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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Tori on October 2, 2000, at 4:36:27
Hi there,
Dx manic depressive/major depressive disorder or whatever it is called March 00, have been depressed for years but the manic part didn't kick in until my mom did three years ago really young from cancer (40).
First, a lowdown on my current meds:
started Parnate on 25 Sept, 10 mg bid.
Lamictal (Lamotrigine) 150 bid
Clonazepam prn
Restoril 30 - 60 - 90 mg prn
multi-vitaminI have been on Parnate now for a week. It kicked in on day four; unbelievable; the day before I was 8/10 on wanting to commit suicide three times that day (it took a hell of a lot out of me to get those thoughts out of my head) and the next day -- NOTHING!!! :-) :-) :-) NO THOUGHTS AT ALL!!!! The three weeks beforehand I went through horrible, horrible W/D from the celexa 40 mg and wellbutrin 300 mg; I was off work for two weeks because of it. I'm going back to work this morning. ((crap!!!))
I take it at 7 a.m. and 7 p.m. I was taking it at 2 p.m. before. I can't sleep. Tonight for example I had a hard time sleeping the night before but got up at 10 anyways (4 hours sleep), walked for 30 minutes, did errands, had lots of energy which was a blessing as I had been on a combo for months that left me lethargic and exhausted.
Went to bed at 9:30 tonight; took 4 mg clonazepam and 30 mg restoril. Woke up two hours later; ate some cereal, back to bed. Woke up at 2:11; took 60 mg Restoril (man I'm building a tolerance to this stuff). Still wide awake as I type this.
QUESTION -- can I just take the full dose in the morning. Why the spanned dosage during the day? I have heard of possibilities of hypertension when increasing dosages but I don't think that moving the 10 mg to an earlier timeslot would kill me. I have been keeping track of my BP and it has caused some hypotension but I haven't really noticed anything negative.
Any suggestions? And also, when should the dosage be increased if required? If it works at 20 should I stick to that?
I have a great GP who has a lot of knowledge of all AD"s and a shrink that doesn't .... and before with SSRI's and the like I would fiddle with them myself but with MAOI's I'm not even going close to modifying them on my own without prior approval. I haven't read anything here or on ASDM or on the net about insomnia......anybody with any guidance in this area?
Greatly appreciated if anybody could help. Thanks!!!!!!!
Posted by Seamus2 on October 2, 2000, at 10:04:16
In reply to INSOMNIA - Parnate 10 mg bid - PLEASE HELP!, posted by Tori on October 2, 2000, at 4:36:27
Tori,
You could try taking the 20 mgs at one shot in the morning, but I found it too stimulating, esp. with a couple cups of coffee.
I think the second dose at 7 pm is what's causing the problem. Try taking the second dose at 1 or 2 pm in the afternoon. Also, no caffeine after 2 pm! (that was a must for me)
I found that I needed less sleep on Parnate, period. 6.5 - 7 hours was fine, and more tended to make me less motivated the next day.
After 8 years on the Parnate, I've recently switched to Amisulpride 50 mgs per day on AndrewB and SLS's recommendations. My reaction: amazing stuff. I'm not sure if it's even working, but I suspect something's going on because the weepiness and self-castigation I experienced during the month-long washout from Parnate has abated. Winter will be the touchstone because I've had SADD long before they even invented the term. How I used to dread October-Feb.
To tell the truth, each year I would have to promise myself not to kill myself until March 1st. Seeing as it's October 2, even the idea of making that promise is foreign to me; so something must be going on! I guess the test would be to discontinue the Amisulpride -- but not this year.
Regards,
Seamus
Posted by SLS on October 2, 2000, at 11:01:04
In reply to Re: INSOMNIA - Parnate 10 mg bid - PLEASE HELP!, posted by Seamus2 on October 2, 2000, at 10:04:16
> Tori,
>
> You could try taking the 20 mgs at one shot in the morning, but I found it too stimulating, esp. with a couple cups of coffee.
>
> I think the second dose at 7 pm is what's causing the problem. Try taking the second dose at 1 or 2 pm in the afternoon. Also, no caffeine after 2 pm! (that was a must for me)
>
> I found that I needed less sleep on Parnate, period. 6.5 - 7 hours was fine, and more tended to make me less motivated the next day.
>
> After 8 years on the Parnate, I've recently switched to Amisulpride 50 mgs per day on AndrewB and SLS's recommendations. My reaction: amazing stuff. I'm not sure if it's even working, but I suspect something's going on because the weepiness and self-castigation I experienced during the month-long washout from Parnate has abated. Winter will be the touchstone because I've had SADD long before they even invented the term. How I used to dread October-Feb.
