![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 90 to 114 of 147. Go back in thread:
Posted by Phillipa on March 24, 2018, at 20:23:57
In reply to Re: How can I block Cortisol?, posted by farshad on March 24, 2018, at 20:18:09
A psychiatric hospital? Is this what you meant to write? Phillipa
Posted by farshad on March 24, 2018, at 20:27:07
In reply to Re: How can I block Cortisol? » farshad, posted by Phillipa on March 24, 2018, at 20:23:57
> A psychiatric hospital? Is this what you meant to write? Phillipa
maybe but it was very small.. not sure what it was. well anyway I went there and i talked to them for a few hours and I got zyprexa then went home the same day.
Posted by ed_uk2010 on March 24, 2018, at 20:35:05
In reply to Re: How can I block Cortisol?, posted by farshad on March 24, 2018, at 20:16:53
I did wonder what you meant my imaginary places :)
It sounds like an urgent care centre for mental health, right?
It's common for people with depression + anxiety/agitation to be calmed by olanzapine (Zyprexa) or a small amount of risperidone (Risperdal). The dose of risperidone used in non-psychotic illness is usually very small.
Posted by farshad on March 24, 2018, at 20:41:21
In reply to Re: How can I block Cortisol?, posted by ed_uk2010 on March 24, 2018, at 20:35:05
> I did wonder what you meant my imaginary places :)
>
> It sounds like an urgent care centre for mental health, right?
>
> It's common for people with depression + anxiety/agitation to be calmed by olanzapine (Zyprexa) or a small amount of risperidone (Risperdal). The dose of risperidone used in non-psychotic illness is usually very small.
>
>
>
>
>So what should I do man? is it possible to get zyprexa from the family doctor?
Also I wanna do a cortisol test. You say you cant test for CRH but can you test ACTH? is not really not possible to measure CRF1
Posted by farshad on March 24, 2018, at 20:42:10
In reply to Re: How can I block Cortisol?, posted by farshad on March 24, 2018, at 20:41:21
> > I did wonder what you meant my imaginary places :)
> >
> > It sounds like an urgent care centre for mental health, right?
> >
> > It's common for people with depression + anxiety/agitation to be calmed by olanzapine (Zyprexa) or a small amount of risperidone (Risperdal). The dose of risperidone used in non-psychotic illness is usually very small.
> >
> >
> >
> >
> >
>
> So what should I do man? is it possible to get zyprexa from the family doctor?
> Also I wanna do a cortisol test. You say you cant test for CRH but can you test ACTH? is not really not possible to measure CRF1``Is it really not possible to measure CRF1 is what I meant
Posted by ed_uk2010 on March 24, 2018, at 21:11:12
In reply to Re: How can I block Cortisol?, posted by farshad on March 24, 2018, at 20:41:21
>is it possible to get zyprexa from the family doctor?
Potentially. It is more common to get olanzapine from a psychiatrist.
I don't think it's appropriate to take antipsychotics with pramipexole. You might want to look at reducing and stopping that.
>You say you cant test for CRH but can you test ACTH? is not really not possible to measure CRF1CRF-1 is a receptor. You cannot test for receptors using a blood test.
Posted by farshad on March 24, 2018, at 21:23:38
In reply to Re: How can I block Cortisol?, posted by ed_uk2010 on March 24, 2018, at 21:11:12
> >is it possible to get zyprexa from the family doctor?
>
> Potentially. It is more common to get olanzapine from a psychiatrist.
>
> I don't think it's appropriate to take antipsychotics with pramipexole. You might want to look at reducing and stopping that.
>
>
> >You say you cant test for CRH but can you test ACTH? is not really not possible to measure CRF1
>
> CRF-1 is a receptor. You cannot test for receptors using a blood test.oh okay. Why can I not take zyprexa with prami? Its not the dopamine antagonism of the antipsychotic im out for its bcus it inhibits CRH. Is it just becuase it would be dangerous? Im willing to quit prami tho no problem... Im currently on 4 meds , I can quit the 3 I get online (prami, armmodafinil and selegline) and I get wellbutrin from my doc . So wellbutrin + zyprexa it will be then... But i doubt I will get zyprexa..
