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Posted by Marilyn on April 6, 2001, at 5:51:15
In reply to Re: Are WE the real guinea-pigs?, posted by Seraphim on April 2, 2001, at 10:42:08
> Thanks Marilyn. Scary stuff. If you come across > more, please share it.
http://www.mall-net.com/mcs/p450.html
Marilyn
Posted by Marilyn on April 6, 2001, at 5:56:39
In reply to Re: Are WE the real guinea-pigs?, posted by Marilyn on April 6, 2001, at 5:51:15
http://www.geocities.com/HotSprings/3568/ATracyPhD.htm
Marilyn
Posted by Fish on April 6, 2001, at 8:10:27
In reply to Re: 7 WEEKS--EFFEXOR FREE, posted by JAMMER on April 5, 2001, at 18:35:42
Jammer, thanks for sharing information. Question ... the 18 mg, should that be taken every 3 days as the previous regimen, or everyday? Thanks Fish
Posted by JAMMER on April 6, 2001, at 9:07:28
In reply to Jammer - Question, posted by Fish on April 6, 2001, at 8:10:27
> Jammer, thanks for sharing information. Question ... the 18 mg, should that be taken every 3 days as the previous regimen, or everyday? Thanks Fish
Pharmacist stated every 3 days at 18mg, which is what I plan on doing. Doing well so far on 37.5mg every 3rd day now, another week, and I'll switch to 18mg every 3 days. If I start feeling weird I'll take a little Valium which helps calm me down, and I've found the Fioricet 1 tab ends the headache. And no brain shivers using this method, which is the best part...I thought the spike of 37mg every 4th day didn't make sense. Yes it reduces the frequency, but that spike on the day of taking the med seemed to be out of place. tapering the dose seems much more reasonable.
Your welcome,
-Jammer
Posted by JAMMER on April 6, 2001, at 12:49:06
In reply to Jammer - Question, posted by Fish on April 6, 2001, at 8:10:27
> Jammer, thanks for sharing information. Question ... the 18 mg, should that be taken every 3 days as the previous regimen, or everyday? Thanks Fish
Pharmacist stated every 3 days at 18mg, which is what I plan on doing. Doing well so far on 37.5mg every 3rd day now, another week, and I'll switch to 18mg every 3 days. If I start feeling weird I'll take a little Valium which helps calm me down, and I've found the Fioricet 1 tab ends the headache. And no brain shivers using this method, which is the best part...I thought the spike of 37mg every 4th day didn't make sense. Yes it reduces the frequency, but that spike on the day of taking the med seemed to be out of place. tapering the dose seems much more reasonable.
Your welcome,
-Jammer
Posted by willow on April 6, 2001, at 14:47:29
In reply to Re: 7 WEEKS--EFFEXOR FREE » JAMMER, posted by Quasibarbidoll on April 5, 2001, at 19:41:51
Quasi
"..I have lost some brain cells in this process.
Please tell me at 7 weeks that I will be my old normal self again.. sore from the fibro, but not
nutty."Concentration problems are common with fibro. I find the effexor has helped these symptoms, though it does nothing for muscle pain. Baclofen, light exercises, and therapy are also helping me with the symptoms. With the help of effexor I've been able to return to work on a part-time basis after being off for three years.
Best Wishes
Willow
Posted by Quasibarbidoll on April 6, 2001, at 19:06:43
In reply to Re: 7 WEEKS--EFFEXOR FREE, posted by willow on April 6, 2001, at 14:47:29
"
>
> Concentration problems are common with fibro. I find the effexor has helped these symptoms, though it does nothing for muscle pain. Baclofen, light exercises, and therapy are also helping me with the symptoms. With the help of effexor I've been able to return to work on a part-time basis after being off for three years.
>
> Best Wishes
> Willow
Thanks Willow!I have had fibro for 12 years, a mild case, thank heavans. I had sleep issues prior to taking effexor but none of the hideous effects that I have had since stopping Effexor.It's as though the drug(or withdrawel) has completely changed my tolerance for stress and wrecked my body physically. Had I known this, I would have taken a much different path 2 years ago.
