Posted by allisonm on February 4, 2001, at 14:32:01
In reply to Re: Rocketfuel=Effexor+Remeron?, posted by allisonm on February 4, 2001, at 14:22:37
When I mentioned the Dr. Bob's tips section, I meant the Psychopharmacology tips section. If you do a search of Effexor and Remeron, you will find these two posts:
Date: Sun, 27 Sep 1998 23:33:51 -0500
From: Larry Ereshefsky < ereshefsky@uthscsa.edu >
Subject: Mixing mirtazapine and venlafaxineStephen Stahl, whom I regard as the guru of the
psychopharmacology of depression, advocates such combinations as
Remeron (mirtazapine) and Effexor (venlafaxine) for difficult to treat
depressions and made no mention of any particular risk of serotonin
syndrome during a recent workshop I attended.--Jim Glover, M.D.
The combination of mirtazapine and venlafaxine is very powerful. I view it as "big
gun" therapy, almost equal to ECT. There is a risk of serotonin syndrome, as there is
with many augmentation strategies which affect the same system at several levels. It
all comes down to benefit vs. risk.Date: Thu, 1 Oct 1998 18:24:46 -0500
From: Larry Ereshefsky < ereshefsky@uthscsa.edu >
Subject: Mixing mirtazapine and venlafaxineAnecdotally, this combination is being used with good success. Granted, it's not
controlled for time on drug, etc, but treatment resistant patients are not likely to
undergo spontaneous remission or placebo response.Folks like Norm Sussman, Alan Schatzberg, and others I have served on program
panels with suggest they have had good success in selected patients.Whether the combination works better than either alone is not answerable with data.
However, the neurochemical effects of these drugs are non-duplicative, and the end
result should be greater outflow of NE and 5HT.---------
Also, if you go the Psycho-Babble tips page, there is a folder on Remeron. Within that folder is a folder on Remeron with other drugs and one within tthat on Effexor. There you will find two threads on the subject from the archives:
poster:allisonm
thread:53297
URL: http://www.dr-bob.org/babble/20010131/msgs/53303.html