Posted by azalea on September 28, 2008, at 17:51:06
In reply to Re: DL-Phenylalanine or TMG experiences anyone?, posted by curious1 on September 27, 2008, at 15:01:36
Here's 1 study on DLPA:
Dl-phenylalanine in depressed patients: an open study.
Beckmann H. Strauss MA. Ludolph E.
Journal of Neural Transmission. 41(2-3):123-34, 1977.In an open study dl-phenylalanine in doses from 75-200 mg/day was administered to 20 depressed patients for 20 days. Patients were classified according to the International Classification of Diseases (ICD). The AMP system, the Hamilton depression scale and the von Zerssen self rating questionnaire were used for documentation of psychopathological, neurologic and somatic changes. In addition a global clinical impression was agreed upon by experienced psychiatrists. At the end of the trial 12 patients (8 with complete, 4 with good response) could be discharged without any further treatment. 4 patients with partially untypical depressions experienced mild to moderate responses, whereas 4 patients did not respond at all to the phenylalanine administration. Depressive "core symptoms" as depressed mood, retardation and/or agitation were preferentially, anxiety and sleep disturbances moderately and hypochondriasis and compulsiveness were not influenced. It is concluded that dl-phenylalanine might have substantial antidepressant properties and that further more controlled investigations are warranted.
> Interesting about the study using only 50-75 mgs of DLPA.
>
> I took 500 mg for 3 or 4 days in a row.
>
> First day I was irritable and angry.
> Second day I felt over-stimulated, but less irritable.
> Third day felt pretty darn good, happy, music sounded better. Basically felt great!
> Then on the fourth day I felt horrible, headachy, down, almost migraine headachy.
>
> Maybe I was taking wayyy too mcuh and 50-75mg a day is the way to go??? It did work very well for a day or 2.
>
> Thanks for the information, I will try DLPA again at a much lower dose.
poster:azalea
thread:850588
URL: http://www.dr-bob.org/babble/alter/20080612/msgs/854652.html