10 mg until the second week after completely stopping Effexor.
Are you doing well on Effexor? If so, why not take enough with you to Russia to last the whole trip?
Posted by FaithT on June 12, 2004, at 8:37:16
In reply to Re: STOPPING Effexor made easy, posted by Joey Catch on June 8, 2004, at 20:35:03
Dear Joey~
I just posted above in regard to my issues stopping Effexor XR.
After I read your post, I took a Dramamine to see if this will hopefully help these "brain zaps", that I've been having for 2 days now.
I'll let you know if it really works...Thank you for your post.
Faith
Posted by Lori Ann on June 12, 2004, at 11:19:28
In reply to Re: STOPPING Effexor made easy » Joey Catch, posted by FaithT on June 12, 2004, at 8:37:16
I missed a dose of effexor (75 mgs.) this past winter and thought that I had the flu. I didn't put two and two together. Well after going to Weight Watchers last Saturday, I realized that I actually gained 30 plus pounds. I was devistated!! There was no rhyme or reason, because I really haven't been eating more than usual. Then it hit me....could this new wonder drug actually be making me fat!! I then decided to call my doctor and ask him to switch my antideppresant. Well he did...he put me on Wellbutrin and told me just to stop taking the effexor. BIG MISTAKE! I had the absolute worst withdraw symtoms known to man!! I had vertigo and brain flashes that only someone who has gone through this terrible ordeal would comprehend. So, I called my doctor crying, and he put me on prozac - 20 mg. It has been a LIFESAVER. I can now drive a car and function like a human being. Please - please if you are going through terrible withdraw symptoms, please ask your doctor for prozac. It truly works! By the way, I only lost .8 lbs this week and I followed Weight Watcher to a "t". That effexor should be banned in the United States!!
Posted by tripperjoe on June 12, 2004, at 22:33:45
In reply to Re: STOPPING Effexor made easy, posted by Lori Ann on June 12, 2004, at 11:19:28
I love effexor withdrawal. Its just like being drunk for weeks on end without having to gulp down a quart of vodka a day. I take my usual dose for a week, then two weeks off, then back to my dosing. The visuals are great, and remind me of my first year of college and LSD.. yumm. It is ironic that you cant buy a joint, but they will let you pop these bad boys.. Gotta love the capitalists eh..
Posted by oceanwolf on June 14, 2004, at 4:52:50
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
I've been taking 150mg Effexor XR for over 3 months now, haven't been back to the doctor to get a higher dose because I've been able to exist now and I've been busy getting back into summer work. Missing one day would never effect me, however when I ran out of my prescription (on a Thursday), the second day I started feeling extremely dizzy, and overall like crap! Then came the nauceousness and "unusual" BAD dreams. I unfortunately had to wait over the weekend and finally got a new scrip on a Monday and started feeling better soon after, especially the next day. No other SSRI's have worked on me, and Welbutrin only made me irritable (so the people who were closest to me said). It's nice to finally have something that is dealing with the extreme side of my depression.
Please tell me more about drinking on Effexor...I've been drinking on and off and don't seem to notice a difference. (Except that I can't drink as much as I used to without getting a headache)...
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