Shown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Huggave on February 4, 2001, at 12:24:24
Anybody with experience from the combination of Effexor and Remeron? According to professor Stephen M. Stahl University of California and author of several psychopharmacology books, this combo is called "California Rocket Fuel" and "has a great degree of theoretical synergy". Would be very interesting to know more about this.
Thank you!
Posted by SalArmy4me on February 4, 2001, at 12:27:04
In reply to Rocketfuel=Effexor+Remeron?, posted by Huggave on February 4, 2001, at 12:24:24
I'm on that combo. Both medicines work on the same chemicals.
Posted by allisonm on February 4, 2001, at 14:22:37
In reply to Rocketfuel=Effexor+Remeron?, posted by Huggave on February 4, 2001, at 12:24:24
There should be information in Dr. Bob's tips section. Also, if you do an advance search of the archive, typing in Effexor Remeron and checking "every term," You'll find there are 490 posts on the subject since this board began.
Good luck.
Posted by allisonm on February 4, 2001, at 14:32:01
In reply to Re: Rocketfuel=Effexor+Remeron?, posted by allisonm on February 4, 2001, at 14:22:37
When I mentioned the Dr. Bob's tips section, I meant the Psychopharmacology tips section. If you do a search of Effexor and Remeron, you will find these two posts:
Date: Sun, 27 Sep 1998 23:33:51 -0500
From: Larry Ereshefsky < ereshefsky@uthscsa.edu >
Subject: Mixing mirtazapine and venlafaxineStephen Stahl, whom I regard as the guru of the
psychopharmacology of depression, advocates such combinations as
Remeron (mirtazapine) and Effexor (venlafaxine) for difficult to treat
depressions and made no mention of any particular risk of serotonin
syndrome during a recent workshop I attended.--Jim Glover, M.D.
The combination of mirtazapine and venlafaxine is very powerful. I view it as "big
gun" therapy, almost equal to ECT. There is a risk of serotonin syndrome, as there is
with many augmentation strategies which affect the same system at several levels. It
all comes down to benefit vs. risk.Date: Thu, 1 Oct 1998 18:24:46 -0500
From: Larry Ereshefsky < ereshefsky@uthscsa.edu >
Subject: Mixing mirtazapine and venlafaxineAnecdotally, this combination is being used with good success. Granted, it's not
controlled for time on drug, etc, but treatment resistant patients are not likely to
undergo spontaneous remission or placebo response.Folks like Norm Sussman, Alan Schatzberg, and others I have served on program
panels with suggest they have had good success in selected patients.Whether the combination works better than either alone is not answerable with data.
However, the neurochemical effects of these drugs are non-duplicative, and the end
result should be greater outflow of NE and 5HT.---------
Also, if you go the Psycho-Babble tips page, there is a folder on Remeron. Within that folder is a folder on Remeron with other drugs and one within tthat on Effexor. There you will find two threads on the subject from the archives:
Posted by JohnL on February 4, 2001, at 16:07:48
In reply to Rocketfuel=Effexor+Remeron?, posted by Huggave on February 4, 2001, at 12:24:24
> Anybody with experience from the combination of Effexor and Remeron? According to professor Stephen M. Stahl University of California and author of several psychopharmacology books, this combo is called "California Rocket Fuel" and "has a great degree of theoretical synergy". Would be very interesting to know more about this.
> Thank you!St James is a longtime regular participant here and he takes Effexor+Remeron.
In Dr Bob's Tips this combination is referred to as 'big guns'. Both drugs work mostly on serotonin and norepinephrine, and to a lesser extent dopamine, except from different mechanisms. The drugs work from different angles. One symbolically opens up the spigot, while the other plugs the drain.
I've tried this combo myself however and didn't like it. It made my ears ring very loud and made me very sluggish.
John
Posted by Huggave on February 5, 2001, at 12:55:06
In reply to Re: Rocketfuel=Effexor+Remeron?, posted by JohnL on February 4, 2001, at 16:07:48
Thank you SalArmy4me,allisonm and JohnL for your response! It seems like this is one of the most powerful ways to treat depression pharmacologically, but as said before, we are all individual and what works for one person may not work for another.
Regards,
Huggave
Posted by vince on February 6, 2001, at 0:17:47
In reply to Rocketfuel=Effexor+Remeron?, posted by Huggave on February 4, 2001, at 12:24:24
> Anybody with experience from the combination of Effexor and Remeron? According to professor Stephen M. Stahl University of California and author of several psychopharmacology books, this combo is called "California Rocket Fuel" and "has a great degree of theoretical synergy". Would be very interesting to know more about this.
> Thank you!
I have some leftovers from earlier separate trials of effexor and Remeron. Several weeks ago I was just sitting around in immense psychological pain pondering what I should do with my self next when I happened across several of the archived posts on Remeron plus effexor. I hated Remeron because it made me drowsier than any medication that I have ever been on, not just anti-depressants, but anything that I can ever remember being on. Nothing has made me sleep like Remeron. I was on it for a little over a month. The side effects showed no promise of ever letting up in the least so I gave up and just left the half-full prescription in the medicine cabinet. But at this time I was desperate so I decided to experiment with Rem+Eff. I took 30 mg of Remeron 2 hrs before bedtime and 150 mg of effexor when I awoke in the morning. I awoke intermittently for the next three days just enough to move from one piece of furniture to the next. For the next three days I fell asleep at least once on every piece of furniture in the house - kitchen appliances count. If I ever decide to commit suicide but don't have the courage to go all the way I think I will compromise with Remeron and effexor. I can sleep off the next 30 years of my life - suicide by somnolence.Vince
Posted by Bill L on February 6, 2001, at 7:14:05
In reply to Re: Rocketfuel=Effexor+Remeron? » Huggave, posted by vince on February 6, 2001, at 0:17:47
Vince - Remeron is strange in that it causes less drowsiness at higher doses. So if you take more than 30 mg per day, you should expect less tiredness. This is a well known effect with most people who take Remeron. Please discuss this with your doctor to see what he thinks.
> > Anybody with experience from the combination of Effexor and Remeron? According to professor Stephen M. Stahl University of California and author of several psychopharmacology books, this combo is called "California Rocket Fuel" and "has a great degree of theoretical synergy". Would be very interesting to know more about this.
> > Thank you!
>
>
>
>
> I have some leftovers from earlier separate trials of effexor and Remeron. Several weeks ago I was just sitting around in immense psychological pain pondering what I should do with my self next when I happened across several of the archived posts on Remeron plus effexor. I hated Remeron because it made me drowsier than any medication that I have ever been on, not just anti-depressants, but anything that I can ever remember being on. Nothing has made me sleep like Remeron. I was on it for a little over a month. The side effects showed no promise of ever letting up in the least so I gave up and just left the half-full prescription in the medicine cabinet. But at this time I was desperate so I decided to experiment with Rem+Eff. I took 30 mg of Remeron 2 hrs before bedtime and 150 mg of effexor when I awoke in the morning. I awoke intermittently for the next three days just enough to move from one piece of furniture to the next. For the next three days I fell asleep at least once on every piece of furniture in the house - kitchen appliances count. If I ever decide to commit suicide but don't have the courage to go all the way I think I will compromise with Remeron and effexor. I can sleep off the next 30 years of my life - suicide by somnolence.
>
> Vince
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