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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by Joe Schmoe on August 7, 2001, at 18:30:33
I am wondering, instead of Celexa + Wellbutrin, has anyone ever tried Wellbutrin + Serzone? If so, what condition were you treating, how did you like the combo, and what other drugs were you on?
Posted by SalArmy4me on August 7, 2001, at 18:36:51
In reply to Wellbutrin + Serzone? Anyone ever tried it?, posted by Joe Schmoe on August 7, 2001, at 18:30:33
The result of Nefazodone + Buproprion is:
1) Serotonin 2A Receptor Blockade
2) Weak Serotonin Reuptake Inhibition
3) Dopamine reuptake inhibition
4) norepinephrine reuptake inhibition.Sounds like a nice combo that avoids the side-effects of strong serotonin reuptake inhibition.
> I am wondering, instead of Celexa + Wellbutrin, has anyone ever tried Wellbutrin + Serzone? If so, what condition were you treating, how did you like the combo, and what other drugs were you on?
Posted by Cindylou on August 7, 2001, at 21:34:24
In reply to Wellbutrin + Serzone? Anyone ever tried it?, posted by Joe Schmoe on August 7, 2001, at 18:30:33
Hi,
I haven't tried that combo (I'm on Prozac + Wellbutrin), but my pdoc suggested it as an option if the Prozac doesn't work. She said Serzone does NOT have the sexual side effects that the SSRIs have, and that it is a bit sedating, which could help with your anxiety.I think it would be a good option.
Take care,
-cindy> I am wondering, instead of Celexa + Wellbutrin, has anyone ever tried Wellbutrin + Serzone? If so, what condition were you treating, how did you like the combo, and what other drugs were you on?
Posted by Emme on August 8, 2001, at 7:22:06
In reply to Wellbutrin + Serzone? Anyone ever tried it?, posted by Joe Schmoe on August 7, 2001, at 18:30:33
Hi. At one point I had been on Serzone and it wasn't working by itself for the depression. We added 150 mg Wellbutrin and within about a week I had a dramatic improvement. I was really amazed - it was like night and day. I had energy but wasn't overstimulated or sedated. I wasn't on anything but those two drugs. Definitely worth a try.
Emme
> I am wondering, instead of Celexa + Wellbutrin, has anyone ever tried Wellbutrin + Serzone? If so, what condition were you treating, how did you like the combo, and what other drugs were you on?
Posted by akrake on August 8, 2001, at 8:35:15
In reply to Re: Wellbutrin + Serzone? Anyone ever tried it? » Joe Schmoe, posted by Cindylou on August 7, 2001, at 21:34:24
>
> I haven't tried that combo (I'm on Prozac + Wellbutrin), but my pdoc suggested it as an option if the Prozac doesn't work. >
>
>
> How long have you been doing the prozac/wellbutrin combo? which did you take first? did the prozac take the edge off wellbutrin? i'm concerned about sexual side effects also....can i pry?amie
>
Posted by terra miller on August 8, 2001, at 11:44:04
In reply to Wellbutrin + Serzone? Anyone ever tried it?, posted by Joe Schmoe on August 7, 2001, at 18:30:33
> I am wondering, instead of Celexa + Wellbutrin, has anyone ever tried Wellbutrin + Serzone? If so, what condition were you treating, how did you like the combo, and what other drugs were you on?
i loved this combination. i couldn't keep it up, though, because it gave me too much serotonin effects. but i loved serzone by itself. and i love wellbutrin by itself. i just got maxed out on the serotonin combining both, but i really think that's just me and not the norm.
let's see. i tried the combo for sleep and for calming. i did well previously on serzone taking it all at bedtime (350mg) once a day. it was great for sleep. i also thought the serzone had very few sideeffects, similar to wellbutrin but not agitating like the wellbutrin. serzone also didn't leave me feeling numbed out/unfeeling/doped up like SSRI's did while still providing anti-depressant effects. there were no weight issues, or sexual fxning issues with the serzone.
i think it's a great mix. just keep an eye on any side-effects which seem unique to each person. can go further with that if you want more specifics.
-terra
Posted by Cindylou on August 8, 2001, at 12:46:53
In reply to Re: Wellbutrin + prozac » Cindylou, posted by akrake on August 8, 2001, at 8:35:15
Hi Amie,
Well, I've been on and off antidepressants for many years -- I stopped completely when I got pregnant, and am having trouble getting back on meds without bad side effects. It's been a year and a half that I've been going from one thing to the next.Before pregnancy, I was on Zoloft and wellbutrin for about 2 years. I started with the Zoloft, then added Wellbutrin to help offset the fatigue I felt with the Zoloft. It seemed to help a bit, but I was still tired.
