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Supplement 'Arginine' as an AD.... [for QBSBROWN]

Posted by myco on April 4, 2009, at 19:04:10

Hi Brian,

Just looking into another sup here...i'm gonna begin this one shortly...no experience with it yet. Called 'arginine' its a precuror to a brain neuro called 'agmatine'. Agmatine increases monamine levels (NE, DA, adrenalin, but not SE) similar to desipramine (a tca). It works by blocking NMDA receptors (glutamatergic receptors) similar in the way memantine works.

I'm real curious about this one as an augment to nardil. It's easily available in sup stores if you wanna try. Or are you turned off by the tyrosine and dopa bean trials? lol

myco
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References:

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Li et al. Antidepressant-like effect of agmatine and its possible mechanism. Eur J Pharmacol. 2003 May 23;469(1-3):81-8.

Link: http://www.ncbi.nlm.nih.gov/pubmed/12782188?ordinalpos=16&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

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Halaris et al. Agmatine : metabolic pathway and spectrum of activity in brain. CNS Drugs. 2007;21(11):885-900.

Link: http://www.ncbi.nlm.nih.gov/pubmed/17927294?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

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