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Treatment resistant depression

Posted by Gray on February 11, 2002, at 0:33:09

Hi,
I have really enjoyed reading the posts at this site. I have found the information invaluable. The
people that post here are well-read and have done their
homework when it comes to pharmacology. This is the
most sophisticated chat room concerning psycology and
drug discourse that I have found on the net.The
discussions about foriegn drugs have been informative.
I have struggled with treatment resistant depression
for many years. It was't until I started reading posts
here that I finally figured out that I had a problem
with low levels of dopamine. When I read about Amineptine here and its effect on dopamine a lightbulb
lit up. What I don't understand is why there is so
little talk of dopamine in most of the antidepressent
literature. I recently changed from Reboxetine to
Effexor XR and then added Zyprexa to the Effexor with
very good results. I learned about Zyprexa at this site. JohnL's knowledge has been especially astute.
AndrewB's 'amisulpride answers' is excellent. SalArmy4Me has provided lots of great input. For the
first time in years I'm beating this ugly beast.
I have found that Dexedrine has been an excellent
jumpstarter for my antidepressents and accelerates
theraputic effect. Dex speeds up body metabolism(heart
rate, circulation, brain funtion, acuity, eliminations,
ect.). If one suffers from lethargy as I often have,
the Dex gets some of these bodily systems back on line.
I am interested in discussing dopamine functions
further. They seem to be very complex. As I understand
it there are basically five dopamine pathways that we
know about, two of which are in the limbic area of the
brain. Also does anyone know the meaning of the following terms(abbreviations): Ki(nM)
5HT
Ki NE/ Ki 5HT
Thank you for your input. GRAY


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poster:Gray thread:18062
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