This time, I just started Prozac a couple of months ago (after a long, yucky bout with Effexor). I automatically took the Wellbutrin with the Prozac because of the fact that SSRIs make me tired.
Anyway, it doesn't really help take the edge off of the Wellbutrin -- for some reason, this time around, the Prozac is a bit more stimulating for me. So I had to reduce the Wellbutrin I was taking.
As far as sexual side effects, I'm a bad person to ask. Embarrassingly enough, my husband and I haven't had sex since our baby was born! Neither one of us has had the energy or desire, I guess. I'm not sure if it's the medication taking away my desire or not ... I'm sure it has affected me some. But it's not really a concern right now, since that part of our marriage is non-existent at this point. We tried sex therapy, but never followed through on our "homework" because we were too tired at the end of the day! At least it's mutual.
So, long story short, I guess I'm not much help to you ... the Prozac + Wellbutrin combo seems to be helping with my fatigue and depression, which helps me be a better mom to my baby, so that's a good thing right now.
Are you on Wellbutrin alone right now, and considering adding Prozac? I know that Serzone and Remeron are not supposed have sexual side effects; have you tried those?
take care,
-cindy
> > How long have you been doing the prozac/wellbutrin combo? which did you take first? did the prozac take the edge off wellbutrin? i'm concerned about sexual side effects also....can i pry?
>
> amie
> >
Posted by Joe Schmoe on August 8, 2001, at 12:47:52
In reply to Re: Wellbutrin + Serzone? Anyone ever tried it? » Joe Schmoe, posted by terra miller on August 8, 2001, at 11:44:04
> i loved this combination. i couldn't keep it up, though, because it gave me too much serotonin effects.
I don't understand what you mean by "serotonin effects." Like what? As I understand it, wellbutrin does not affect serotonin, only dopamine.
> i think it's a great mix. just keep an eye on any side-effects which seem unique to each person. can go further with that if you want more specifics.
Specifics would be welcomed. Thanks.
Posted by akrake on August 8, 2001, at 13:45:34
In reply to Re: Wellbutrin + prozac, posted by Cindylou on August 8, 2001, at 12:46:53
> Hi cindy.
>
> Are you on Wellbutrin alone right now, and considering adding Prozac? I know that Serzone and Remeron are not supposed have sexual side effects; have you tried those?
>
i've only tried prozac...got off after a month because if the side effects....sexual...termors...high blood pressure. but it WORKED for my pmdd.....so then i tried wellbutrin but it hasn't worked so far.i may after to discuss other alternatives with my doc. thanks for the info.
amie
>
>
>
> > > How long have you been doing the prozac/wellbutrin combo? which did you take first? did the prozac take the edge off wellbutrin? i'm concerned about sexual side effects also....can i pry?
> >
> > amie
> > >
Posted by terra miller on August 8, 2001, at 20:35:01
In reply to Re: Wellbutrin + Serzone? Anyone ever tried it?, posted by Joe Schmoe on August 8, 2001, at 12:47:52
ummm.... i think it goes like this but i'm starting to get confused. :-) i think wellbutrin weakly effects serotonin, dopamine and norepinephrine. somebody go ahead and correct me if i'm wrong, but i think that's it.
for me, i just can't take too many drugs that deal with serotonin. i can always tell, because i get the same side-effect... can't pee. (sorry for being honest *she blushes*) obviously, it's a lousy side-effect. apparently any med that lists "painful erections in males" as a sideeffect, causes this can't pee sideeffect in me. (i've got a small list of meds now that i can't take.)
when i was only on serzone, i just couldn't get my dose up high enough without my body swelling up. also with serzone you can get these flashes of light/trails of light in your vision, but i found that very tolerable and not too bothersome. but that was when i was just on the serzone. and i was able to stay on it for 3-4 months before i had that swelling that was too painful to continue taking it; that really was too bad because i really loved it. i really like wellbutrin, too... but the serzone was less activating/agitating as the wellbutrin and that was the perfect balance for me. for me, serzone was like a perfect combination of an activating/get you moving med and a calming med. blablabla.... so when i tried to add just 50mg of the serzone to my current wellbutrin dose, i swelled up again and the bathroom thing... even at only 50mg (remember i had previously taken 350mgserzone.) so FOR ME, i seem to be at the perfect level of serotonin effecting meds... even the weakest of them. so i just take the wellbutrin. -terra
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