>
> To tell the truth, each year I would have to promise myself not to kill myself until March 1st. Seeing as it's October 2, even the idea of making that promise is foreign to me; so something must be going on! I guess the test would be to discontinue the Amisulpride -- but not this year.
>
> Regards,
>
> Seamus
Insomnia can be mitigated by not taking Parnate after 3:00pm.Taking half of your Parnate in the morning and the other half between noon and 2:00pm should help.
The other day, I forgot to take my last dosage of Parnate. I realized this just before going to bed at 10:30pm, so I swallowed 20mg. I did not sleep a single second that night.
- Scott
Posted by Tori on October 2, 2000, at 18:49:09
In reply to INSOMNIA - Parnate 10 mg bid - PLEASE HELP!, posted by Tori on October 2, 2000, at 4:36:27
SEAMUS2 and SLS - Thanks for your responses!
Last night was brutal. And trying to stay awake at work today was even worse. I took my second dose today around 1:00, first dose was at 6 a.m. I'm worried that I will fall asleep driving home, I'm THAT tired. I will try your suggestions as I moved the dose by myself and I'm not dying of hypertension so that's OK. Also, I don't consume caffeine as specified in the diet (I drank too much of it anyways and will have enough money for a G4 in a month from the savings of not going to Starbucks!!!) so that makes matters worse ... but one thing I have noticed, is that when I take coedine, it makes me WIRED!!! ... oh poop, it just occured to me there is caffeine in tynelol 3's!
Hopefully this will all settle down and I'll feel normal again. This morning I felt like a wired poodle driving to work as I had a headache and yes, took some coedine.
Funny thing is, taking this stuff is making me not want to smoke anymore as when I have one my head pounds so much it's not worth it! But when I was on Wellbutrin, aka Zyprexa or that anti-smoking med, I was smoking over a pack a day!!! Go figure.
Thanks for your prompt responses. :-)
Posted by curran on October 2, 2000, at 20:23:24
In reply to Re: INSOMNIA - Parnate 10 mg bid Thanks!! » Tori, posted by Tori on October 2, 2000, at 18:49:09
> SEAMUS2 and SLS - Thanks for your responses!
>
> Last night was brutal. And trying to stay awake at work today was even worse. I took my second dose today around 1:00, first dose was at 6 a.m. I'm worried that I will fall asleep driving home, I'm THAT tired. I will try your suggestions as I moved the dose by myself and I'm not dying of hypertension so that's OK. Also, I don't consume caffeine as specified in the diet (I drank too much of it anyways and will have enough money for a G4 in a month from the savings of not going to Starbucks!!!) so that makes matters worse ... but one thing I have noticed, is that when I take coedine, it makes me WIRED!!! ... oh poop, it just occured to me there is caffeine in tynelol 3's!
>
> Hopefully this will all settle down and I'll feel normal again. This morning I felt like a wired poodle driving to work as I had a headache and yes, took some coedine.
>
> Funny thing is, taking this stuff is making me not want to smoke anymore as when I have one my head pounds so much it's not worth it! But when I was on Wellbutrin, aka Zyprexa or that anti-smoking med, I was smoking over a pack a day!!! Go figure.
>
> Thanks for your prompt responses. :-)Am a long-time Parnate user. I take a very small amount of Trazadone (Deseryl) at night. It gets me to sleep, and is safe to take with Parnate. I promise you, that's your answer. Deseryl, while an anti-depressant, is better as a non-addicting sleep aid than as a depressant. Take too much of it and you're worn out. I bite off a little chunk and that gets me to sleep.
Posted by Tori on October 3, 2000, at 3:01:32
In reply to Re: INSOMNIA - Parnate 10 mg bid Thanks!!, posted by curran on October 2, 2000, at 20:23:24
Hi Curran,
Unfortunately I can't take trazodone -- when I was on it I had two horrible thunderclap headaches that i had never experienced in my life before that sent me to the ER-
the first time I came home from a walk, sat down outside, lit a cigarette and the first inhale it happened like that -- BAM! Ambulane was called; my friend at the time gave me some of her percocet which didn't help; I have never been in so much pain in my LIFE. Head felt like it was going to explode, was kicking my legs, howling in pain; took me to the ER and did a scan on my melon and a spinal tap and gave me the right painkillers but didn't find anything;
Second time it happened a week later -- I was brushing my teeth and cleaning my tongue and I gagged and BUH-BAM!!, the headache hit again, ambulance again ....whoohooo whooohhoo whoohoo.... the moronic doctor on duty said it was a migraine (which it wasn't) and left me there for five hours to suffer in pain while he gave me "migraine medicine" which he "knew" would work. So I lay there for that period of time agonizing in pain and you know what? They wouldn't even give me morphine or any painkillers before I went home; he threw me some tylenol 3's (which are like candy to me). They knew I was in the mental unit and I firmly believe that they were discriminating against me, thinking I was someone trying to get attention or some opiate junkie. I hate ER's. Oh yeah, and it took an hour for a nurse to finally give me a blanket after I'm laying under one sheet, freezing my ass off. Thank god we have a health care system in Canada, but it's deteriorating badly (feds won't transfer med payments to provinces, massive cutbacks in services, yadda yadda).