So I have to do a MRI scan for the CRF1? got it..
Posted by Farshad on March 24, 2018, at 22:08:13
In reply to Re: How can I block Cortisol?, posted by farshad on March 24, 2018, at 21:23:38
> > >is it possible to get zyprexa from the family doctor?
> >
> > Potentially. It is more common to get olanzapine from a psychiatrist.
> >
> > I don't think it's appropriate to take antipsychotics with pramipexole. You might want to look at reducing and stopping that.
> >
> >
> > >You say you cant test for CRH but can you test ACTH? is not really not possible to measure CRF1
> >
> > CRF-1 is a receptor. You cannot test for receptors using a blood test.
>
> oh okay. Why can I not take zyprexa with prami? Its not the dopamine antagonism of the antipsychotic im out for its bcus it inhibits CRH. Is it just becuase it would be dangerous? Im willing to quit prami tho no problem... Im currently on 4 meds , I can quit the 3 I get online (prami, armmodafinil and selegline) and I get wellbutrin from my doc . So wellbutrin + zyprexa it will be then... But i doubt I will get zyprexa..
>
> So I have to do a MRI scan for the CRF1? got it..anyway thanks for all the help. just 1 last thing..Inhibiting crh will inhibit crf 1 and 2 also right
Posted by ed_uk2010 on March 25, 2018, at 9:52:36
In reply to Re: How can I block Cortisol?, posted by farshad on March 24, 2018, at 21:23:38
Hi,
>Its not the dopamine antagonism of the antipsychotic im out for its bcus it inhibits CRH.
Olanzapine (Zyprexa) acts at many receptors, so it's not possible to be so specific about why it can relieve agitation.
You said you found it calming before - after a single dose, I believe? That was probably due to action at multiple receptors, and not necessarily related to CRH.
>Is it just becuase it would be dangerous? Im willing to quit prami tho no problem... Im currently on 4 meds , I can quit the 3 I get online (prami, armmodafinil and selegline)
Taking strange combinations like pramipexole with olanzapine is really unknown territory. You don't want to make yourself more ill.
Pramipexole should not be stopped suddenly. Reduce gradually.
>and I get wellbutrin from my doc . So wellbutrin + zyprexa it will be then... But i doubt I will get zyprexa...
This is something you can speak to your doctor about. A lot of people find that olanzapine (Zyprexa) calms severe agitation after a small dose. Since a doctor has given it to you before, you can mention this.
For schizophrenia, olanzapine is taken every day. For relief of agitation in depressive illness, it is usually short-term.
A major issue with olanzapine is that some users gain a lot of weight.
>So I have to do a MRI scan for the CRF1?
No sorry, this wouldn't show on a MRI. Routine medical tests and scans do not show the function of this receptor.
As you know, there has been research into the possible role of CRF-1 receptors in mental health conditions . Much of the research has been on rats, but there have been some clinical trials in humans. As far as I can see, some trials showed possible evidence of efficacy, whereas others did not. As an example, a trial of pexacerfont, a selective CRF-1 receptor antagonist, found that it was not effective for generalised anxiety.
So, although a few CRF-1 antagonists have been developed by pharmaceutical companies such as GSK and BMS, it isn't entirely clear what they might be most useful for in humans.
Posted by farshad on March 25, 2018, at 17:06:47
In reply to Re: How can I block Cortisol? » farshad, posted by ed_uk2010 on March 25, 2018, at 9:52:36
> Hi,
>
> >Its not the dopamine antagonism of the antipsychotic im out for its bcus it inhibits CRH.
>
> Olanzapine (Zyprexa) acts at many receptors, so it's not possible to be so specific about why it can relieve agitation.
>
> You said you found it calming before - after a single dose, I believe? That was probably due to action at multiple receptors, and not necessarily related to CRH.
