Posted by desolationrower on February 23, 2009, at 19:51:54
In reply to Natural anticonvulsants?, posted by SLS on February 20, 2009, at 16:50:47
don't have time to do anything but what i can think of but off the top of my head here
(exams the next few days i should get back to) :> What substances:
>
> 1. Act as anticonvulsants?
>
> 2. Act as anti-glutamatergics
>
> 3. Act as NMDA receptor antagonists?
>
> Thanks.
>
> - Scottminerals zinc & magnesium are important to nmda function, deficiency causes problems (but there is an upper limit to the antagonism you can get, they dissociate quicker than something like memantine. you can't take a 10g magnesium version of ketamine dissociative khole trip)
i believe cat's claw has some of the 2&3
huperzine is an nmda antagonist, i forget the type, as well as ACHtr.inhibitor
ibogaine!
taurine, nmda i think, don't cross BBB well
neurosteroids, i think some are proconvulsant, but some are gabaa agonists and allostatic modulators
magnolia bark is probably anticonvulsant, from the GABA side of things (i think all the GABAa subtypes are anticonvulsant?). so, similar gaba drugs like muscimol, kava, etc. theanine probably too. most of these have too short a t1/2 to be useful for this purpose. oh and don't forget about scotch.do you know someone who wants a otc alternative to her lamictal, or you just thinking stuff through?
-d/r
poster:desolationrower
thread:881348
URL: http://www.dr-bob.org/babble/alter/20090204/msgs/882012.html