Posted by SLS on May 19, 2011, at 2:43:28
In reply to Re: NAC High Dose But No Effect » Questionmark, posted by mogger on May 19, 2011, at 1:01:17
> Try not to get discouraged about nothing yet. You are doing the right thing by sticking with it. Nac has been the most interesting supplement i have taken as it has been so slow going. I didn't have side effects nor do now. My doc says full benefits aren't achieved for six months. I am sensitive to supplements and pharmaceuticals as well so this stumped me. Don't expect side effects.
I am not terribly sure about this, but taking NAC with its attendant conversion into glutathione acts as an antioxidant to protect mitochondria. Mitochondrial damage and dysfunction are noted in depressive disorders. It probably takes time for the pool of mitochondria to be effectively renewed; the rate of which is determined by their turnover rate. This could easily take months. It is important to reduce psychosocial stress to prevent further damage to the new mitochondria. Psychotherapy might allow for a quicker recovery by reducing psychosocial stress, even before there is any response to biological treatment.
- Scott
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