>
> >Is it just becuase it would be dangerous? Im willing to quit prami tho no problem... Im currently on 4 meds , I can quit the 3 I get online (prami, armmodafinil and selegline)
>
> Taking strange combinations like pramipexole with olanzapine is really unknown territory. You don't want to make yourself more ill.
>
> Pramipexole should not be stopped suddenly. Reduce gradually.
>
> >and I get wellbutrin from my doc . So wellbutrin + zyprexa it will be then... But i doubt I will get zyprexa...
>
> This is something you can speak to your doctor about. A lot of people find that olanzapine (Zyprexa) calms severe agitation after a small dose. Since a doctor has given it to you before, you can mention this.
>
> For schizophrenia, olanzapine is taken every day. For relief of agitation in depressive illness, it is usually short-term.
>
> A major issue with olanzapine is that some users gain a lot of weight.
>
> >So I have to do a MRI scan for the CRF1?
>
> No sorry, this wouldn't show on a MRI. Routine medical tests and scans do not show the function of this receptor.
>
> As you know, there has been research into the possible role of CRF-1 receptors in mental health conditions . Much of the research has been on rats, but there have been some clinical trials in humans. As far as I can see, some trials showed possible evidence of efficacy, whereas others did not. As an example, a trial of pexacerfont, a selective CRF-1 receptor antagonist, found that it was not effective for generalised anxiety.
>
> So, although a few CRF-1 antagonists have been developed by pharmaceutical companies such as GSK and BMS, it isn't entirely clear what they might be most useful for in humans.
>
>If I went on zyprexa since its an antagonist on the dopamine receptors and many others, would my body evnetually upregulate them? Since I heard if you use an agonist on a receptor too much your body starts decreasing the activity and if you block something too much your body starts increasing . is that true?
Posted by ed_uk2010 on March 25, 2018, at 17:25:52
In reply to Re: How can I block Cortisol?, posted by farshad on March 25, 2018, at 17:06:47
>If I went on zyprexa since its an antagonist on the dopamine receptors and many others, would my body evnetually upregulate them? Since I heard if you use an agonist on a receptor too much your body starts decreasing the activity and if you block something too much your body starts increasing . is that true?
Hi F,
There can be truth in that for some drugs. This can lead to unexpected effects. As an example, people who take benzodiazepines or opioids regularly can experience a reduction in effectiveness.
With antipsychotics, there is a theory that taking potent dopamine D2 receptor antagonists long term can lead to receptor upregulation. This may be a cause of tardive dyskinesia.
With olanzapine (Zyprexa) at low doses, and in younger people, tardive dyskinesia is not a high risk. The main risks are due to weight gain and associated metabolic issues.
Although I can't make any definitive suggestions for yourself because I don't know much about your medical and psychiatric problems, I can say that some people with agitated depression find small doses of olanzapine very calming, although it can be sedating initially. I'm unsure what you most want from a medication...
Posted by ed_uk2010 on March 30, 2018, at 14:46:01
In reply to Re: How can I block Cortisol?, posted by farshad on March 25, 2018, at 17:06:47
Hi Farshad,
How are you doing? Did you see your doctor to ask about tests, or maybe olanzapine?
Posted by farshad on March 31, 2018, at 0:25:48
In reply to Re: How are you doing? » farshad, posted by ed_uk2010 on March 30, 2018, at 14:46:01
> Hi Farshad,
>
> How are you doing? Did you see your doctor to ask about tests, or maybe olanzapine?Not yet my appointment is on 5 april. I have come to different conclusions now.. I think I have a tumor in the paraventricular nucleus that constantly releases CRH . So Im gonna ask for an MRI scan. Zyprexa Inhibits CRH. So if I do have a tumor I will get gamma knife surgery but if I cant for some reason have that particular surgery, since I dont want them to open my skull I will ask for medication that can help against the tumor and with that I will also ask my doctor for Zyprexa since thats the only drug that ever worked for my anxiety. Thats where I am at now. Now just waiting and trying to learn stuff about my situation.
