Posted by blueberry on November 17, 2006, at 6:53:06
In reply to A new experience - happiness!, posted by aeon on November 16, 2006, at 22:23:30
You offered to post more detailed info if anyone was interested. Yes, you have my interest.
Specifically though I am interested in the various compounds.
Quercetin...what is it.
GLA...what is it.
DHEA...I've tried it before and got stunningly depressed on it, why was that?Say for example someone stuck on prozac longterm, similar to you being stuck on maoi longterm, went out and bought all this stuff and started taking it at perhaps half dose at first to get started...what kind of side effects would you expect?
And how long is the lag time before it starts to really work?
How is your sleep?
How is your sex life? Desire? Ability?
And anything else you would like to share.
You are very kind to share and I am so thankful you have been blessed after all your rocky roads and determination.
> Hi
>
> I'm new to posting here, though I've read the boards for years. Thought I'd start posting, dunno why maybe its because I'm finally feeling better?
>
> I've suffered from depression since age 20 now 32, at times its been bad, real bad. I have a diagnosis of BP II because of a couple of manic episodes which were caused by meds. MOst of the time though I'm just massively dysthymic, anhedonic and I just drag myself through each day.
>
> I have severe bad reactions to SSRI's and both times it was a different SSRI. I am mad keen on natural treatments and have spent tens of thousands of dollars trying to kick this thing with them.
>
> Now I am on Parnate 40mg and I have never felt so good! I am also taking high doses of Quercetin and 3000 mg day, 2000mg Folic Acid, 30mg DHEA, 500mg GLA, 1000 mg EPA, Acetyl l-carntine 1gram (I'd take more but its so damn expensive) and Deprenyl 5mg /week or so.
>
> My theory on depression has evolved over the years and now I think I am getting close.
>
> Central is the role of prostaglandins series 1 and 2. I have observed my depression for years and tried to equate the bodily and mental sensation of it to likely chemicals and processes. I have tried targeting only neurotransmitters but this is a band aid approach in my view and often leads to more trouble than its worth.
>
> Also I have in the past thought it could be hormones but this lead to a dead end and no improvement. Of course I've attempted to fix any "deficiencies" both minral and vitamin, taken all kinds of herbs, tried all kinds of mind tricks and therapies etc etc.
>
> Now though I am focussed on Prostaglandins because they fit the feeling of depression. Prostaglandins do not really migrate around, they just sit in the cells and this matches what my depression feels like, it just sits there, does not move, does not flow with the blood, and definitely does NOT emanate from the brain. It is a whole body sensation.
>
> I take the quercetin to knock out COX2 so therefore stop production of the EVIL series 2 prostaglandins. These are the ones that make you feel real bad. Quercetin is a potent COX2 inhibitor, in fact more powerful in high doses than Vioxx, and also is a bit of a mood stabiliser, and MAOI of uncertain strength.
>
> Then I take GLA and EPA to increase series 1 prostaglandins.
>
> The Parnate is because I am addicted to the feeling of being high on neurotransmitters though it does not really help the depression, just masks it. I don't think I'll ever stop that stuff, unless I can find an equally effective natural MAOI.
>
> I know some of you have tried fish oil, GLA etc but the key is having them both in high quality and inhibiting the COX2 enzyme at the same time.
>
> If you just increase series 1 prostaglandins with GLA and EPA you will not feel great because the series 2 being generated by COX2 overrides them (think of when you have a toothache!@ You can go from fine to miserable in half a day - even non-depressives!).
>
> If anyone's interested I can post more detailed analysis of my theories.
>
> Anyway this is getting pretty long winded... just thought I'd make myself known and it sure feels good to be participating.
>
> aeon
poster:blueberry
thread:704435
URL: http://www.dr-bob.org/babble/alter/20061013/msgs/704480.html