Posted by JahL on July 12, 2005, at 18:28:42
In reply to Opioids as a treatment of last resort - Metyrapone » JahL, posted by SLS on July 10, 2005, at 22:32:47
Hi Scott.
>
> One day at a time, right?
>
> It really sucks.
>
> I know.
>
> I wish things were different.You *know* the script. Different? Maybe one day. Here's hoping for us both.
> How would you go about getting mifepristone? Would you need to enter a study?
Yes, joining a study appears to be the only way of obtaining it legally for affective disorders and quite how one qualifies for these studies, is beyond me. Over the years I have asked numerous pdocs and professors if they could enter me into a given study, but to no avail. The study in Newcastle requires that participants take only Lithium and Valproate - impossible for me.
Otherwise, only abortion clinics may administer it, one course at a time.
However...we've found an online pharmacy - just the one - that purports to sell it. Unfortunately it's very expensive (600mg daily works out at about $1,000+ a week!) and they're currently 'sold out'. (If you want the name of the pharmacy I'll email it to you)
We're now looking to import direct from India - where prices are far more reasonable. The main stumbling block (aside from the illegality of it all, although my life comes before petty laws) is that it's only available in bulk to businesses, making the next step to form a company to accept the meds (the things we have to do to acquire some quality if life...). I'll keep you posted on what happens.
> One thing you might want to look into is metyrapone.
Thanks. That rings a bell. I'll email my pdoc now to see if he will give it some consideration.
> If it doesn't work, perhaps it will give you enough of a partial or transient improvement to warrant further exploration of HPA stuff and further pursue mifepristone.
I was kind of thinking along those lines also. If nothing else, any kind of a response would provide me with considerable ammunition in my quest to get Mifepristone legally prescribed.
It seems that Mifepristone is the most exciting thing out there for two die-hard med-heads like you and I, who have seen it, done it. Can I assume that you too are actively seeking it out (and presumably coming up against the same barriers)?
Even my pdoc, instinctively more of a psychologist, had read an article suggesting that cognitive dysfunction is a predictor of a positive response. I know you, like me, have serious issues with cognition...
Even if it didn't do much for the depression, just imagine being able to think clearly again...
Jamie.
poster:JahL
thread:500631
URL: http://www.dr-bob.org/babble/wdrawl/20050712/msgs/526847.html