Posted by SLS on March 31, 2018, at 6:08:49
In reply to Re: How are you doing?, posted by farshad on March 31, 2018, at 0:25:48
> I have come to different conclusions now.. I think I have a tumor in the paraventricular nucleus that constantly releases CRH.
That's an interesting conclusion. How did you come to it?
- Scott
Posted by farshad on March 31, 2018, at 6:55:10
In reply to Re: How are you doing? » farshad, posted by SLS on March 31, 2018, at 6:08:49
> > I have come to different conclusions now.. I think I have a tumor in the paraventricular nucleus that constantly releases CRH.
>
> That's an interesting conclusion. How did you come to it?
>
>
> - ScottCause thats the only way I can possibly have excess CRH release is if a tumor is there. Becuase the body is made in such a way that it wouldnt happen unless theres a tumor.
Also I have some symtomps of tumor. You can ask me what my symtomps are and I can tell you but at the end of the day its not gonna prove anything.After the MRI scan I can come back and tell you guys if I have a tumor or not if anyone cares, Just reply to this topic and I wil get a email notification .
Posted by SLS on March 31, 2018, at 8:17:37
In reply to Re: How are you doing?, posted by farshad on March 31, 2018, at 6:55:10
> > > I have come to different conclusions now.. I think I have a tumor in the paraventricular nucleus that constantly releases CRH.
> >
> > That's an interesting conclusion. How did you come to it?
> >
> >
> > - Scott
>
> Cause thats the only way I can possibly have excess CRH release is if a tumor is there. Becuase the body is made in such a way that it wouldnt happen unless theres a tumor.
> Also I have some symtomps of tumor. You can ask me what my symtomps are and I can tell you but at the end of the day its not gonna prove anything.After the MRI scan I can come back and tell you guys if I have a tumor or not if anyone cares, Just reply to this topic and I wil get a email notificationHave you tested positive for the dexamethasone suppression test (DST)?
I think a lot of people care and would like to see you find a way to feel better.
- Scott
Posted by farshad on March 31, 2018, at 8:51:29
In reply to Re: How are you doing? » farshad, posted by SLS on March 31, 2018, at 8:17:37
> > > > I have come to different conclusions now.. I think I have a tumor in the paraventricular nucleus that constantly releases CRH.
> > >
> > > That's an interesting conclusion. How did you come to it?
> > >
> > >
> > > - Scott
> >
> > Cause thats the only way I can possibly have excess CRH release is if a tumor is there. Becuase the body is made in such a way that it wouldnt happen unless theres a tumor.
> > Also I have some symtomps of tumor. You can ask me what my symtomps are and I can tell you but at the end of the day its not gonna prove anything.After the MRI scan I can come back and tell you guys if I have a tumor or not if anyone cares, Just reply to this topic and I wil get a email notification
>
> Have you tested positive for the dexamethasone suppression test (DST)?
>
> I think a lot of people care and would like to see you find a way to feel better.
>
>
> - Scottno. what is the dexamethasone test?
Posted by SLS on March 31, 2018, at 13:00:54
In reply to Re: How are you doing?, posted by farshad on March 31, 2018, at 8:51:29
> > > > > I have come to different conclusions now.. I think I have a tumor in the paraventricular nucleus that constantly releases CRH.
> > > > That's an interesting conclusion. How did you come to it?
> > > Cause thats the only way I can possibly have excess CRH release is if a tumor is there. Becuase the body is made in such a way that it wouldnt happen unless theres a tumor.
> > > Also I have some symtomps of tumor. You can ask me what my symtomps are and I can tell you but at the end of the day its not gonna prove anything.After the MRI scan I can come back and tell you guys if I have a tumor or not if anyone cares, Just reply to this topic and I wil get a email notification> > Have you tested positive for the dexamethasone suppression test (DST)?
> >
> > I think a lot of people care and would like to see you find a way to feel better.> no. what is the dexamethasone test?