Posted by Robin on April 6, 2001, at 19:29:25
In reply to Re: 7 WEEKS--EFFEXOR FREE, posted by Quasibarbidoll on April 6, 2001, at 19:06:43
Just thought I'd throw a positive story into the mix of withdrawl horror stories. So far, so good for me. I had been taking 150 mg for about 6 months, and about 2 weeks ago I decided to stop taking it. I dropped down to 75 mg which my doctor told me to take for two weeks. I'm supposed to drop down to 37.5 mg in a few days and hopefully it will go as well as the other cut back went. I can finally sit still without having something on me twitch, which was the worst side effect for me and one of the reasons why I'm stopping. It's so much easier now to fall asleep! I only had one bad experience with Effexor, and that happened after I failed to take my medicine for two days, which happened by accident! It was great for me until that terrifying night. It's obvious by reading the previous posts that Effexor has different effects on everyone. I decided to get off because I couldn't handle the constant twitching and moving and because I never want to have an experience like the one I had after not being able to take my medicine. Good luck to everyone on the drug and everyone trying to get of. Wish me luck too!
Robin
Posted by willow on April 6, 2001, at 20:13:03
In reply to Re: 7 WEEKS--EFFEXOR FREE, posted by Quasibarbidoll on April 6, 2001, at 19:06:43
"I had sleep issues prior ..."
My problem has been that I sleep too hard for too long. I am going to a sleep clinic on Tuesday night and hopefully they'll be able to give me some constructive feedback on how to get my sleep problems under control. (I have bad nighttime reflux and wasn't aware of it until recently and I twitch away in my sleep, which the effexor has made worse. I also start dreaming easily even when I'm awake) I do think poor sleep can bring on fibro. It will take a month to get feedback, (why so long?!?) and if there is anything useful I'll post it.
SWEET DREAMS
Willow
Posted by JAMMER on April 7, 2001, at 9:12:10
In reply to withdrawl going well, posted by Robin on April 6, 2001, at 19:29:25
> Just thought I'd throw a positive story into the mix of withdrawl horror stories. So far, so good for me. I had been taking 150 mg for about 6 months, and about 2 weeks ago I decided to stop taking it. I dropped down to 75 mg which my doctor told me to take for two weeks. I'm supposed to drop down to 37.5 mg in a few days and hopefully it will go as well as the other cut back went. I can finally sit still without having something on me twitch, which was the worst side effect for me and one of the reasons why I'm stopping. It's so much easier now to fall asleep! I only had one bad experience with Effexor, and that happened after I failed to take my medicine for two days, which happened by accident! It was great for me until that terrifying night. It's obvious by reading the previous posts that Effexor has different effects on everyone. I decided to get off because I couldn't handle the constant twitching and moving and because I never want to have an experience like the one I had after not being able to take my medicine. Good luck to everyone on the drug and everyone trying to get of. Wish me luck too!
>
> RobinRobin, Glad to hear your doing well in your tapering off plan. Once at 37mg don't get in a hurry. It has been reducing from this amount that I stated having issues. The "good" 2nd plan I was given by pharmacists is(as opposed to "bad" plan by my PCP):
Once at 37.5 for a few weeks, move to every other day for 2 weeks, then every 3rd day for 2 weeks, then open the cap, empty, and reinsert half ~18mg and take every 3rd day 2 weeks, then end. Just a suggestion, in case you didn't see it in an earlier post.
I'll start the 18mg dose every 3 days in about 1 week from now. I'll post my results then. So far pretty good, although the end of 2nd day with no meds, I start feeling wierd.
-Jammer
Posted by KatieC on April 8, 2001, at 12:08:22
In reply to Re: New to Effexor XR, my side effects, anyone else?, posted by Cindy W on August 28, 2000, at 21:57:24
Hello to all,
I have read alot of the horror stories on here regarding the withdrawal symptoms... the fact that some of them may be permanent and the other people that refute that fact. I have been on effexor xr for a little over 3 months now. I felt the difference with the very first pill. I thought I had found the greatest thing since sliced bread. I had been experiencing mild to moderate depression truthfully for years...but was now really feeling the effects of it. My med doctor put me on Effexor xr because I told her I wanted something with a low risk of weight gain (I'm only 21 and have struggled with my weight for years, Had lost about 35 pounds 2 years ago and HAD kept it off) and something with low sexual side effects since I am a newlywed.
