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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by HenryO on January 3, 2001, at 0:56:28
Reboxitine / Edronax I ordered it on-line! Its on the way! Who has experience with it? Why?(I mean whats your history) how? doses? Side effects? personal experience? I am hoping to combat wicked periods of SSRI poop-out. I am ready at times for ECT.
Posted by mr. man on January 3, 2001, at 11:58:12
In reply to Reboxitine / Edronax, posted by HenryO on January 3, 2001, at 0:56:28
> Reboxitine / Edronax I ordered it on-line! Its on the way! Who has experience with it? Why?(I mean whats your history) how? doses? Side effects? personal experience? I am hoping to combat wicked periods of SSRI poop-out. I am ready at times for ECT.I ordered it online too a while ago, after trying it for about 10 days I put the reboxetine in the garbage can, I wanted to try it because it sounded good from what I read, it was a SNRI instead of a SSRI, I had already tried a SSRI with no luck, when taking reboxetine my dose was 2mg, the effects of the drug were very strong, it feels like a strange stimulant, I believe it constricted my blood vessels because my eyes became very white which is not normal for me and I was very cold all the time, also my penis shriveled up and it was a little more difficult to urinate, I found it very hard to get to sleep and when I did sleep I was like awake sleeping if you can imagine that. The drug didnt help with depression or motivation, although I was motivated to just stand up sometimes when sitting down because if I sit down to long I started to feel anxious and feel my heart pumping, its hard to explain. Anyway I know you have high hopes for this drugs, it could end up working great for you, I had a bad experience with it but who knows what it will do for you. If you asked me what to try next if this drug doesnt work out then I would answer--amisulpride, possibly taking adrafinil with it. Actually I would suggest anyone try amisulpride.
Posted by Neal on January 4, 2001, at 0:26:15
In reply to Re: Reboxitine / Edronax, posted by mr. man on January 3, 2001, at 11:58:12
If your symptoms are apathy and lack of energy, Rebox may possibly help. If you have a lot of anxiety, leave it alone. It has some side-effects, some of which dissipate over time.
Posted by cole on January 5, 2001, at 14:04:49
In reply to Re: Reboxitine / Edronax, posted by Neal on January 4, 2001, at 0:26:15
I ditched my remeron to give rebox a shot, and was driven into a deep depression faster than I usually reach on my own. I honestly feel like it made me depressed. In perspective, I also react abnormally to the SSRI's. They lift the depression a little but keep me at a strange level of paranoia, anxiety and agitation. As a female on rebox I didn't have any sexual side effects or urinary problems. I've seen a number of men posting that they did have noticeable urological problems at least in the beginning. Give it a shot but do pay attention to your moods-- perhaps get a friend or family member to keep an eye out for signs you are slipping into a deeper depression.
cole
Posted by SLS on January 5, 2001, at 15:02:38
In reply to Re: Reboxitine / Edronax, posted by cole on January 5, 2001, at 14:04:49
> I ditched my remeron to give rebox a shot, and was driven into a deep depression faster than I usually reach on my own. I honestly feel like it made me depressed.
Me too. It made me suicidal. I am not generally suicidal, regardless of the depth of my depression. In addition to worsening my depression, reboxetine produced in me significant anxiety. Anxiety and aggression are perhaps the two most important features associated with successful suicides.
I know I keep saying this from time to time, but there is a biology of suicidality - a neurochemical substrate that alters one's mental state to not only experience thoughts that are catastrophic in nature, but to actually *feel* suicidal, regardless of cognitive content. Drugs can make perfectly healthy people become suicidal who never had a suicidal thought in their whole life.
IMHO.
Cole, your system probably would react kindly to the addition of predominately dopaminergic (DA) drugs, including those which block 5-HT2a receptors. Wellbutrin does not fit into any of these categories.
5-HT2a = Remeron, Serzone, and Desyrel.DA = Amisulpride, Mirapex, Parlodel
DA + 5-HT2a = Risperdal, Zyprexa, Seroquel, and Zeldox (hopefully to be soon released for market)
Dexedrine, Adderal, Ritalin, and Cylert might be partially effective augmentors.
Try the lithium first. :-)
- Scott
Posted by JohnL on January 5, 2001, at 16:26:58
In reply to Reboxitine / Edronax, posted by HenryO on January 3, 2001, at 0:56:28
> Reboxitine / Edronax I ordered it on-line! Its on the way! Who has experience with it? Why?(I mean whats your history) how? doses? Side effects? personal experience? I am hoping to combat wicked periods of SSRI poop-out. I am ready at times for ECT.
You might want to start with real low doses. If it's not the right drug for you, you will know very quickly. Won't be any doubt.
If it doesn't work out--though I have my fingers crossed that it will--definitely order Adrafinil and Amisulpride before doing anything else. Let me know if you need email addresses to order them.
John
Posted by cole on January 6, 2001, at 14:46:55
In reply to Re: Reboxitine / Edronax » cole, posted by SLS on January 5, 2001, at 15:02:38
> Me too. It made me suicidal. I am not generally suicidal, regardless of the depth of my depression. In addition to worsening my depression, reboxetine produced in me significant anxiety. Anxiety and aggression are perhaps the two most important features associated with successful suicides.
Aggression and anxiety have always been components of my depression, and my depression has periods of total suicidal ideation. Luckily I haven't attempted for a number of years. I was reaching that level of anxiety and aggression on tuesday morning. I completely agree that those are good indicators-- once I am getting really bad I start off aggressive, and anxious-- driving recklessly, disorganized thoughts etc and quickly slow down into a suicidal depression. I really feel better now, I only wish I could improve my concentration quicker. That seems to build more slowly a few weeks while the anxiety and depression lift within an few days of proper tx. I printed off your list of suggestions in case I reach a low point again that can't be overcome by increasing my remeron dose. Thanks so much.
cole
Posted by dreamer on January 14, 2001, at 2:26:25
In reply to Reboxitine / Edronax, posted by HenryO on January 3, 2001, at 0:56:28
been on 4mg twice a day of reboxetine for about 2 years to combat the tiredness from efexor xr 75mg.for the first 3 days i experienced severe anxiety and cried alot and barked at alot of people,then after the 3 days i felt a little too high then this gradually eased and i became more interested in day to day activities spending less time in bed.
its not a miracle worker,its very subtle and clever you just find yourself noticing that your more interested in whats going on in the world or more active at work.
i still get periods of tiredness and depressed but not as severe as too end my life i also tend to get very high but all this is due to the fact that i do not take a mood stabliser, its as if my mood disorder is running in the background and is being filtered by the anti anxiety effects of the drug,hey i have no worries!
as for side effects of reboxetine well i dont have any and it seemes to have restored my libido
so stay in bed and shout at the tv for the first few days,much luck.
This is the end of the thread.
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