Posted by bulldog2 on October 2, 2010, at 14:11:31
In reply to Re: One Explnation For The Low Success Rate Of ADs, posted by bleauberry on September 28, 2010, at 17:58:42
> I agree with Life Extension in that there are distinctly different types of depression, and each responds better to different meds.
>
> Some antidepressant studies have found it doesn't matter. Different types of depression all responded to the same med.
>
> But, it is easy to look at the fine details of such studies and see them riddled with flaws and incorrectly interpreted data.
>
> Even if someone couldn't get a brain scan to see what they were dealing with, a simple street version would be to try, one at a time, 5htp, tyrosine, dlpa, gaba, glutamine. Somewhere within those short sample trials the patient would discover what feels better and what doesn't. For example, someone responding quickly to DLPA would probably not be a good candidate for lexapro. DLPA is in the norepinephrine/dopamine/opioid spectrum...barely any effect on serotonin. While 5htp is pure serotonin. More than likely, the patient would find some combination of two or three of those substances in a custom recipe.Very good post. I think we as patients need to read more and guide our p-docs. I believe mine is open minded and will listen to my suggestions.
I always believed that depression was a broad disease category such as cancer is. Sometimes different cancers might use a combo that has a similar chemo agents but usually each cancer has some unique chemo agents that only that tumor type will respond to.
Scientists at these pharm companies keep looking for a silver bullet that will work on all depressions. I don't believe they will find it. They need to define the subcategories of depression and work on them as a separate disease entity.
poster:bulldog2
thread:964112
URL: http://www.dr-bob.org/babble/alter/20100930/msgs/964491.html