Once I stopped the trazodone they stopped as well and I swore I would never touch the stuff again (as well as Paxil). It also rendered me COMPLETELY unstable and in a vegetative state when I took it, no matter what the dose, and when I was in the mental hospital the night nurses overdosed me on it and the next day I couldn't walk or function whatsoever.
Went to a neurologist after that and he was completely useless. Buddy, it was the trazodone! Trazodone=headaches, no trazodone=no headaches. He was a waste of carbon I'll tell ya that....
I wonder if I can take Zoplicon again (if that's the correct name); only side effect was a horrible taste in my mouth the rest of the day but I heard it can be alleviated by drinking citrus the night before (????).
Today I was so tired at work, I had to sit in the bathroom and go to sleep for about fifteen minutes ... came home at 6 and slept until now, just woke up ... but at least I got those 6 hours!!!! :)
Tomorrow I'll take the Parnate at noon so it would be six hours apart. Let's hope this works. I don't want to be dependent on taking sleeping meds for the rest of my life. It's hard enough being on these drugs ....
Thanks again!
Posted by pullmarine on October 12, 2000, at 0:08:28
In reply to INSOMNIA - Parnate 10 mg bid - PLEASE HELP!, posted by Tori on October 2, 2000, at 4:36:27
try taking 2 nyquils
john
> Hi there,
>
> Dx manic depressive/major depressive disorder or whatever it is called March 00, have been depressed for years but the manic part didn't kick in until my mom did three years ago really young from cancer (40).
>
> First, a lowdown on my current meds:
>
> started Parnate on 25 Sept, 10 mg bid.
> Lamictal (Lamotrigine) 150 bid
> Clonazepam prn
> Restoril 30 - 60 - 90 mg prn
> multi-vitamin
>
> I have been on Parnate now for a week. It kicked in on day four; unbelievable; the day before I was 8/10 on wanting to commit suicide three times that day (it took a hell of a lot out of me to get those thoughts out of my head) and the next day -- NOTHING!!! :-) :-) :-) NO THOUGHTS AT ALL!!!! The three weeks beforehand I went through horrible, horrible W/D from the celexa 40 mg and wellbutrin 300 mg; I was off work for two weeks because of it. I'm going back to work this morning. ((crap!!!))
>
> I take it at 7 a.m. and 7 p.m. I was taking it at 2 p.m. before. I can't sleep. Tonight for example I had a hard time sleeping the night before but got up at 10 anyways (4 hours sleep), walked for 30 minutes, did errands, had lots of energy which was a blessing as I had been on a combo for months that left me lethargic and exhausted.
>
> Went to bed at 9:30 tonight; took 4 mg clonazepam and 30 mg restoril. Woke up two hours later; ate some cereal, back to bed. Woke up at 2:11; took 60 mg Restoril (man I'm building a tolerance to this stuff). Still wide awake as I type this.
>
> QUESTION -- can I just take the full dose in the morning. Why the spanned dosage during the day? I have heard of possibilities of hypertension when increasing dosages but I don't think that moving the 10 mg to an earlier timeslot would kill me. I have been keeping track of my BP and it has caused some hypotension but I haven't really noticed anything negative.
>
> Any suggestions? And also, when should the dosage be increased if required? If it works at 20 should I stick to that?
>
> I have a great GP who has a lot of knowledge of all AD"s and a shrink that doesn't .... and before with SSRI's and the like I would fiddle with them myself but with MAOI's I'm not even going close to modifying them on my own without prior approval. I haven't read anything here or on ASDM or on the net about insomnia......anybody with any guidance in this area?
>
> Greatly appreciated if anybody could help. Thanks!!!!!!!
Posted by Tori on October 12, 2000, at 1:45:43
In reply to Re: INSOMNIA - Parnate 10 mg bid - PLEASE HELP!, posted by pullmarine on October 12, 2000, at 0:08:28
> try taking 2 nyquils
>
> johnHi John,
Taking the Parnate at 6 a.m. and noon has seemed to alleviate the problem for the time being.
Thanks for writing!
This is the end of the thread.
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