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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by mikel on February 6, 2001, at 15:09:36
Been on Serzone for almost 6 weeks (1wk 100mg,1wk 200,
3wk 300, now in 6th week at 400) for anxiety and depression.
Had success with prozac and celexa, but couldn't tolerate
side effects. I am very hopeful in that I have almost
no side effects, other than I feel like a zombie for 24- 48hrs
after upping the dose each time, but that goes away. I
felt like I had partial response on 300, but my psychiatrist said
he wants me up to 500-600 range as quickly as I can go up.
He said that when serzone first came out the theraputic
range was 300-600, but now he says the 500-600 range is \
really when the antidepressant effects kick in. My question
is has anyone had real success at the 300-400 range? The
2001 Physicians Desk Reference still lists 300-600, has
anyone else been told the 500-600 is the real target range?
I haven't heard of this change except from my doc. Since
I hardly have any side effects, I don't really have a
problem with going up, but if I also don't want to blow
past 400mg too fast if there is a chance it will work.
Posted by SalArmy4me on February 6, 2001, at 17:24:35
In reply to serzone dosage, posted by mikel on February 6, 2001, at 15:09:36
I suppose that 300-400 mg would work for you if you had mild or seasonal depression. Otherwise, you must take 600 mg.
> Been on Serzone for almost 6 weeks (1wk 100mg,1wk 200,
> 3wk 300, now in 6th week at 400) for anxiety and depression.
> Had success with prozac and celexa, but couldn't tolerate
> side effects. I am very hopeful in that I have almost
> no side effects, other than I feel like a zombie for 24- 48hrs
> after upping the dose each time, but that goes away. I
> felt like I had partial response on 300, but my psychiatrist said
> he wants me up to 500-600 range as quickly as I can go up.
> He said that when serzone first came out the theraputic
> range was 300-600, but now he says the 500-600 range is \
> really when the antidepressant effects kick in. My question
> is has anyone had real success at the 300-400 range? The
> 2001 Physicians Desk Reference still lists 300-600, has
> anyone else been told the 500-600 is the real target range?
> I haven't heard of this change except from my doc. Since
> I hardly have any side effects, I don't really have a
> problem with going up, but if I also don't want to blow
> past 400mg too fast if there is a chance it will work.
Posted by MarkinBoston on February 6, 2001, at 17:27:41
In reply to serzone dosage, posted by mikel on February 6, 2001, at 15:09:36
My pdoc also suggests the higher dosages. She has found as have others that Serzone only starts to work for most people at the higher levels. I couldn't get above 100mg. or I was a zombie until the afternoon. Amphetemines didn't help at all.
> felt like I had partial response on 300, but my psychiatrist said
> he wants me up to 500-600 range as quickly as I can go up.
> He said that when serzone first came out the theraputic
> range was 300-600, but now he says the 500-600 range is \
> really when the antidepressant effects kick in.
Posted by JennyR on February 9, 2001, at 19:24:12
In reply to Re: serzone dosage, posted by MarkinBoston on February 6, 2001, at 17:27:41
300 was great for me for about 6 months. Then I started going downhill. It was "pooping out" I was told. He upped it to 400 mg. Good for another 6 months or so. Then upped to 600 mg (the max). Great until about October when I quickly spiraled down to a very bad dark place. Then I was switched to Wellbutrin. So far, so good. My answer on Serzone - the lower doses work for a while but then poop out. But so did the max dose.
This is the end of the thread.
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