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Re: Sometimes there's no choice

Posted by SLS on March 9, 2005, at 7:48:06

In reply to Re: Sometimes there's no choice » SLS, posted by Sarah T. on March 8, 2005, at 23:54:32

Hi Sarah.

> > > > > but one of my doctors told me that most patients who experience daytime sleep attacks on one MAOI will experience them on the others as well.
> >
> > I don't think that is accurate. It seems to be pretty specific to Parnate. >
> > > > > > > - Scott
>
> It occurs with Parnate and Nardil. This has been documented in various journal articles over the years. Most of the references I'm aware of were published before selegiline was used, and I haven't checked to see whether there is anything in the literature about selegiline causing the same problem. One reference I'm aware of regarding Nardil and Parnate is the following:
>
> Teicher MH, Cohen BM, Baldessarini RJ, Cole JO. "Severe Daytime Somnolence in patients treated with an MAOI." AMERICAN JOURNAL OF PSYCHIATRY. 1988 Dec; 145(12): 1552-6.
>
> When I had this problem, one of my doctors called Dr. Teicher at McClean Hospital. I spoke with Dr. Teicher, also, and I must say that he was very helpful and very kind to me.

My experience is anecdotal, of course, but I found that the initial daytime sedation associated with Nardil disappeared and was replaced by a pleasant stimulation. I hope this can be generalized to the majority of people. The paper you cited described 8 people out of the 100s that McClean had treated. In addition, they didn't enumerate how many of the 8 had been on Nardil. I still think the profound daytime sleepiness is more common with Parnate and perhaps even specific to that drug based on the number of people reporting it on PB.

Have you tried Nardil and Parnate? I found them to be very different drugs in many respects.


- Scott

 

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