Dexamethasone is a synthetic corticosteroid that normally shuts off cortisol production via negative-feedback loops involving ACTH and CRH. Adiministering dexamethasone is a way to determine if your cortisol negative feedback loops are operating properly.
I was just curious. I don't know how the results of such a test would assess CRH secreting tumors.
- Scott
Posted by ed_uk2010 on March 31, 2018, at 13:06:51
In reply to Re: How are you doing?, posted by farshad on March 31, 2018, at 0:25:48
Hi Farshad,
Yes, people do care. If they didn't, they wouldn't be asking about you or logging on to have a conversation. It's also good that you have an appointment soon.
>I think I have a tumor in the paraventricular nucleus that constantly releases CRH.
To be absolutely honest, it is extremely unlikely that you have a brain tumour. I'm not sure why you would think that you do. You haven't mentioned any test so far that suggests you have a tumour releasing CRH. The genetic tests you did from an online source certainly don't suggest this.
I think it's important to make it clear that finding Zyprexa calming does not in any way prove that you have elevated CRH. A very high proportion of people find Zyprexa calming irrespective of CRH. Plus, a lot of people find Zyprexa calming even when other meds haven't helped.
From what you say, you seem to have had mental health symptoms for a long time, not just recently. Am I right? Brain tumours do not cause long term mental health symptoms in isolation.... This is because, if a brain tumour was the cause of your mental health symptoms, you would have been physically very ill a long time ago.
>So Im gonna ask for an MRI scan.
I think you would find that reassuring, but it's not the first step....
First of all, if you have neurological symptoms such as visual loss, you doctor would do a neurological examination. As a rule, people with rapid onset neurological symptoms over a few weeks would usually have an MRI. If you have had mental health symptoms for several years and no neurological dysfunction, this would not usually be a reason to do an MRI.
>I do have a tumor I will get gamma knife surgery but if I cant for some reason have that particular surgery, since I dont want them to open my skull.
Gamma Knife isn't actually surgery. It does not involve opening the skull. Gamma Knife is a special type of radiotherapy (radiation treatment) for brain cancers. From what you had said, there isn't any reason why you should think you have cancer though.
I think you should discuss all your concerns with your doctor, and get an examination done to put your mind at rest. The doctor may also do some blood tests like you wanted before.
Posted by ed_uk2010 on March 31, 2018, at 13:27:25
In reply to Re: How are you doing?, posted by SLS on March 31, 2018, at 13:00:54
Hi Scott,
Just some information :)
So far, Farshad hasn't had any tests performed by his doctor to assess HPA axis function or cortisol levels. S/he had some form of rather unconventional genetic test which I think was obtained online.
>I don't know how the results of such a test would assess CRH secreting tumors.
A CRH-secreting tumour would cause dexamethasone non-suppression, and early morning cortisol would be very elevated. Usually, there would be substantial metabolic derangement too eg. hyperglycaemia, hypokalaemia etc. CRH-releasing tumours are an extremely rare cause of Cushing's Syndrome though - ectopic ACTH is much more common, usually from the pituitary.
Posted by farshad on April 1, 2018, at 2:15:22
In reply to Re: How are you doing? » farshad, posted by ed_uk2010 on March 31, 2018, at 13:06:51
> Hi Farshad,
>
> Yes, people do care. If they didn't, they wouldn't be asking about you or logging on to have a conversation. It's also good that you have an appointment soon.
>
> >I think I have a tumor in the paraventricular nucleus that constantly releases CRH.
>
> To be absolutely honest, it is extremely unlikely that you have a brain tumour. I'm not sure why you would think that you do. You haven't mentioned any test so far that suggests you have a tumour releasing CRH. The genetic tests you did from an online source certainly don't suggest this.
>
> I think it's important to make it clear that finding Zyprexa calming does not in any way prove that you have elevated CRH. A very high proportion of people find Zyprexa calming irrespective of CRH. Plus, a lot of people find Zyprexa calming even when other meds haven't helped.
