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Re: Prozac's least selective job on Nuerons » your#1fan

Posted by bleauberry on January 20, 2008, at 12:02:46

In reply to Prozac's least selective job on Nuerons, posted by your#1fan on January 20, 2008, at 1:04:04

Is your prozac brand or generic? Have you ever tried both for a comparison? Any difference?

The little I know is that prozac is a little dirtier than other ssris, not quite as selective for just serotonin, though its effects on other things are probably too low to be meaningful. Paxil, effexor, and zoloft probably have more meaningful effects on other neuros than prozac. But prozac has something different from the others. It is a mild antagonist of one of the serotonin receptors, which causes an increase of brain norepinephrine and dopamine, unlike the other ssris.

All the drugs have effects far beyond what we usually talk about. They turn the volume up or down on certain genes, enzymes, and all kinds of stuff that is over my head when I read it.

Curious of your take on brand prozac vs generic.


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poster:bleauberry thread:807847
URL: http://www.dr-bob.org/babble/neuro/20080114/msgs/807914.html