Psycho-Babble Medication Thread 28776

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Wellbutrin and Serzone

Posted by MHK on April 3, 2000, at 18:28:50

Has anybody had experience specifically combining Wellbutrin and Serzone? I've had good results with Wellbutrin in the past for major depression, but it didn't really do the trick for my long-term (decades)dysthymia. Recently, I read that the two make a good combination.

I'm getting ready to go back on meds after an extended absence and I'd very much like some real world input.

Thanks so much for anything you can offer.

 

Re: Wellbutrin and Serzone

Posted by CT on April 4, 2000, at 10:38:02

In reply to Wellbutrin and Serzone, posted by MHK on April 3, 2000, at 18:28:50

> Has anybody had experience specifically combining Wellbutrin and Serzone? I've had good results with Wellbutrin in the past for major depression, but it didn't really do the trick for my long-term (decades)dysthymia. Recently, I read that the two make a good combination.
>
> I'm getting ready to go back on meds after an extended absence and I'd very much like some real world input.
>
> Thanks so much for anything you can offer.

I was on Serzone for 8 months, the last 3 months I was taking 600mg at night. As long as I was increasing my Serzone I did fine, but once I leveled out my depression symptoms returned. My Doctor prescribed Wellbutrin to augment the Serzone and I was so hopeful. I had a very bad reaction after taking just a few doses of Wellbutrin that I stopped taking it. I was extremely confused, hallucinated and would hear weird noises along with my arms being numb and having a sensation of being hot and cold at the same time.
2 months ago I switched from Serzone to Zoloft and I starting to feel fantastic!!! I do know that my experience is a unique one and does in no way mirror or mimic yours or anyone elses experience. I too consulted this board with same question as yours - Has anyone else been on this combination. I got a reply from either John L or Cam who indicated that this drug combo is not common at all, but makes absolute sense that these 2 drugs would compliment each other.
Sorry this is so long. I wish you well and let us know how this all goes for you!! Take care!!

 

Re: Wellbutrin and Serzone

Posted by MHK on April 4, 2000, at 17:34:46

In reply to Re: Wellbutrin and Serzone, posted by CT on April 4, 2000, at 10:38:02

----------------
I had a very bad reaction after taking just a few doses of Wellbutrin that I stopped taking it. I was extremely confused, hallucinated and would hear weird noises along with my arms being numb and having a sensation of being hot and cold at the same time.
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Sorry to hear you had such a bad experience with Wellbutrin. It really is amazing how different people's reactions can be.

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2 months ago I switched from Serzone to Zoloft and I starting to feel fantastic!!!
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That's wonderful! I'm very happy for you. I hope it continues to keep you feeling good and I hope I can find something as effective for myself.

Thanks for the information and your good wishes.

Take care.

 

Re: Wellbutrin and Serzone

Posted by Lance on April 4, 2000, at 21:52:48

In reply to Re: Wellbutrin and Serzone, posted by MHK on April 4, 2000, at 17:34:46

I added WB to my Serzone with the ambivalent consent of my pdoc to help offset the droney effects and lack of any vitality. My reaction was somewhat unique also in that it was great at first: improved sex drive, better concentration, more driven, more vital, more confiedence, less nervous around people.

Then the racy thoughts returned that I got on Serzone to stop. I could not concentrate on my work, and I had trouble finding simple words. The WB appears to have exacerbated problems with rage (I guess a metabolite of Serzone is to blame, made worse by the WB).

Aside from all that, I liked it. But I had to come off. I still take it on the weekends when I need to interact socially and not be the boring "stormcloud" guy. I'm thinking of switching back to an SSRI like Celexa and maybe adding the WB at 75 mg to offset the Celexa side effects. Serzone cannot release me from the terrible, unredeemable thoughts about myself.

Mixing WB and Serzone appears to be a crapshoot depending on your chemistry. But many report the effects after 3 mos. is different (better or worse) from after the first couple of weeks.


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