Posted by KayeBaby on July 22, 2006, at 13:39:23
In reply to Re: Lyrica (pregabalin) » KayeBaby, posted by SLS on July 22, 2006, at 6:34:16
> Hi KB.
>
> > I have Non Verbal Learning disorder which looks and acts much like mixed ADD and possibly Biporla II (Hypomanias induced by mosty by meds)
> > My depressions are of the atypical sort. Hypersomnia, weight gain with the ability to temporarily pull out.
>
> That's interesting. It was a pet idea of mine that mood reactivity would not be a feature of bipolar disorder. Oh, well.
>>>>
>>>> The bipolar II is not an official diagnosis (my dr doesn't really believe in putting too much stock in a particular label) The ADD NLD are official or official as it gets. If I had a Doc fond of naming I could see the Bipolar II getting thrown in the mix-so don't let this mess with your theory too much. :)
> > I have taken almost all stims available aside from desoxyn. Right now I am on Didrex and Dexedrine spansules 10mg per day.
>
> I might give sibutramine (Meridia) a try soon. It is a drug currently approved for obesity, but was originally developed as an antidepressant. It seems to be effective for fibromyalgia and Tourrettes. Its metabolites seem to be more potent dopamine reuptake inhibitors than Wellbutrin, Effexor, or Cymbalta. It might be an interesting drug for you to investigate.> >>>>I have tried all of these with some positive effects but in the end they all end up turning on me. Cymbalta was alternately stimulating and sedating with a good stretch being stimulating. Wellbutrin is reliable for pulling me out of a depression but I dare not go above 200 mg or it will make me horribly depressed-it is interesting that cymbalta, wellbutrin, strattera, and ritalin all have some positive effects in lower than usual amounts but flattening (I mean flat like almost catatonia)
It is a ridiculous balancing act that I cannot maintain. The longer I use these agents the more sensitive I become to the flattening effect until I canoot tolerate any amount. This happened with strattera as well. Also dexedrine-less is more I guess.
The regular switching of my meds gives me a constant feeling of insecurity. Every day is a new day and what worked yesterday may not work today. I always fear when I am starting something new going on vacation etc. I have had my meds fail me and ruin many a vacation.My self-obsevational skills are poor and I am always surprised by changes in response to my meds. Whine,whine, whine.......ya know
> > I also have an element of post viral fatigue/cfs which clouds the issue somewhat due to some purely biological exhaustion.
>
> Ah. Interesting. Given the association between CFS and fibromyalgia, sibutramine becomes a more attractive drug for you.
>
>>>>I have kept this drug in mind but have not jumped due to my past history with similar agents.
My p-doc says to try EMSAM next and if I want Parnate. I have no exp. with this class of drugs. I am afraid to start Emasam because i am starting school (career change) this fall and I don't want to be screwed up when I do. I have not been entirely off stims in the last 5 years and done well at all.
> Thanks for giving me your impressions of Lyrica. I'll definitely keep it on my list of things to try. I wish it didn't have such a short half-life, though.
>
>>>Yes there is an up-down effect.
And you are very welcome I have learned alot from your posts and am happy to be of any help to you.
> I have had weird reactions to mood-stabilizers. They will sometimes give me a brief mild mood lift in the beginning and then leave me feeling flat. Lithium, Neurontin, and Depakote did that. I have been taking Lamictal for a few years. It seems to help a bit when combined with an antidepressant. Right now, Topamax is giving me a slight improvement in mental energy and focus, although it might be fading. It is hard to tell. I am currently taking 125mg. I am thinking that I should work up to 200mg before giving up on it.
>
> Thanks again for your reply. It was very helpful.
>
>
> - Scott
>
>>>I have not taken any of these but lamictal for just a few days. WOW! at 12.5 mg for 3-4 days I was just flying! Now i know exactly what hypomania is. It was classic. Why would I have that response to an anti convulsant/mood stabalizing agent-does anyone know???\
I will be watching your progress with interest, Scott.
Do you ever feel like we are our own pet project?
Thanks Much!
Kaye
poster:KayeBaby
thread:668258
URL: http://www.dr-bob.org/babble/wdrawl/20060627/msgs/669373.html