Posted by linkadge on April 11, 2007, at 18:41:29
In reply to Re: For how long can I take valerian?, posted by nolvas on April 11, 2007, at 16:49:57
I actually had the same question. I think there have been a few cases of liver problems, but the articles didn't seem to directly link it to valerian, perhaps with other skullcap or germander ingredients.
One may or may not build a tollerance since there are multiple mechanisms for kava. Some involve serotonin receptor agonism and antagonism, opiate modulation, inhibition of gaba metabolism, and gaba receptor agonism.
Valerian has affinity for 5-ht1a which may help to reduce anxiety after longer term administration. Ie in a manner similar to buspar.
Linakdge
poster:linkadge
thread:748896
URL: http://www.dr-bob.org/babble/alter/20070410/msgs/749132.html