The first two weeks or so I had the constant yawning, the sleepiness, and the constant headaches. My body adjusted however and I loved the drug.
I now, however, want to talk to the doc about getting off of it. I have gained about 25 pounds in the last 2 1/2 months. HUGE appetite increase. I am tired again. And, the dreams are amazing. I can honestly say I have had screwy dreams all my life...but now they are REALLY weird. I have also recently started experiencing night sweats. I never had them before...but now I wake up my legs and arms are all sweaty. I'm wearing shorts and that doesn't seem to make a diff.
I'm really scared however after reading all the horror stories about the withdrawal. Can anyone give me any ideas as to what to do?
Can anyone suggest any other Antidepressants (preferably non MAOIs) that may not be so bad with weight gain...but still low sexual side effects?
Any info would be appreciated. Thanks. I wish you all the very best of luck.
Posted by jerz on April 8, 2001, at 18:32:11
In reply to Re: Effexor withdrawal FYI, posted by michellec on April 8, 2001, at 9:10:44
> > I have been on Effexor XR for just over one year, @ 300 mg/day. I decided to stop taking it and went cold turkey. Big mistake, I had severe withdrawal symptoms. So, I went back on it am on now going off slowly. I open the capsules, weigh out the dose, and then refill the capsule with the amount I’m after. I’m a chemist so this is easy for me. I thought the following information might help those of you also trying to go off this stuff.
> >
> > Each 150 mg capsule of Effexor XR contains 500 mg of white beads (so, the beads are 30 % by weight Effexor). 25 beads contain 11 (+/-2) mg of Effexor. All you need to do is open the capsules, pour out the beads, count out how many you need, and then put the lowered dose back in the capsule. Do not swallow the beads directly, be sure to put them back in the capsule. I do a bunch of pills at once, first emptying several capsules into a vial or envelope, then measuring what I want back into the empty capsules. You will notice that the Effexor beads are fairly uniform in size, but there will be some smaller ones as well as some that are fused together. Try to count out the beads randomly, don’t go for just the large one or just the small.
> >
> > Hope this helps, seems to be going ok with me. I am experiencing uncomfortable withdrawal symptoms but they are nothing compared to the first time and I can easily control the symptoms with the dosage size and length time I am at that dose before decreasing further.
> >
> > Good luck
> >
> > Ishmael
Hope you can answer a quick question... My daughter and I are both trying to wean off 37.5 and are having difficulty. We'd like to try the 18.75 mg, etc. but all I have left are 75 mg capsules. Is it simply a matter of dividing the white balls into fourths and then taking that dose in a capsule? Sorry if this is a stupid question but, like many others, I've lost several brain cells during my stint on Effexor XR! Thanks. Jerz
Posted by Robin on April 8, 2001, at 21:46:37
In reply to Re: withdrawl going well, posted by JAMMER on April 7, 2001, at 9:12:10
Thanks for the advice Jammer. Sounds like a plan I'll definitely have to try. Hope everything goes well for you. Keep me posted!
Robin :)
Posted by SCALLOPSHELL on April 11, 2001, at 11:16:11
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
I'm new on Effexor XR-37.5mg for 2 days and today I am feeling very tense, nauseated and "spacey".Is this normal and how long does it last? I'm thinking about stopping the medication because I don't like how it is making me feel. I'm very petite and can't afford to have nausea and no appetite.Any feedback from anybody?
Posted by mstar on April 11, 2001, at 11:49:03
In reply to Re:side effects, posted by SCALLOPSHELL on April 11, 2001, at 11:16:11
I have been taking Effexor XR for about a week. I have had a very up and down week. I feel better during the day and noticed an increase in energy, but I start to fade at 7:30 with nausa, I yawn all the time, have dizzy spells and can barely walk I am so tired and weak. But I never sleep though the night. Has this happened to anyone else? I am on 3 days of 75mg, I take it in the morning.
Posted by AnneL on April 11, 2001, at 12:08:16
In reply to New user!, posted by mstar on April 11, 2001, at 11:49:03
> I have been taking Effexor XR for about a week. I have had a very up and down week. I feel better during the day and noticed an increase in energy, but I start to fade at 7:30 with nausa, I yawn all the time, have dizzy spells and can barely walk I am so tired and weak. But I never sleep though the night. Has this happened to anyone else? I am on 3 days of 75mg, I take it in the morning.
