Posted by Neal on March 16, 2009, at 22:35:51
In reply to Natural Stimulants?, posted by myco on March 16, 2009, at 19:41:05
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This is the board to post this:
Some personal experiences with the endogenous hormone (made in the human body), Dehydroepiandrosterone (DHEA). Dosage 3mg/day Male subject
Originally taken to help with an asthma condition because it is relatively cheap. It seems to brighten the mood slightly. It helps give energy that the asthma has taken away; puts gas in the tank, as it were, to do work, physical or mental. In common with buproprion, it can cause irritability and impatience and make you jumpy. Seems to build "male" morale. If too much is taken per day, it can build-up and cause anti-social actions and arguments. Seems to sharpen thinking and help spot patterns of behavior. Correct dosage is very important, and can only be learned by trial and testing. My dosage was 3-5 mg/day. Websites touting 25, 50 or even 100 mg/day are irresponsible in my opinion. For asthma or resperatory sufferers, it may be worth investigating. Not sure if a healthy subject would benefit.
According to the Mayo Clinic website: "There is some evidence supporting the use of DHEA in the treatment of adrenal insufficiency, depression, induction of labor, and systemic lupus erythematosus."
further info on the Mayo Clinic Site:
http://www.mayoclinic.com/health/dhea/NS_patient-dheaAdditional info from the web:
"Some small placebo-controlled randomized clinical trial studies have found long-term supplementation to improve mood and relieve depression or to decrease insulin resistance. However, a larger placebo-controlled randomized clinical trial reported in the New England Journal of Medicine in 2006 found that DHEA supplementation in elderly men and women had no beneficial effects on body composition, physical performance, insulin sensitivity, or quality of life."
"In contrast to the non-beneficial effects of DHEA on memory in the elderly, a randomised UK study found that a 7-day course of DHEA (150 mg twice daily) improved episodic memory in healthy young men. In this study, DHEA was also shown to improve subjective mood and decrease evening cortisol concentration, which is known to be elevated in depression. The effect of DHEA on memory appeared to be related to an early activation of the anterior cingulate cortex (ACC) and it was suggested this was due to neuronal recruitment of the steroid sensitive ACC that may be involved in pre-hippocampal memory processing."
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poster:Neal
thread:885663
URL: http://www.dr-bob.org/babble/alter/20090204/msgs/885704.html