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Celiac,gluten,depression,weight loss correlation?

Posted by mtom on May 6, 2019, at 18:36:48

Long, sorry: I've read celiac can be associated with depression and weight loss. In recent years, non-celiac gluten intolerance is much talked about and some also associate this with depression & other psychological disorders.

I've had depression to varying degrees for many years. I also have Lupus, an autoimmune disease which has been correlated to depression. Also diagnosed with osteoporosis in my 40's, which also associated with Celiac and Lupus.

I've tested negative 3 times for Celiac.

About 4 years ago I decided to try Gluten Free for a couple of months anyway. I was feeling only moderate depression at the time, can't say it improved, but my digestive system felt better. And I started losing weight - OK because I was a few pounds overweight. But I went back on gluten and my depression got worse and I kept losing weight, a lot of weight.

Have had lots of tests - Thyroid, Glucose Challenge, lots other Blood Tests, CT Scan, Rheumatology panel - found nothing to account for weight loss and depression (my last Lupus tests actually looked fairly good, although they go up and down over time & don't always correlate to symptoms). But my Rheumatologist doesn't think Lupus is the culprit behind weight loss & depression. My GP can only come up with Depression and she thinks maybe the Lupus is contributing. Depression did start concurrent with Lupus, but was mild to moderate initially and no weight loss for many years, only happened when I did gluten-free, and then my depression worsened after I went back on Gluten (and again weight loss continued). Have tried gluten free since - no change in weight or mood.

I recently spoke to someone who tested negative for Celiac 4 times, then got a Celiac rash - did a gluten challenge (i.e. 6 weeks lots of Gluten) and after that her Celiac test came back positive! Also was confirmed by Biopsy. Don't know if depression was one of her symptoms (we chatted only briefly).

Interested in experiences with either celiac or gluten sensitivity and symptoms including unexplained weight loss and depression.




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