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Re: Zyprexa withdrawal - baby steps, and slowly slowly » linkadge

Posted by ronaldo on December 11, 2006, at 1:52:03

In reply to Re: Zyprexa withdrawal - baby steps, and slowly slowly, posted by linkadge on December 10, 2006, at 15:55:55

> I think this is probably a warning that was applied to other antihistamines with effects on monoamine uptake, but would not occur with cyproheptadine.
>
> I agree that certain antihisamines like benydryl or chlorpeniramine with measurable effect on serotonin uptake should not be combined with MAOI's, but I don't think cyproheptadine would pose a problem as it has no effect on monamine uptake.
>
> It is a serotonin antagonist that is often used to treat serotonin syndrome, should it occur.
>
> I am not saying this is the final answer, but I think it was probably a carryover warning from other antihisamines.
>
>
> Linkadge

Hi Linkadge

Cyproheptadine.com - The official site for cyproheptadine... carries the same warning:

"Before taking Cyproheptadine:
Please inform your doctor if you are taking any of the following medicines: anxiety or sleep medicines such as alprazolam (Xanax®), diazepam (Valium®), chlordiazepoxide (Librium®), temazepam (Restoril®), or triazolam (Halcion®); medications for depression such as amitriptyline (Elavil®), doxepin (Sinequan®), nortriptyline (Pamelor®), fluoxetine (Prozac®), sertraline (Zoloft®), or paroxetine (Paxil®); or any other medications that make you feel drowsy, sleepy, or relaxed."
....

"So too, do not take cyproheptadine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan®), phenelzine (Nardil®), or tranylcypromine (Parnate®) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects."

http://www.cyproheptadine.com/cyproheptadine_precautions/

Luckily this warning would not affect me as I don't use any of the above. But many of the above listed medicines are used by babblers.

Better I say to err on the side of caution.

...ronaldo


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poster:ronaldo thread:712455
URL: http://www.dr-bob.org/babble/wdrawl/20061010/msgs/712488.html