Psycho-Babble Neurotransmitters | advanced medication issues | Framed
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What meds can/can't be combined w/ Remeron?

Posted by clipper40 on January 28, 2008, at 22:02:25 [reposted on January 29, 2008, at 1:32:00 | original URL]

What drugs have people here combined with Remeron?

Rxlist.com states that it's not entirely possible to know what Remeron can be combined with because of the P450 thing:

"Drugs that are Metabolized by and/or Inhibit Cytochrome P450 Enzymes

"Many drugs are metabolized by and/or inhibit various cytochrome P450 enzymes, e.g., 2D6, 1A2, 3A4, etc. In vitro studies have shown that mirtazapine is a substrate for several of these enzymes, including 2D6, 1A2, and 3A4. While in vitro studies have shown that mirtazapine is not a potent inhibitor of any of these enzymes, an indication that mirtazapine is not likely to have a clinically significant inhibitory effect on the metabolism of other drugs that are substrates for these cytochrome P450 enzymes, the concomitant use of REMERON® with most other drugs metabolized by these enzymes has not been formally studied. Consequently, it is not possible to make any definitive statements about the risks of coadministration of REMERON® with such drugs."
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I can't imagine that adding a little bit of Prozac or Zoloft for a few days just to help someone with Effexor withdrawal (who is also taking Remeron) could be much of a problem, can you?


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poster:clipper40 thread:809490
URL: http://www.dr-bob.org/babble/neuro/20080114/msgs/809490.html