Posted by nolvas on October 13, 2009, at 3:14:44
In reply to Re: Pyroluria - Zinc and B6 » tel1kdj, posted by Deneb on October 12, 2009, at 21:15:34
Be careful with high doses of Vitamin B6, follow the advice below, also note that P5P has not been associated with toxicity in large doses as B6 has, so for safety's sake I'd prefer P5P over B6 in large doses and as you probably know it's the active form of B6 anyway, so the body doesn't need to convert B6 to the active form via the liver, and you certainly don't want to burden the liver, it has enough to do with detoxifying the body anyway as well as it's other numerous biological activities >
"Vitamin B6 is usually safe, at intakes up to 200 mg per day in adults. However, vitamin B6 can cause neurological disorders, such as loss of sensation in legs and imbalance, when taken in high doses (200 mg or more per day) over a long period of time. Vitamin B6 toxicity can damage sensory nerves, leading to numbness in the hands and feet as well as difficulty walking. Symptoms of a pyridoxine overdose may include poor coordination, staggering, numbness, decreased sensation to touch, temperature, and vibration,; and tiredness for up to six months."
This is also very informative regarding B6 >http://www.thorne.com/altmedrev/.fulltext/6/1/87.pdf
Please look at the section Safety, Toxicity and Side Effects.
poster:nolvas
thread:920644
URL: http://www.dr-bob.org/babble/alter/20090727/msgs/920762.html