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Dr. Bob is Robert Hsiung, MD,
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Posted by Jack Smith on February 24, 2003, at 15:30:54
Anyone have an idea if Cymbalta has a longer half life than Effexor--I am just wondering if its withdrawl symptoms will be less severe than effexor's notoriously bad withdrawls. I am also curious if I would have withdrawls form effexor, had none on paxil and I always thought Paxil was the worst offender in this area. . . .
JACK
Posted by SLS on February 24, 2003, at 18:23:42
In reply to Cymbalta (Duloxetine): Half Life, Withdrawls, posted by Jack Smith on February 24, 2003, at 15:30:54
> Anyone have an idea if Cymbalta has a longer half life than Effexor--I am just wondering if its withdrawl symptoms will be less severe than effexor's notoriously bad withdrawls. I am also curious if I would have withdrawls form effexor, had none on paxil and I always thought Paxil was the worst offender in this area. . . .
>
> JACK
Hi Jack.The half-life for duloxetine is 10-15 hours.
Both Paxil and Effexor are comparable with respect to withdrawal syndrome. Effexor is probably a little worse.
- Scott
Posted by Jack Smith on February 24, 2003, at 19:12:48
In reply to Re: Cymbalta (Duloxetine): Half Life, Withdrawls, posted by SLS on February 24, 2003, at 18:23:42
Isn't Effexor's half life about 4 hours? Scott, I know you have tried effexor, how did you handle the withdrawl? I am in a little bit of a bind. I am dealing with ssri poopout--celexa. I am coming off of it now but added wellbutrin--up to 400 mg now. WB is okay but nothing like how celexa was in the first place. I had made up my mind about going on an MAOI--probably Parnate but my pdoc, who expressed his willingness to prescribe an MAOI, thought I should try effexor first. He said the choice was mine. I could get off celexa and WB within a week and a half or I could stick with WB and add Effexor. I am tempted to add the Effexor I just am worried that if it doesn't work, I will have a hell of a time coming off it before I can give an MAOI a trial. I have depression with atypical symptoms along with physical anxiety sypmtoms such as a constant tightness in the chest. I am confident an MAOI could put me into remission but maybe I haven't tried enough of the "new" ad's before I move on to an MAOI (I've tried paxil, celexa and WB, all with very adequate trials of over 12 weeks) (not interested in TCA's).
JACK
This is the end of the thread.
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