Psycho-Babble Medication Thread 234582

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High-dose Zoloft - interesting possibility.

Posted by Caleb462 on June 17, 2003, at 14:08:22

As we all know, Zoloft is an SSRI. However, Zoloft also happens to have *some* affinity for the dopamine transporter as well. I'm wondering why no p-docs have tried patients on trials of high-dose Zoloft, say 400 mg or so.

It could be an option for treatment resistant patients, who need a dopaminergic "kick", as well as serotonergic action.

Re: High-dose Zoloft - interesting possibility. » Caleb462

Posted by ace on June 18, 2003, at 0:17:21

In reply to High-dose Zoloft - interesting possibility., posted by Caleb462 on June 17, 2003, at 14:08:22

I know what you are saying, but, in my case, 25mg Zoloft worked as good as 200mg! It was truly a mediocre drug for me, but of course everyone is different.

Ace.

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