>
> From what you say, you seem to have had mental health symptoms for a long time, not just recently. Am I right? Brain tumours do not cause long term mental health symptoms in isolation.... This is because, if a brain tumour was the cause of your mental health symptoms, you would have been physically very ill a long time ago.
>
> >So Im gonna ask for an MRI scan.
>
> I think you would find that reassuring, but it's not the first step....
>
> First of all, if you have neurological symptoms such as visual loss, you doctor would do a neurological examination. As a rule, people with rapid onset neurological symptoms over a few weeks would usually have an MRI. If you have had mental health symptoms for several years and no neurological dysfunction, this would not usually be a reason to do an MRI.
>
> >I do have a tumor I will get gamma knife surgery but if I cant for some reason have that particular surgery, since I dont want them to open my skull.
>
> Gamma Knife isn't actually surgery. It does not involve opening the skull. Gamma Knife is a special type of radiotherapy (radiation treatment) for brain cancers. From what you had said, there isn't any reason why you should think you have cancer though.
>
> I think you should discuss all your concerns with your doctor, and get an examination done to put your mind at rest. The doctor may also do some blood tests like you wanted before.
>Well like I said im not gonna argue with you if I have a tumor or not I will just have to see and find out.
I believe its a benign tumor (non cancerous) so it doesent spread anywhere and its just in one part of my brain in the paraventricular nucleus .
I believe I have had this since I was 10-11 years old.... the older I got the more anxiety I got this would make sense since this mean the tumor got bigger more cells built up and pressing the CRH harder..
I know gamma knife is radiotherapy . I maybe worded it wrong when I said surgery I thought you could call it a surgery since it invovles operating on a person from doctor. and I havent even told you my symtomps but here are some: blurry vision , loss of balance, headache/pressure, sometimes tinnitus to name a few..
I will discuss this with my doc but since You asked I thought I would explain where im at right now.
Posted by farshad on April 1, 2018, at 2:17:38
In reply to Re: How are you doing?, posted by farshad on April 1, 2018, at 2:15:22
> > Hi Farshad,
> >
> > Yes, people do care. If they didn't, they wouldn't be asking about you or logging on to have a conversation. It's also good that you have an appointment soon.
> >
> > >I think I have a tumor in the paraventricular nucleus that constantly releases CRH.
> >
> > To be absolutely honest, it is extremely unlikely that you have a brain tumour. I'm not sure why you would think that you do. You haven't mentioned any test so far that suggests you have a tumour releasing CRH. The genetic tests you did from an online source certainly don't suggest this.
> >
> > I think it's important to make it clear that finding Zyprexa calming does not in any way prove that you have elevated CRH. A very high proportion of people find Zyprexa calming irrespective of CRH. Plus, a lot of people find Zyprexa calming even when other meds haven't helped.
> >
> > From what you say, you seem to have had mental health symptoms for a long time, not just recently. Am I right? Brain tumours do not cause long term mental health symptoms in isolation.... This is because, if a brain tumour was the cause of your mental health symptoms, you would have been physically very ill a long time ago.
> >
> > >So Im gonna ask for an MRI scan.
> >
> > I think you would find that reassuring, but it's not the first step....
> >
> > First of all, if you have neurological symptoms such as visual loss, you doctor would do a neurological examination. As a rule, people with rapid onset neurological symptoms over a few weeks would usually have an MRI. If you have had mental health symptoms for several years and no neurological dysfunction, this would not usually be a reason to do an MRI.
> >
> > >I do have a tumor I will get gamma knife surgery but if I cant for some reason have that particular surgery, since I dont want them to open my skull.
> >
> > Gamma Knife isn't actually surgery. It does not involve opening the skull. Gamma Knife is a special type of radiotherapy (radiation treatment) for brain cancers. From what you had said, there isn't any reason why you should think you have cancer though.
> >
> > I think you should discuss all your concerns with your doctor, and get an examination done to put your mind at rest. The doctor may also do some blood tests like you wanted before.
