Posted by Patient on March 2, 2005, at 15:30:01
In reply to Re: Immensely relieved! » Patient, posted by SLS on February 27, 2005, at 13:31:14
> Hi.
>
> > Cymbalta is a heavy duty wide-effecting AD that I'd only use it as a last resort AD-Effexor is also in this class. I'd never use it as a first choice med.
>
> Is it the potential to experience withdrawal effects upon discontinuation of these drugs the only reason why you feel this way?
>
>
> - ScottHello,
No, for they all can cause withdrawal effects. From reading other's experiences with Effexor, this particular medicine seems to be a very difficult drug to discontinue-it just seems to get more complaints.
My feelings and thoughts tell me it is safer to start a patient on an SSRI that mainly targets SR inhibition, then an AD that has a high affinity for NE reuptake as well, or even dopamine DA, besides Ser. The "let's hit one neurotransmitter instead of the whole kit and kaboodle neurotrasmitors" approach seems sensical. For me, multi-selective ADs are like taking more than one type of drug-better to start out simpler and see how the patient does on it before tinkering with the other neurotransmitters. I also think NE reuptake drugs in general, cause more severe side effects. It's not just severe withdrawal-Paxil can be placed right up there with Effexor in that contest, with the others coming in behind.
Thanks for asking.
poster:Patient
thread:457481
URL: http://www.dr-bob.org/babble/wdrawl/20050228/msgs/465534.html