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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by AVR on August 9, 2001, at 4:41:41
Hi, I just went to Paxil-side-effects.com and it came to me that I have had almost every one of these side effects listed in the period of time that I took Paxil. Some went and came back and some stayed.
For the last few months maybe the last 4 months I have had this weird skin discolouration on my face. My cheekbones are white and the resy of my face is slightly red. It's weird looking. I am off Paxil now and experiencing some withdrawl symptoms. I am waiting to see if this rash type skin defect will go away since I am off the Paxil. Is it dangerous to experience a rash on Paxil? I heard that this could be a sign of a serious medical condition.
Posted by SalArmy4me on August 9, 2001, at 8:58:25
In reply to skin discolouration on paxil??, posted by AVR on August 9, 2001, at 4:41:41
Paxil has a rash as an uncommon side-effect; nowhere did I find that Paxil was discontinued because of a rash in clinical trials...
MARGOLESE, HOWARD C. M.D. Cutaneous Vasculitis Induced by Paroxetine. American Journal of Psychiatry. 158(3):497, March 2001.
"...Other dermatologic adverse effects, including pruritus, rash (mainly urticarial), and ecchymosis, among others, have been reported with paroxetine (4). However, to our knowledge, this is the first report of cutaneous vasculitis induced by paroxetine. The reemergence of the problem during another trial with the drug strongly supports the association between the two. Paroxetine's high-affinity binding to human platelet membranes (5) and serotonin's ability to induce and augment platelet aggregation (6) may explain this reaction. Physicians should be alert to this potential serious complication with antidepressant medications, including paroxetine..."
Mir, Shameem. Taylor, David. The adverse effects of antidepressants. Current Opinion in Psychiatry. 10(2):88-94, March 1997:
"Rare adverse effects such as rash (especially with fluoxetine) and hair loss [23,24] have been reported..."
This is the end of the thread.
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