Hi, Anne speaking,
Did you start at 37.5 mg. daily for the first week? The low dose taken for 4 to 7 days help the body to adjust and minimize nausea. Insomnia is a very commom complaint, your pdoc can help suggest either other the counter (OTC) medications that help with sleep such as Benadryl brand name for diphenhydramine, Tylenol PM (which is just Tylenol (Tylenol with Benadryl) or a non-benzodiazapine sleep medication such as Ambien or Sonata. I am currently taking Effexor XR 75 mg. daily and also take Klonopin 1 mg. at night for sleep. I did feel spacy, tired at all the wrong times and insomnia just like you. Nausea has not been a problem for me, make sure you take it with meals and do continue to take your dose in the morning as well. I made the mistake of taking it at around 5PM and I was up all night! The nausea is a common side-effect of Effexor, but it will pass! Ask your doctor for something that may help calm your stomach, maybe Zantac will help. Hang in there! All of your side-effects will dissipate given just a little bit more time! Good Luck and keep us posted.
Posted by DavidHIFI on April 11, 2001, at 22:06:48
In reply to Re:side effects, posted by SCALLOPSHELL on April 11, 2001, at 11:16:11
> I'm new on Effexor XR-37.5mg for 2 days and today I am feeling very tense, nauseated and "spacey".Is this normal and how long does it last? I'm thinking about stopping the medication because I don't like how it is making me feel. I'm very petite and can't afford to have nausea and no appetite.Any feedback from anybody?
I'm also new at this and I found that the weirdness and nausia go away. For me it took three weeks. Many previous posts mentioned the time it takes for this stuff to work, as much as six weeks, so tough it out if you can. I had the starter kit that started at 37.5 for a week than on to 75 for the long term. I decided to stick with 37.5 for a while. I've chosen to take it slow, but if you want to stop, I'd suggest reading previous posts about weaning off this stuff. Don't go cold turkey, it can get nasty.
Posted by DavidHIFI on April 11, 2001, at 22:10:09
In reply to New user!, posted by mstar on April 11, 2001, at 11:49:03
> I have been taking Effexor XR for about a week. I have had a very up and down week. I feel better during the day and noticed an increase in energy, but I start to fade at 7:30 with nausa, I yawn all the time, have dizzy spells and can barely walk I am so tired and weak. But I never sleep though the night. Has this happened to anyone else? I am on 3 days of 75mg, I take it in the morning.
Talk to your doctor about getting 37.5 for a week before stepping up to 75. Seems wrong to start at 75.
Posted by SCALLOPSHELL on April 13, 2001, at 7:42:19
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
I AM GOING OFF THIS AWFUL MEDICATION. IT HAS MADE ME EXTERMELY NAUSEOUS AND I HAVE BEEN VOMITING FOR 2 DAYS. I HAVEN'T WANTED TO GET OUT OF BED AND I FEEL VERY DEPRESSED. HATE IT! I'LL NEVER TAKE THIS AGAIN.
Posted by sabnyc on April 13, 2001, at 14:37:14
In reply to Re: New user! » mstar, posted by AnneL on April 11, 2001, at 12:08:16
I'm on my third day of effexor XR (37.5m), and am having, what I believe are normal, but unpleasant side effects. I'm very spacy, hard to concentrate, jittery and tired at the same time, and sleep is bad (MD gave me Ambien for that). I'm taking the med for a mild non-debilitating, depression (or fear of going into one). I'm turning 50, lost job, broke, scared about the future etc. I didn't want to spiral down, I need all my wits about me to confront these things. (I took zoloft 5yrs. ago for about 9mos. and it really helped). Is there anyone else in a similar situation? I most likely could handle this without the med, but I want to use everything I can...I write and am also concerned about the effect on that. I'd appreciate hearing from you.
Posted by SCALLOPSHELL on April 13, 2001, at 14:52:06
In reply to Re: New user! » AnneL, posted by sabnyc on April 13, 2001, at 14:37:14
I felt absotulely awful on Effexor and by the third day I had to give it up. I had all the symptoms you had plus severe nausea and vomiting.I was taking this for menopausal symptoms and I would rather have those than the side effects from Effexor anyday! Good luck.