> >
>
> Well like I said im not gonna argue with you if I have a tumor or not I will just have to see and find out.
>
> I believe its a benign tumor (non cancerous) so it doesent spread anywhere and its just in one part of my brain in the paraventricular nucleus .
>
> I believe I have had this since I was 10-11 years old.... the older I got the more anxiety I got this would make sense since this mean the tumor got bigger more cells built up and pressing the CRH harder..
>
> I know gamma knife is radiotherapy . I maybe worded it wrong when I said surgery I thought you could call it a surgery since it invovles operating on a person from doctor. and I havent even told you my symtomps but here are some: blurry vision , loss of balance, headache/pressure, sometimes tinnitus to name a few..
>
>
>
> I will discuss this with my doc but since You asked I thought I would explain where im at right now.
>wow my grammar is horrible... im just so tired.
Posted by ed_uk2010 on April 1, 2018, at 7:31:32
In reply to Re: How are you doing?, posted by farshad on April 1, 2018, at 2:15:22
Good luck at the doctor. Let us know how you get on.
If you had a CRH-secreting tumour since you were a child, you would have Cushing Syndrome at an advanced stage (assuming you are now an adult?). This would cause severe physical symptoms of a very widespread nature.
I'm not arguing :)
Posted by farshad on April 1, 2018, at 8:53:07
In reply to Re: How are you doing? » farshad, posted by ed_uk2010 on April 1, 2018, at 7:31:32
> Good luck at the doctor. Let us know how you get on.
>
> If you had a CRH-secreting tumour since you were a child, you would have Cushing Syndrome at an advanced stage (assuming you are now an adult?). This would cause severe physical symptoms of a very widespread nature.
>
> I'm not arguing :)But im saying I have a tumor in the paraventricular nucleus which releases CRH and CRH is a Peptide hormone . People with cushings have a tumor in the pituatary which releases constant cortisol and cortisol is a non peptide hormone and the effects would be very different wouldnt it? . isnt there a difference?
Im 20 now. Not arguing either just wanna understand stuff.
Posted by SLS on April 1, 2018, at 9:18:17
In reply to Re: How are you doing?, posted by farshad on April 1, 2018, at 2:15:22
> Well like I said im not gonna argue with you if I have a tumor or not I will just have to see and find out.
>
> I believe its a benign tumor (non cancerous) so it doesent spread anywhere and its just in one part of my brain in the paraventricular nucleus .
>
> I believe I have had this since I was 10-11 years old.... the older I got the more anxiety I got this would make sense since this mean the tumor got bigger more cells built up and pressing the CRH harder..
>
> I know gamma knife is radiotherapy . I maybe worded it wrong when I said surgery I thought you could call it a surgery since it invovles operating on a person from doctor. and I havent even told you my symtomps but here are some: blurry vision , loss of balance, headache/pressure, sometimes tinnitus to name a few..
>
>
>
> I will discuss this with my doc but since You asked I thought I would explain where im at right now.I hope you are able to come to a resolution of the syndrome you are experiencing. I guess it wouldn't hurt to have a MRI if that is what you need to do. Ed_UK gives good advice. I don't think he is challenging your intellect. He genuinely cares.
There might be some sort of dysautonomia thing going on. One of my doctors said that dysautonomia can be a component of depressive disorders, but symptoms are variable, and can include the symptoms you describe. Usually, it involves an imbalance of sympathetic/parasympathetic systems in favor of sympathetic. You would be in constant "fight-or-flight" mode. If your MRI is negative, you can then test your HPA axis function using low-dose dexamethasone suppression test or a dexamethasone/CRH test. If HPA is normal, then dysautonomia can explain high cortisol levels, if they exist. Major Depressive Disorder and bipolar depression often present with high cortisol levels. Do you have high cortisol levels? Do you have a depressive, anxiety, or OCD disorder as diagnosed by a doctor?
I must have missed your list of symptoms and diagnostic history.
- Scott
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