Posted by cumulative on May 29, 2008, at 5:34:28
In reply to Depersonalisation-derealisation, posted by undopaminergic on May 29, 2008, at 1:47:34
Hmm, interesting. Apparently memantine has a D2 agonism component as well. I wonder if that is simply a consequence of NMDA antagonism in the limbic brain, and whether this effect is clinically relevant and responsible for anti-anhedonic effects.
Hey ... as for KO-antagonism and dynorphin, I think you might enjoy this thread on the great mindandmuscle:
http://www.mindandmuscle.net/forum/index.php?showtopic=28350
poster:cumulative
thread:830752
URL: http://www.dr-bob.org/babble/neuro/20080418/msgs/831851.html