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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Mauro on December 7, 2001, at 18:51:06
Is there anyone able to answer to this question?
I have red a lot about GHB but I haven't understand yet if it is a medical antidepressant or a drug!
Anybody could share own experience on the use of GHB?
Tanks a lot!
Posted by paxvox on December 7, 2001, at 20:36:56
In reply to GHB: is it, finally, a simply street drug?, posted by Mauro on December 7, 2001, at 18:51:06
GHB is a street drug, or perhaps better defined as a kitchen made drug. It is not used, to my knowledge, ANYWHERE as a legitimate med. I do know that it is very dangerous, because the producers use many WEB recipes that may be very harmful and dangerous. IMHO, don't muck with it!
PAX
Posted by JGalt on December 8, 2001, at 0:03:28
In reply to GHB: is it, finally, a simply street drug?, posted by Mauro on December 7, 2001, at 18:51:06
Hehe, that's a real can of worms right there. You'll get many people on either side of the line.
As for whether or not it is a medicine, currently, there is a drug coming out called Xyrem which is used to treat nacrolepsy, and supposedly is nothing more than ghb or a close analogue. Likely it'll be another modafinil and be prescribed for a hundred other conditions that it wasn't approved for but works well for, and some pharmaceutical company will get rich selling something that was cheap as dirt to obtain good quality bulk amounts of only a coupla years ago when it was legal as a natural supplement (as it is found in the human body and animal meats, albiet in small quantities).
My experience w/ the drug in low dosages:
1. Improves mood significantly
2. Enhances motivation
3. Is stimulating but will allow you to sleep
4. Is socially disinhibiting
5. Reduced anxiety
6. No tolerance (provided you do not dose more often than once every 6 hrs)
7. Improved empathy
8. Makes any boring or repitive task able to be done without much complaint (hehe, don't tell this to the communists, next thing you know they'll be shoving ghb down all their citizens throats to get them to work for the collective w/o complaining)The negatives at low dosages (for me, 1.25-2ml's or grams):
1. Memory and cognitive ability are altered very minimally. Much less than benzodiazepines cause for me.
2. Increased time to orgasm (personally I don't care, being close to someone is very pleasurable w/o going further on this)At high dosages (for me, 2.75+ ml's or grams) these are the benefits:
1. Greater social disinhibition
2. Is very easy to go to sleep
3. In a social situation, you'll be making a lot more jokes and laughing at other jokes a very lot more
4. Some people have increased sex drive at these higher dosages while others have no such effect.
5. Euphoria in otherwise mildly pleasurable social situation.At the high dosages, for me, these are the negatives:
1. Memory and cognitive deficits are equal to a low dose of ativan for me (.5-.75mg) or clonazepam (1mg)
2. If used to go to sleep with at these higher dosages, I seem to have reduced memory the next day, not too great, but its there, also some respiratory depression the next day.
3. Driving is dangerous idea
4. There is the potential to pass out for me at dosages about 3.5ml's or grams into a deep sleep for a few hrs (wake up feeling fine, but almost completely unrousable while in this sleep)
5. Using GHB chronically (several times a day at dosages probably above 2.5ml's or grams a time for weeks on end) has the potential to produce absence seizures in prone people due to ghb's agonist effect on gaba-b receptors. Please note that taking an anticonvulsant such as clonazepam would only worsen this.So that's my experience. Anymore I stick with the low dosages all the time. The added benefits of the higher doses are simply not worth the side effects and risks for me. Granted it is fun at higher dosages for social events such as parties (do not drink alcohol though on ghb), but even then I keep it to a mid range dose, from 2-2.75 ml's or grams. I also use about 2.25ml or g's dose after particularly hard workouts. The muscle relaxant and mild analgesic effect of the mid range doses are quite nice, and the side effects aren't bad at midrange doses, and usually I like to relax after a workout anyway.
JGalt
Disclaimer: Any mention of ghb by JGalt refers not to ghb but to a similar substance which is legal in his state and country.
Posted by Elizabeth on December 8, 2001, at 0:25:06
In reply to GHB: is it, finally, a simply street drug?, posted by Mauro on December 7, 2001, at 18:51:06
> Is there anyone able to answer to this question?
> I have red a lot about GHB but I haven't understand yet if it is a medical antidepressant or a drug!At the moment it's illegal in the U.S., but it's being studied here (and is already used in some places) for narcolepsy.
-elizabeth
Posted by Anna Laura on December 8, 2001, at 1:32:54
In reply to Re: GHB: is it, finally, a simply street drug? » Mauro, posted by paxvox on December 7, 2001, at 20:36:56
> GHB is a street drug, or perhaps better defined as a kitchen made drug. It is not used, to my knowledge, ANYWHERE as a legitimate med. I do know that it is very dangerous, because the producers use many WEB recipes that may be very harmful and dangerous. IMHO, don't muck with it!
>
> PAXI know for sure that ghb has been used in Italy by the psychopharmacologist and researcher Gianluigi Gessa of the University of Cagliari.
They're using it for the treatment of alcholism and other addictions with success. I don't know any study or scientific evidence about its employment for the treatment of depression.
Professor Gessa is known worldwide because of his research and findings on dopamine.
I tried to get in touch with professor Gessa a month ago after i found out they're using new dopaminergic drugs for the treatment of depression : i've been talking with a woman of the university clinic staff who told me that you have to be a resident in order to follow their program. (Too bad!).
Posted by paxvox on December 8, 2001, at 21:06:41
In reply to Re: GHB: is it, finally, a simply street drug? No, posted by Anna Laura on December 8, 2001, at 1:32:54
I didn't say the actual chemical mixture of GHB itself was dangerous (though I personally think it to be) as much as I was trying to suggest that as an illegal drug in the US, the street made version IS dangerous, because one never knows exactly what one is getting. This would be similar to buying heroin or cocaine off the steet, you have no idea what it has been cut with, or its purity. Here is where I see the danger with any street drug, and the number of drug-related deaths world wide would seem to support this. There MAY some day be a legitimate use for GHB WHEN given by a doctor. In any other circumstance, you are playing with fire.
PAX
Posted by JGalt on December 9, 2001, at 10:12:18
In reply to Re: GHB: is it, finally, a simply street drug? No » Anna Laura, posted by paxvox on December 8, 2001, at 21:06:41
PAX,
I agree with you that if you buy it off the street, it is potentially dangerous. Some people have been known to use highly substandard chemicals in the process or out of date synthesis. A simple synthesis from GBL-GHB using NaCl isn't at all difficult, but more complicated synthesis not using GBL as a precursor are certainly more dangerous...not only that, on the street if you ask for GHB, you are probably just as likely to receive ropheynol, another supposed date-rape drug with very powerful effects.
The point we, or at least I, am making here, is that not all of us buy it off the street, and some of us remember what it was like back when it was legal and large scale chemical manufacturer's were turning out tons and tons of 99.99% pure product a day. When it was legal, we didn't have the problem of impurities. No one in their right mind would bother with a complicated synthesis if they could buy guaranteed pure product just as cheap.
I disagree that it should be administered by doctor's care. Legalize it, along with all drugs. Eliminates drug caused violence, funding of underground organizations such as Al-Quida, puts drug czars out of power, makes sure people receive pure product and needles (thus reducing spread of HIV), and most of all, gives us the fundamental right of being human, that is, to live as we wish so long as it harms no one else.
JGalt
This is the end of the thread.
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