Posted by AnneL on April 13, 2001, at 14:59:56
In reply to Re: New user! » AnneL, posted by sabnyc on April 13, 2001, at 14:37:14
> I'm on my third day of effexor XR (37.5m), and am having, what I believe are normal, but unpleasant side effects. I'm very spacy, hard to concentrate, jittery and tired at the same time, and sleep is bad (MD gave me Ambien for that). I'm taking the med for a mild non-debilitating, depression (or fear of going into one). I'm turning 50, lost job, broke, scared about the future etc. I didn't want to spiral down, I need all my wits about me to confront these things. (I took zoloft 5yrs. ago for about 9mos. and it really helped). Is there anyone else in a similar situation? I most likely could handle this without the med, but I want to use everything I can...I write and am also concerned about the effect on that. I'd appreciate hearing from you.
Your start-up side effects sound very much like mine did. I even stopped taking it after only 3 days, but my depression which was compounded by situational stressors was so bad that I became very motivated to stick it out! I'am really glad that I did. I started at 37.5 mg. x 7 days, went to 75 mg. x 15 days and am now on 112.5 mg. I had absolutely no problem upping the dose to 75 mg. (well maybe jittery for a day or two) but then it was gone! I am now experiencing the same "ramping up" feeling on day 2 at 112.5 mg. but am confident this will pass in a day or two. Only you can decide whether or not you require medication at this time in your life. Perhaps asking for medication from your doctor is an indication that you feel the need is great enough.
Good Luck and keep us posted. AnneL
Posted by JAMMER on April 13, 2001, at 15:00:57
In reply to Hate it! , posted by SCALLOPSHELL on April 13, 2001, at 7:42:19
> I AM GOING OFF THIS AWFUL MEDICATION. IT HAS MADE ME EXTERMELY NAUSEOUS AND I HAVE BEEN VOMITING FOR 2 DAYS. I HAVEN'T WANTED TO GET OUT OF BED AND I FEEL VERY DEPRESSED. HATE IT! I'LL NEVER TAKE THIS AGAIN.
> It is VERY important to wean of this medication slowly. Tapering slowly to lowest dose over several weeks, then splitting the dose in half for 2 weeks, and half again is what I'm doing, taking it everyday. For XR, 37mg 2 weeks, 18mg 2weeks, then 9mg for weeks is my plan. I'm at the end of 1st week at 18mg.
Yes, getting off this med SUCKS........At the end of 2nd day with no use brain shivers set in with other negative withdrawal symptoms. (see my previous posts).
My experience has taught me to get back on it. and begin tapering by reducing the dose. and all the ugly withdrawals, will subside. Mild headaches and some anxiety are my only symptoms.
Best wishes
Jammer
Posted by Denny on April 13, 2001, at 15:38:04
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
> I"M back on 75 Mg. of Effexor and I feel great! The so called terrible withdrawl symptoms were nonexistant because I tappered off Slowly;however the anxiety I experienced felt awful-no other anti-depressent has ever helped me like Effexor does and the few longterm side-effects are very mild and quite managable! To all the newbies and longtime users of this wonderful med, dont be swayed by the postings of mentally ill people who go off their meds and blame their depressive symptoms on withdrawl or longterm side effects: also BEWARE THE BRAINWASHED SCIENTOLOGISTS who oppose all psychiatric medication based on the lunatic ravings of a dead science-fiction pulpwriter!!
Posted by violalloyd on April 13, 2001, at 16:35:48
In reply to New user!, posted by mstar on April 11, 2001, at 11:49:03
> I have been taking Effexor XR for about a week. I have had a very up and down week. I feel better during the day and noticed an increase in energy, but I start to fade at 7:30 with nausa, I yawn all the time, have dizzy spells and can barely walk I am so tired and weak. But I never sleep though the night. Has this happened to anyone else? I am on 3 days of 75mg, I take it in the morning.
I wish I had found these boards when I was first put on Effexor! I would have talked to my Dr. about alternatives, and would never have gotten up to 112.5 mg/day.
I took it for 2 years, and am going through horrible withdrawl, even though I am gradually decreasing my dosage.
Reading posts by others going through withdrawl has been a great help to me. The electrical shock sensations and the shakes and jitters are horrible.
Thanks to all who have posted.
Viola
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