Posted by Conundrum on November 9, 2010, at 21:52:13
In reply to Re: nortriptyline low dose and tachychardia, posted by maggiemae on November 9, 2010, at 21:36:16
Maybe nortriptyline is not the drug for you. You know I just read an interesting article about high norepinpehrine possibly being linked to a loss of joy. It also talks about beta and adrenergic receptors. Here is the link.
http://www.uplink.com.au/lawlibrary/Documents/Docs/Doc25.html
Go to the section titled "norepinephrine studies," The 2nd paragraph in this section talks about anhedonia(loss of pleasure) and how high norepinphrine can cause it.
Good luck at the appointment!
> > When you say you are taking the two together, do you mean nort + a beta blocker or nort and at another time amitriptyline?
> >
> > Can you take nort at night?
> >
> I can not take the nort at night - it is paradoxically stimulating for me. so, i am taking it with extended release propranolol la in the morning.
>
> i have been reading about the genetic differences that cause people to metabolize drugs (like tcas and others) differently. not sure it if is why i cannot tolerate more than 10mg of nortriptryline or why i have the stimulating effect from it, but it is pretty interesting.
>
> recently i have developed some sort of weird insomnia and anxious depression - i can't enjoy things anymore - my joy is gone. it is worse in the mornings and i get a bit of relief sometimes in the evenings.
>
> i wake up repeatedly at night and then at 4 am i am awake in a weird limbo agitated state of unspecified anxiety/depression. i am too tired and unmotivated to get up (what would i do anyway? I can't read or watch tv when i feel like this). i don't really even feel sad - just empty and incapable of doing anything that requires any concentration or energy.
>
> it has been quite insidious and crazy making. i feel so out of control of it - it feels like i have have lost all the brain chemicals that control joy and motivation.
>
> i go to pdoc again later this week. i really hope he will have a plan that will work for me.
Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual dysfunction. )
Country:USA
Currently taking mirtazapine and tianeptine
poster:Conundrum
thread:967489
URL: http://www.dr-bob.org/babble/neuro/20100607/msgs/969503.html